Global publication trends and research hotspots of the gut-liver axis in NAFLD: A bibliometric analysis

Frontiers in Endocrinology, Journal Year: 2023, Volume and Issue: 14

Published: March 9, 2023

Background Nonalcoholic Fatty Liver Disease(NAFLD)refers to a spectrum of diseases ranging from simple liver steatosis nonalcoholic steatohepatitis (NASH) and cirrhosis. Bidirectional cross-talk between the gut-liver axis plays an important role in pathogenesis NAFLD. To learn more about NAFLD, this study aims provide comprehensive analysis bibliometric perspective. Method Literature related NAFLD 1989 2022 was extracted Web Science Core Collection. Based on Microsoft Excel, CiteSpace Vosviewer, we conducted analyze number publications, countries/regions, institutions, authors, journals, references, keywords. Results A total 1,891 literature since 2004 included, with rapid growth papers annually. These publications were mainly 66 countries 442 institutions. Of 638 authors analyzed, Bernd Schnabl one most Patrice D. Cani co-citations. International Journal Molecular Sciences is journal articles published, Hepatology citations. The common keywords are gut microbiota, inflammation, insulin instance, which current research hotspots. Short-chain fatty acid, vitro , randomized controlled trial clinical, diabetes mellitus represent frontiers field stage development. Conclusion This first conduct reveals that resistance, short-chain acids, will be hotspots new trends research, could researchers key information helpful for further exploration directions.

Language: Английский

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An Intelligent Approach for Early and Accurate Predication of Cardiac Disease Using Hybrid Artificial Intelligence Techniques

Bioengineering, Journal Year: 2024, Volume and Issue: 11(12), P. 1290 - 1290

Published: Dec. 19, 2024

This study proposes a new hybrid machine learning (ML) model for the early and accurate diagnosis of heart disease. The proposed is combination two powerful ensemble ML models, namely ExtraTreeClassifier (ETC) XGBoost (XGB), resulting in named ETCXGB. At first, all features utilized disease dataset were given as input to ETC model, which processed it by extracting predicted probabilities produced an output. output was then added original feature space producing enriched matrix, used XGB model. matrix training produces final result that whether person has cardiac or not, high accuracy In addition three other DL such convolutional neural network + recurrent (CNN-RNN), long short-term memory (CNN-LSTM), bidirectional (CNN-BLSTM), also investigated. ETCXGB improved prediction 3.91%, while CNN-RNN, CNN-LSTM, CNN-BLSTM enhanced 1.95%, 2.44%, 2.45%, respectively, simulation outcomes illustrate outperformed classical models terms performance measures. Therefore, using will help medical practitioner make healthcare society decrease mortality rate caused

Language: Английский

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Protective effects of paeoniflorin on cardiovascular diseases: A pharmacological and mechanistic overview

Frontiers in Pharmacology, Journal Year: 2023, Volume and Issue: 14

Published: May 30, 2023

Background and ethnopharmacological relevance: The morbidity mortality of cardiovascular diseases (CVDs) are among the highest all diseases, necessitating search for effective drugs improvement prognosis CVD patients. Paeoniflorin (5beta-[(Benzoyloxy)methyl] tetrahydro-5-hydroxy-2-methyl-2,5-methano-1H-3,4-dioxacyclobuta [cd] pentalen-1alpha (2H)-yl-beta-D-glucopyranoside, C23H28O11) is mostly derived from plants family Paeoniaceae (a single genus family) known to possess multiple pharmacological properties in treatment CVDs, making it a promising agent protection system. Aim study: This review evaluates effects potential mechanisms paeoniflorin with aim advancing its further development application. Methods: Various relevant literatures were searched PubMed, ScienceDirect, Google Scholar Web Science. All eligible studies analyzed summarized this review. Results: natural drug great development, which can protect system by regulating glucose lipid metabolism, exerting anti-inflammatory, anti-oxidative stress, anti-arteriosclerotic activities, improving cardiac function, inhibiting remodeling. However, was found have low bioavailability, toxicology safety must be studied analyzed, clinical related carried out. Conclusion: Before used as an therapeutic in-depth experimental research, trials, structural modifications or new preparations required.

