Reduced tactile sensitivity is associated with mild cognitive impairment DOI Creative Commons
Annette Löffler, Florian Beier, Robin Bekrater‐Bodmann

et al.

EBioMedicine, Journal Year: 2023, Volume and Issue: 99, P. 104896 - 104896

Published: Dec. 1, 2023

Sensory impairment has been related to age-associated cognitive decline. While these associations were investigated primarily in the auditory and visual domain, other senses such as touch have rarely studied. Thus, it remains open whether results are specific for particular sensory domains, or rather point a fundamental role of deficits

Language: Английский

Exploring associations between dual sensory impairment and neuropsychiatric disorders: insights from a prospective cohort study in the UK Biobank DOI
Haihua Guo, Wei Zhang,

Shuang-Ling Han

et al.

Archives of Gerontology and Geriatrics, Journal Year: 2025, Volume and Issue: 135, P. 105865 - 105865

Published: April 18, 2025

Language: Английский

Citations

0
Hearing loss and cognitive impairment among older adults: findings from the China health and retirement longitudinal study DOI Creative Commons
Qin Zhao,

F.L. Chen,

Xiaozhen Song

et al.

BMC Public Health, Journal Year: 2025, Volume and Issue: 25(1)

Published: April 30, 2025

With the rapid aging of populations, dementia has become a major health problem. Hearing loss is common among older adults and been recognized as contributing factor to cognitive impairment dementia. We aimed explore association between hearing in adults. also sought quantify extent which impact on could be mediated by depression social isolation. used nationally representative data from China Health Retirement Longitudinal Study (CHARLS), population-based cohort study. The study population comprised aged 60 who participated at least two waves CHARLS. Cognitive function was measured based four dimensions: orientation, computation, memory, drawing. defined according self-reported data. logistic regression models analyze cross-sectional impairment. Cox proportional hazards were examine longitudinal conducted an in-depth analysis severity its associated risk Additionally, we calculated percentage excess (PERM) In total, 7891 individuals included analysis, 5326 with mean follow-up 6.38 years. after adjusting for all covariates (OR = 1.76, 95% CI: 1.49-2.08). hazard ratio compared no 1.24 (95% 1.06-1.46) adjustment demographics, socioeconomic factors, health-related behaviors. Further revealed that moderate or severe had strong relationship (HR 1.32, 1.07-1.62). Of total impairment, 20.83% 4.17% independently providing evidence addressing help improve function.

Language: Английский

Citations

0
Recent Therapeutic Progress and Future Perspectives for the Treatment of Hearing Loss DOI Creative Commons
Joey Lye, Derek S. Delaney,

Fiona K. Leith

et al.

Biomedicines, Journal Year: 2023, Volume and Issue: 11(12), P. 3347 - 3347

Published: Dec. 18, 2023

Up to 1.5 billion people worldwide suffer from various forms of hearing loss, with an additional 1.1 at risk insults such as increased consumption recreational noise-emitting devices and ageing. The most common type impairment is sensorineural loss caused by the degeneration or malfunction cochlear hair cells spiral ganglion nerves in inner ear. There currently no cure for loss. However, emerging frontier technologies gene, drug cell-based therapies offer hope effective cure. In this review, we discuss current therapeutic progress treatment We describe evaluate major approaches being applied summarize key trials studies.

Language: Английский

Citations

9
How Modifiable Are Modifiable Dementia Risk Factors? A Framework for Considering the Modifiability of Dementia Risk Factors DOI Creative Commons
Lisa Bransby, Emily Rosenich, Paul Maruff

et al.

The Journal of Prevention of Alzheimer s Disease, Journal Year: 2023, Volume and Issue: unknown

Published: Jan. 1, 2023

Many risk factors for dementia, identified from observational studies, are potentially modifiable. This raises the possibility that targeting key modifiable dementia may reduce prevalence of which has led to development reduction and prevention strategies, such as intervention trials or guidelines. However, what rarely been considered in studies inform these strategies is extent can (1) be by individuals, (2) readily modified individuals. Characteristics readiness identification targeting, well when they should targeted, influence design, success reducing risk. review aims develop a framework classifying degree modifiability research studies. The could an individual seeking their determined, resources might needed both factor modification, whether modification optimal early-life (aged <45 years), midlife 45–65 years) late-life >65 years). Finally, barriers ability engage and, ultimately, discussed.

Language: Английский

Citations

7
Reduced tactile sensitivity is associated with mild cognitive impairment DOI Creative Commons
Annette Löffler, Florian Beier, Robin Bekrater‐Bodmann

et al.

EBioMedicine, Journal Year: 2023, Volume and Issue: 99, P. 104896 - 104896

Published: Dec. 1, 2023

Sensory impairment has been related to age-associated cognitive decline. While these associations were investigated primarily in the auditory and visual domain, other senses such as touch have rarely studied. Thus, it remains open whether results are specific for particular sensory domains, or rather point a fundamental role of deficits

Language: Английский

Citations

7