Metabolic diseases and healthy aging: identifying environmental and behavioral risk factors and promoting public health

Frontiers in Public Health, Journal Year: 2023, Volume and Issue: 11

Published: Oct. 13, 2023

Aging is a progressive and irreversible pathophysiological process that manifests as the decline in tissue cellular functions, along with significant increase risk of various aging-related diseases, including metabolic diseases. While advances modern medicine have significantly promoted human health extended lifespan, diseases such obesity type 2 diabetes among older adults pose major challenge to global public societies age. Therefore, understanding complex interaction between factors crucial for promoting well-being healthy aging. This review article explores environmental behavioral associated their impact on The environment, an obesogenic environment exposure toxins, strongly correlated rising prevalence its comorbidities. Behavioral factors, diet, physical activity, smoking, alcohol consumption, sleep patterns, influence throughout Public interventions targeting modifiable can effectively promote healthier lifestyles prevent Collaboration government agencies, healthcare providers community organizations essential implementing these creating supportive environments foster

Language: Английский

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Investigating the longitudinal bi-directional relationship between self-reported restrictive eating behaviours and sleep in UK adolescents within the Millennium Cohort Study

European Child & Adolescent Psychiatry, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 28, 2025

Abstract Objective This study aimed to investigate the longitudinal bi-directional relationship between self-reported restrictive eating behaviours and sleep characteristics within a sample of UK adolescents from Millennium Cohort Study (MCS). Method Using Structural Equation Modelling approach, present investigated prospective associations individual (e.g., timing, onset latency, social jetlag) at age 14 17. Moreover, association (age 14) quality 17) was tested. A mediation analysis conducted explore role depressive symptoms in these relationships. In total, N = 6,041 young people provided self-report data both timepoints (sweep 6 & 7) subsample 2,164 additionally diary on their over two separate 24 h periods. Results Sleep indicators did not significantly predict changes across time. However, engagement predicted poorer self-perceived three years later (β 0.06, SE 0.01, p <.01). Depressive fully mediated this (indirect effect: β 0.05, 0.04, <.001). Discussion The provides evidence for positive subsequent large, general population sample. Findings suggest mood as potential target tertiary prevention when addressing an disorder risk factor adolescents.

Language: Английский

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Hábitos alimentarios durante su jornada laboral en un grupo de feriantes hortofrutícolas en un centro urbano de Chile

Salud Ciencia y Tecnología, Journal Year: 2023, Volume and Issue: 3, P. 527 - 527

Published: Oct. 9, 2023

Introduction: free fairs are environments dedicated to the commercialization of fresh products in a public space, their workers being group people characterized by working long hours and with irregular breaks, thus affecting eating habits. Objective: know habits during day fruit vegetable vendors downtown sector city Chillán. Methods: Descriptive cross-sectional design. A sample 87 stallholders was studied, obtained non-probabilistic method for convenience. background questionnaire quantified consumption frequency survey were applied. R package, version 4.1.2 Results: most participants did not meet recommendations bread-cereals meats (excess consumption) fruits-vegetables dairy (insufficient consumption), according dietary guide Chilean population. Excessive fast food, sugary drinks, juices alcohol also observed. Conclusion: lifestyle presented this can trigger various pathophysiological complications medium term

Language: Английский

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Weight Loss Programs: Why Do They Fail? A Multidimensional Approach for Obesity Management

Current Nutrition Reports, Journal Year: 2024, Volume and Issue: 13(3), P. 478 - 499

Published: June 11, 2024

Language: Английский

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Behavioral and Psychological Factors Affecting Weight Loss Success

Current Obesity Reports, Journal Year: 2023, Volume and Issue: 12(3), P. 223 - 230

Published: June 19, 2023

Language: Английский

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Metabolic and functional factors associated with a change in resting metabolic rate among older adults with type 2 diabetes– results from the CEV-65 randomized trial

Heliyon, Journal Year: 2025, Volume and Issue: 11(2), P. e41593 - e41593

Published: Jan. 1, 2025

This study evaluated the effects of circuit resistance training (CRT), a vegetarian/Mediterranean diet (VegMedD), and empagliflozin on Resting Metabolic Rate (RMR) in older adults with Type 2 Diabetes (T2DM). 67 participants from CEV-65 trial (≥65 years, 61 % female) were randomly assigned to CRT, VegMedD, or for 10 weeks. Assessments included RMR, medical, metabolic, nutritional, anthropometric functional measurements. RMR changes analyzed using paired t-tests, effect sizes, repeated analysis variance. No significant differences found between groups at baseline post-intervention minor increases 16 (CRT) 25 (VegMeD/empagliflozin). Factors correlating sleep hours (r = 0.25), fat percentage -0.27), leg strength 0.29), systolic blood pressure 0.24). Except pressure, all other variables predicted (R 0.22). showed similar elderly T2DM. predicting are hours, percentage, strength, those who increased/did not change their presenting greater improvement aforementioned variables. These findings highlight potential these factors as therapeutic targets improving metabolic health warrant further investigation.