Language: Английский

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Traditional Chinese Exercises for Cardiovascular Diseases: A Bibliometric Analysis

Perceptual and Motor Skills, Journal Year: 2024, Volume and Issue: 131(2), P. 514 - 536

Published: Feb. 13, 2024

Traditional Chinese exercises (TCEs) have great value in the prevention and effective treatment of cardiovascular diseases (CVD). Our purpose this study was to summarize present research trends future directions regarding link between TCEs CVD by bibliometrics analysis. We searched Web Science Core Collection (WoSCC) for all original articles reviews on published English before August 7, 2022 using CiteSpace 5.8.R3 Microsoft Excel 2019 software, we displayed results form network maps, line graphs, tables. initially obtained 725 articles. showed that United States most influential country research, with Harvard University prolific institution field, and, Evidence-Based Complementary Alternative Medicine productive journal these The highest-frequency keywords area were Tai Chi, exercise, blood pressure, quality life, older adult. Additionally, important topics included heart rate variability, meta-analysis, Baduanjin breathing exercise. In addition, our revealed among TCEs, Baduanjin, Qigong emerged as extensively studied. However, it’s note exclusive focus literature may led missing results. Future investigators should broaden their search include other databases languages a still more comprehensive overview field.

Language: Английский

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Research progress of circadian rhythm in cardiovascular disease: A bibliometric study from 2002 to 2022

Heliyon, Journal Year: 2024, Volume and Issue: 10(7), P. e28738 - e28738

Published: March 23, 2024

BackgroundGiven that the circadian rhythm is intricately linked to cardiovascular physiological functions, objective of this investigation was employ bibliometric visualization analysis in order scrutinize trends, hotspots, and prospects disease (CVD) over past two decades.MethodsA thorough exploration literature related CVD conducted via Web Science Core Collection database spanning years 2002–2022. Advanced software tools, including citespace VOSviewer, were employed carry out a comprehensive co-occurrence collaborative relationships among countries, institutions, journals, references, keywords found literature. Furthermore, correlation mapping executed provide visual representation data.ResultsThe present study encompassed total 3399 published works, comprising 2691 articles 708 reviews. The publications under scrutiny primarily derived from countries such as United States, Japan, China. most prominent research institutions be University Vigo, Minnesota, Harvard University. Notably, journal Chronobiology International, alongside its co-cited publications, had substantial contribution field. Following an exhaustive analysis, frequently observed identified rhythm, blood pressure, hypertension, heart rate, rate variability, melatonin. nascent indicated future might gravitate towards topics inflammation, metabolism, oxidative stress, autophagy, thereby indicating new directions for investigation.ConclusionThis represents first instance pertaining with through use software. has succeeded highlighting recent frontiers trajectories field, providing valuable

Language: Английский

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A Bibliometric Analysis of the Spatial Transcriptomics Literature from 2006 to 2023

Cellular and Molecular Neurobiology, Journal Year: 2024, Volume and Issue: 44(1)

Published: June 10, 2024

Abstract In recent years, spatial transcriptomics (ST) research has become a popular field of study and shown great potential in medicine. However, there are few bibliometric analyses this field. Thus, study, we aimed to find analyze the frontiers trends medical based on available literature. A computerized search was applied WoSCC (Web Science Core Collection) Database for literature published from 2006 2023. Complete records all cited references were extracted screened. The analysis visualization performed using CiteSpace, VOSviewer, Bibliometrix R Package software, Scimago Graphica. total 1467 papers reviews included. revealed that ST publication citation results have rapid upward trend over last 3 years. Nature Communications most productive co-cited journals, respectively. comprehensive global collaborative network, United States is country with organizations publications, followed closely by China Kingdom. author Joakim Lundeberg paper, while Patrik L. Ståhl ranked first among authors. hot topics tissue recognition, cancer, heterogeneity, immunotherapy, differentiation, models. technologies greatly contributed in-depth fields such as oncology neuroscience, opening up new possibilities diagnosis treatment diseases. Moreover, artificial intelligence big data drive additional development fields. Graphical Spatial application prospects. (1) Imaging-based approaches, including situ sequencing (ISS)—where transcripts amplified sequenced tissue—and ISH-based approaches—where imaging probes sequentially hybridized tissue. (2) NGS-based techniques, which positional information encoded onto prior NGS sequencing.

