Trajectories of brain white matter development in young children with prenatal alcohol exposure DOI
Preeti Kar, Jess E. Reynolds, W. Ben Gibbard

et al.

Human Brain Mapping, Journal Year: 2022, Volume and Issue: 43(13), P. 4145 - 4157

Published: May 21, 2022

Abstract Prenatal alcohol exposure (PAE) is associated with alterations to brain white matter microstructure. Previous studies of PAE have demonstrated different findings in young children compared older and adolescents, suggesting altered developmental trajectories highlighting the need for longitudinal research. 122 datasets 54 (27 males) 196 89 without (45 were included this analysis. Children underwent diffusion tensor imaging between 2 8 years age, returning approximately every 6 months. Mean fractional anisotropy (FA) mean diffusivity (MD) obtained 10 major tracts examined age‐related changes using linear mixed effects models sex, group (PAE vs. control) an age‐by‐group interaction. had slower decreases MD over time genu corpus callosum, inferior fronto‐occipital fasciculus, uncinate fasciculus. No significant interactions noted FA. These show development than unexposed controls. This connects previous cross‐sectional lower higher adolescents PAE, further helps understand PAE. deviation from typical may reflect plasticity, which has implications cognitive behavioral learning

Language: Английский

Periods of synchronized myelin changes shape brain function and plasticity DOI

Omar de Faria,

Helena Pivoňková, Balázs Varga

et al.

Nature Neuroscience, Journal Year: 2021, Volume and Issue: 24(11), P. 1508 - 1521

Published: Oct. 28, 2021

Language: Английский

Citations

119
Cerebral White Matter Myelination and Relations to Age, Gender, and Cognition: A Selective Review DOI Creative Commons
Irina S. Buyanova, Marie Arsalidou

Frontiers in Human Neuroscience, Journal Year: 2021, Volume and Issue: 15

Published: July 6, 2021

White matter makes up about fifty percent of the human brain. Maturation white accompanies biological development and undergoes most dramatic changes during childhood adolescence. Despite advances in neuroimaging techniques, controversy concerning spatial, temporal patterns myelination, as well degree to which microstructural characteristics can vary a healthy brain function age, gender cognitive abilities still exists. In selective review we describe methods assessing myelination evaluate effects age nine major fiber tracts, highlighting their role higher-order functions. Our findings suggests that indices by tract, hemisphere. Effects were also identified, although some attribute differences methodological factors or social learning opportunities. Findings point further directions research will improve our understanding complex myelination-behavior relation across may have implications for educational clinical practice.

Language: Английский

Citations

107
Brodmann area 10: Collating, integrating and high level processing of nociception and pain DOI
Ke Peng,

Sarah C. Steele,

Lino Becerra

et al.

Progress in Neurobiology, Journal Year: 2017, Volume and Issue: 161, P. 1 - 22

Published: Dec. 2, 2017

Language: Английский

Citations

132
The role of experience in adolescent cognitive development: Integration of executive, memory, and mesolimbic systems DOI
Vishnu P. Murty, Finnegan J. Calabro, Beatríz Luna

et al.

Neuroscience & Biobehavioral Reviews, Journal Year: 2016, Volume and Issue: 70, P. 46 - 58

Published: July 29, 2016

Language: Английский

Citations

130
Development of Hippocampal–Prefrontal Cortex Interactions through Adolescence DOI Open Access
Finnegan J. Calabro, Vishnu P. Murty, Maria Jalbrzikowski

et al.

Cerebral Cortex, Journal Year: 2019, Volume and Issue: 30(3), P. 1548 - 1558

Published: July 30, 2019

Significant improvements in cognitive control occur from childhood through adolescence, supported by the maturation of prefrontal systems. However, less is known about neural basis refinements proceeding adolescence to adulthood. Accumulating evidence indicates that integration between hippocampus (HPC) and cortex (PFC) supports flexible cognition has a protracted maturation. Using longitudinal design (487 scans), we characterized developmental changes 8 32 years age HPC-PFC functional connectivity at rest its associations with development. Results indicated significant increases HPC ventromedial PFC (vmPFC), but not dorsolateral PFC. Importantly, HPC-vmPFC exclusively predicted performance on Stockings Cambridge task, which probes problem solving future planning. These data provide high-level into adulthood increased across vmPFC adolescence.