Language: Английский

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Qualidade do sono em idosos com hiperplasia prostática benigna

Cuadernos de Educación y Desarrollo, Journal Year: 2025, Volume and Issue: 17(1), P. e7219 - e7219

Published: Jan. 13, 2025

A Hiperplasia prostática benigna (HPB) é uma doença conhecida por acometer homens a partir dos 40 anos e sua incidência aumenta de acordo com idade, sendo encontrada em cerca 80% aos 80 anos. Sua ocorrência se deve ao crescimento do estroma das células epiteliais da próstata, comprimindo região uretra resultando obstrução parcial ou total fluxo urina. O tratamento desta condição baseado no uso alfa-bloqueadores, inibidores 5-alfa-redutase forma cirúrgica pela ressecção transuretral próstata. Os sintomas incluem incontinência urinária, micção excessiva durante noite (noctúria), urinário baixo, gotejamento após urinar, retenção urinária espasmos bexiga. Estes possuem grande impacto negativo nas atividades vida diária pacientes acometidos, gerando problemas psicológicos como ansiedade depressão impactando processos fisiológicos o sono. qualidade sono um parâmetro suma importância para avaliação indivíduos, pois possuí influência sistema imunológico, metabólico hormonal. relação entre idosos HPB ainda incerta, porém os relatados podem levar interrupção frequência, devido constante necessidade ir banheiro. Estas interrupções são extremamente prejudiciais obter bons níveis ocasionam baixa indivíduos acometidos.

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The association of activity patterns on female reproductive diseases: a prospective cohort study of UK biobank

BMC Public Health, Journal Year: 2025, Volume and Issue: 25(1)

Published: Jan. 24, 2025

Little is known about the role of timing physical activity in female reproductive disorders. These disorders include polycystic ovary syndrome (PCOS), heavy menstrual bleeding (HMB), endometriosis, infertility, and pregnancy-related This study aims to investigate associations patterns with diseases. A total 49,540 participants from UK Biobank valid accelerometer data were enrolled at baseline. Activity defined based on moderate-to-vigorous intensity (MVPA) throughout day. Participants categorized into four groups according their MVPA: "morning, evening, mixed, midday-afternoon", midday-afternoon group serving as reference. Cox proportional hazards models utilized evaluate association between During a median follow-up 12.6 years, 1044 cases diseases documented. After adjustment for potential confounders, compared women exercise, morning exercise mixed-timing associated lower risks (HRmorning=0.81, 95% CI: 0.67-0.98; HRmixed=0.79, 0.69-0.91, P-trend < 0.05). Moreover, had PCOS (HRmorning=0.38, 0.15-0.97; HRmixed=0.27, 0.13-0.57, P-trend<0.001), was risk HMB (HRmixed=0.81, 0.70-0.95, 0.05), reference group. Compared group, mixed MVPA groups, but not evening decreased PCOS. In addition, we found that HMB,

Language: Английский

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Lifestyle-Related Factors for Improving Diet Quality

Nutrients, Journal Year: 2025, Volume and Issue: 17(3), P. 448 - 448

Published: Jan. 26, 2025

Background/Objectives: Diet quality is important for the prevention of non-communicable diseases (NCDs), which are now responsible leading causes death worldwide. Although health professionals often recommend diet improvement treatment and management many NCDs, patients continually struggle to make dietary changes maintain them long-term. This may be due an interplay factors that affect quality. paper discusses some lifestyle-related offer additional points intervention use increase Methods: review examines effects exercise, sleep, mindfulness practice, meal socialization, social media use, tobacco alcohol on Studies examining these were found by searching PubMed, CINAHL, Google Scholar. Results: Evidence suggests a positive relationship between adequate all forms have Meal socialization’s nuanced. Individuals tend eat similarly those they share with. However, food quantity intake affected physical characteristics individuals with whom people meal. Social was negative in who used it excessively promote disordered eating patterns. Both impacts Conclusions: Using findings, able educate about can improve

Language: Английский

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The Interplay of Genetic Predisposition, Circadian Misalignment, and Metabolic Regulation in Obesity

Current Obesity Reports, Journal Year: 2025, Volume and Issue: 14(1)

Published: March 1, 2025

Abstract Purpose of Review This review explores the complex interplay between genetic predispositions to obesity, circadian rhythms, metabolic regulation, and sleep. It highlights how factors underlying obesity exacerbate dysfunction through misalignment examines promising interventions mitigate these effects. Recent Findings Genome-wide association Studies (GWAS) have identified numerous Single Nucleotide Polymorphisms (SNPs) associated with traits, attributing 40–75% heritability body mass index (BMI). These findings illuminate critical links clocks, processes. SNPs in clock-related genes influence pathways, disruptions rhythms—driven by poor sleep hygiene or erratic eating patterns—amplifying dysfunction. Circadian synchronized 24-h light–dark cycle, regulate key activities, including glucose metabolism, lipid storage, energy utilization. Genetic mutations external disruptions, such as irregular habits, can destabilize promoting weight gain disorders. Summary individuals disrupts release hormones, leptin insulin, impairing hunger regulation fat storage. Interventions like time-restricted feeding (TRF) structured physical activity offer strategies restore harmony, improve health, obesity-related risks.

Language: Английский

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