Late isocaloric eating increases hunger, decreases energy expenditure, and modifies metabolic pathways in adults with overweight and obesity

Cell Metabolism, Journal Year: 2022, Volume and Issue: 34(10), P. 1486 - 1498.e7

Published: Oct. 1, 2022

Language: Английский

---

Circadian Rhythms Disrupted by Light at Night and Mistimed Food Intake Alter Hormonal Rhythms and Metabolism

International Journal of Molecular Sciences, Journal Year: 2023, Volume and Issue: 24(4), P. 3392 - 3392

Published: Feb. 8, 2023

Availability of artificial light and light-emitting devices have altered human temporal life, allowing 24-hour healthcare, commerce production, expanding social life around the clock. However, physiology behavior that evolved in context 24 h solar days are frequently perturbed by exposure to at night. This is particularly salient circadian rhythms, result endogenous biological clocks with a rhythm ~24 h. Circadian rhythms govern features behavior, set precisely primarily during day, though other factors, such as timing meals, can also affect rhythms. significantly affected night shift work because nocturnal light, electronic devices, shifts meals. Night workers increased risk for metabolic disorder, well several types cancer. Others who exposed or late mealtimes show disrupted cardiac disorders. It imperative understand how alter function develop strategies mitigate their negative effects. In this review, we provide an introduction physiological regulation homeostasis suprachiasmatic nucleus (SCN), SCN-mediated hormones display including melatonin glucocorticoids. Next, discuss circadian-gated processes sleep food intake, followed modern lighting disrupts molecular clock Lastly, identify disruptions metabolism increase susceptibility syndrome cardiovascular diseases, various harmful consequences associated on health.

Language: Английский

---

Timing of daily calorie loading affects appetite and hunger responses without changes in energy metabolism in healthy subjects with obesity

Cell Metabolism, Journal Year: 2022, Volume and Issue: 34(10), P. 1472 - 1485.e6

Published: Sept. 9, 2022

Language: Английский

---

Intermittent fasting plus early time-restricted eating versus calorie restriction and standard care in adults at risk of type 2 diabetes: a randomized controlled trial

Nature Medicine, Journal Year: 2023, Volume and Issue: 29(4), P. 963 - 972

Published: April 1, 2023

Language: Английский

---

Meal timing and its role in obesity and associated diseases

Frontiers in Endocrinology, Journal Year: 2024, Volume and Issue: 15

Published: March 22, 2024

Meal timing emerges as a crucial factor influencing metabolic health that can be explained by the tight interaction between endogenous circadian clock and homeostasis. Mistimed food intake, such delayed or nighttime consumption, leads to desynchronization of internal is associated with an increased risk for obesity disturbances type 2 diabetes cardiovascular diseases. Conversely, meal aligned cellular rhythms optimize performance tissues organs. In this review, we provide overview effects discuss underlying mechanisms. Additionally, explore factors timing, including determinants chronotype genetics, well external influences like social factors, cultural aspects, work schedules. This review could contribute defining meal-timing-based recommendations public initiatives developing guidelines effective lifestyle modifications targeting prevention treatment Furthermore, it sheds light on must considered in design future intervention trials.

Language: Английский

---