Language: Английский

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A Bibliometric Analysis of Cardioembolic Stroke From 2012 to 2022

Current Problems in Cardiology, Journal Year: 2022, Volume and Issue: 48(3), P. 101537 - 101537

Published: Dec. 16, 2022

Language: Английский

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Global trends in research related to functional dyspepsia and anxiety or depression over the past two decades: a bibliometric analysis

Frontiers in Neuroscience, Journal Year: 2023, Volume and Issue: 17

Published: Nov. 2, 2023

Functional dyspepsia (FD) is a prevalent global disorder of the upper digestive tract characterized by functional impairment. It often coexists with anxiety/depression, significantly impairing occupational productivity and overall quality life. This study aimed to identify emerging patterns prominent themes within FD anxiety/depression research through bibliometric analysis help explore new innovative avenues for investigating this type FD. A comprehensive review literature encompassing was conducted using Science Citation Index Extension Web Core Collection from 2003 2023. Information extracted comprised "Full Record Cited References." Bibliometric relevant publications, including country, institution, author, journal, citations, keywords, CiteSpace, VOSviewer, Bibliometrix package in R Excel. Studies related have demonstrated an ascending trajectory since 2003. Our identified 338 studies published NEUROGASTROENTEROLOGY AND MOTILITY emerged as most prolific while GASTROENTEROLOGY retained pre-eminence top 10 journals. China two institutions terms volume publications. The Mayo Clinic stood foremost institution publication volume, Chengdu University Traditional Chinese Medicine exhibiting robust collaborative engagement. Eminent author influence attributed Talley NJ Newcastle University, Australia. Clusters extensively cited papers keywords delineate status trend research. encompasses FD, anxiety, depression, sleep disorders, gastrointestinal disorders. Furthermore, timeline view map or trend-term suggested that duodenal low-grade inflammation ("duodenal eosinophilia" "mast cells") might be concern associated anxiety/depression. Employing analysis, revealed focal areas trends These insights serve valuable guidance scholars seeking delve into avenues.

Language: Английский

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Neurogenic differentiation 2 promotes inflammatory activation of macrophages in doxorubicin-induced myocarditis via regulating protein kinase D

BMC Cardiovascular Disorders, Journal Year: 2025, Volume and Issue: 25(1)

Published: March 18, 2025

Language: Английский

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Immune modulation: the key to combat SARS-CoV-2 induced myocardial injury

Frontiers in Immunology, Journal Year: 2025, Volume and Issue: 16

Published: May 14, 2025

The outbreak of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which caused the Coronavirus disease 2019 (COVID-19) pandemic, has posed significant healthcare challenges. In addition to complications, it led damage in other organs, particularly cardiovascular system. Of which, myocardial injury is increasingly recognized as a most complication, contributing high mortality. Recent research indicates pivotal role immune dysregulation mediating patients infected with SARS-CoV-2. this review, we provide comprehensive analysis mechanisms involved SARS-CoV-2-induced damage, focusing on roles key cells and molecules that contribute pathological process. Aiming at mitigating COVID-19, review immune-based treatments under evaluation preclinical clinical trials. Along talking about similarities differences resulting from SARS-CoV-2, Middle East (MERS-CoV) (SARS-CoV). This article provides unique perspective using past experiences prevent face ongoing virus mutations.

Language: Английский

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