Language: Английский

Citations

98
White matter pathways and social cognition DOI
Yin Wang, Athanasia Metoki, Kylie H. Alm

et al.

Neuroscience & Biobehavioral Reviews, Journal Year: 2018, Volume and Issue: 90, P. 350 - 370

Published: April 20, 2018

Language: Английский

Citations

89
The emergence of empathy: A developmental neuroscience perspective DOI
Jean Decety, Claire Holvoet

Developmental Review, Journal Year: 2021, Volume and Issue: 62, P. 100999 - 100999

Published: Oct. 21, 2021

Language: Английский

Citations

71
Early deprivation alters structural brain development from middle childhood to adolescence DOI Creative Commons
Margaret A. Sheridan, Cora Mukerji, Mark Wade

et al.

Science Advances, Journal Year: 2022, Volume and Issue: 8(40)

Published: Oct. 7, 2022

Hypotheses concerning the biologic embedding of early adversity via developmental neuroplasticity mechanisms have been proposed on basis experimental studies in animals. However, no demonstrated a causal link between and neural development humans. Here, we present evidence from randomized controlled trial linking psychosocial deprivation childhood to changes cortical adolescence using longitudinal data Bucharest Early Intervention Project. Changes structure due randomization foster care were most pronounced lateral medial prefrontal cortex white matter tracts connecting parietal cortex. Demonstrating impact exposure highlights importance placement into family-based mitigate lasting neurodevelopmental consequences associated with early-life deprivation.

Language: Английский

Citations

43
Simulating the impact of white matter connectivity on processing time scales using brain network models DOI Creative Commons
Paul Triebkorn, Viktor Jirsa, Peter Ford Dominey

et al.

Communications Biology, Journal Year: 2025, Volume and Issue: 8(1)

Published: Feb. 7, 2025

The capacity of the brain to process input across temporal scales is exemplified in human narrative, which requires integration information ranging from words, over sentences long paragraphs. It has been shown that this processing distributed a hierarchy multiple areas with close sensory cortex, on faster time scale than associative cortex. In study we used reservoir computing derived connectivity investigate effect structural regions during narrative task paradigm. We systematically tested removal selected fibre bundles (IFO, ILF, MLF, SLF I/II/III, UF, AF) regions. show distance pathways such as IFO provide form shortcut whereby driven activation visual cortex can directly impact distant frontal areas. To validate our model demonstrated significant correlation predicted ordering empirical results intact/scrambled fMRI This emphasizes connectivity's role hierarchies, providing framework for future research structure and neural dynamics cognitive tasks.

Language: Английский

Citations

1
Longitudinal multimodal MRI as prognostic and diagnostic biomarker in presymptomatic familial frontotemporal dementia DOI Creative Commons
Lize C. Jiskoot, Jessica Panman, Lieke Meeter

et al.

Brain, Journal Year: 2018, Volume and Issue: 142(1), P. 193 - 208

Published: Oct. 25, 2018

Developing and validating sensitive biomarkers for the presymptomatic stage of familial frontotemporal dementia is an important step in early diagnosis design future therapeutic trials. In longitudinal Frontotemporal Dementia Risk Cohort, mutation carriers non-carriers from families with due to microtubule-associated protein tau (MAPT) progranulin (GRN) mutations underwent a clinical assessment multimodal MRI at baseline, 2-, 4-year follow-up. Of cohort 73 participants, eight (three GRN, five MAPT) developed features ('converters'). Longitudinal whole-brain measures white matter integrity (fractional anisotropy) grey volume these converters (n = 8) were compared healthy ('non-converters'; n 35) 30) same families. We also assessed prognostic performance decline within regions interest by means receiver operating characteristic analyses followed stepwise logistic regression. demonstrated lower fractional anisotropy values extensive (genu corpus callosum, forceps minor, uncinate fasciculus, superior fasciculus) smaller volumes (prefrontal, temporal, cingulate, insular cortex) over time converters, present 2 years before symptom onset. White loss right fasciculus genu callosum provided significant classifiers between non-converters, non-carriers. Converters' within-individual disease trajectories showed relatively gradual onset MAPT, whereas GRN had more rapid changes around MAPT than converters. Our study confirms presence spreading predominant pathology towards highlights value as biomarker dementia.

Language: Английский

Citations

80