Sodium selenite enhanced the selenium content in black soldier fly DOI Creative Commons
Yifan Li, Han Chen, Yunting Zhang

et al.

Research Square (Research Square), Journal Year: 2024, Volume and Issue: unknown

Published: Dec. 6, 2024

Abstract This study focuses on the effects of different levels sodium selenite growth, selenium content, and antioxidant capacity black soldier fly (Hermetia illucens). The experiment used doses for treatment. Basic diet, no supplements (control); diet plus 10mg /kg Se (Se10); 20mg (Se20); 30mg/kg (Se30); 40mg/kg (Se40). results show that addition significantly increases content improves utilization capacity(P < 0.05). However, it also negatively affects growth performance other nutrients. optimal level supplementation should be determined to balance enrichment with overall health productivity fly.

Language: Английский

Sodium selenite enhanced the selenium content in black soldier fly DOI Creative Commons
Yifan Li, Han Chen, Yunting Zhang

et al.

Scientific Reports, Journal Year: 2025, Volume and Issue: 15(1)

Published: Jan. 7, 2025

This study focuses on the effects of different levels sodium selenite growth, selenium content, and antioxidant capacity black soldier fly (Hermetia illucens). The experiment used doses for treatment, including a basic diet with no supplements (control) diets supplemented 10 mg/kg (Se10), 20 (Se20), 30 (Se30), 40 (Se40) selenite, results show that supplementation significantly increases content improves utilization (P < 0.05). However, it also negatively affects growth performance other nutrients. optimal level depends ration enrichment overall health productivity fly.

Language: Английский

Citations

1
Trends and recent progresses of selenium nanoparticles as novel autophagy regulators for therapeutic development DOI Creative Commons
Dongsheng Chen,

Hongmei Lu,

Yuhe Ma

et al.

Frontiers in Nutrition, Journal Year: 2023, Volume and Issue: 10

Published: Feb. 2, 2023

Autophagy, one of the major intracellular degradation systems, plays an important role in maintaining normal cellular physiological functions and protecting organisms from different diseases. Selenium (Se), essential trace element, is involved many metabolic regulatory signaling events a key human health. In recent years, selenium nanoparticles (Se NPs) have attracted increasing attentions biomedical field due to their low toxicity, high bioavailability bioactivity. Taking advantage advanced biological activities, Se NPs can be used alone as potential therapeutic agents, or combine with other agents served carriers for development novel therapeutics. More interestingly, been widely reported affect autophagy signaling, which therefor allow against Here, this review suggested relationships between autophagy, followed by trends progresses regulation diseased conditions. importantly, work discussed roles mechanisms regulating, might enhance our understanding about how regulate disease treatment. This expected promote application regulators, benefit associated

Language: Английский

Citations

11
Golgi apparatus regulated pyroptosis through the miR-32-5p/Golga7/NLRP3 axis in chicken splenic lymphocytes exposure to ammonia DOI

Jiahao Liu,

Haifeng Liu,

Haojinming Tang

et al.

Environmental Pollution, Journal Year: 2024, Volume and Issue: unknown, P. 124923 - 124923

Published: Sept. 1, 2024

Language: Английский

Citations

4
Cross-Talk Between Selenium Nanoparticles and Cancer Treatment Through Autophagy DOI

Waseem Ali,

Yan Chen, Jameel Ahmed Gandahi

et al.

Biological Trace Element Research, Journal Year: 2023, Volume and Issue: 202(7), P. 2931 - 2940

Published: Oct. 10, 2023

Language: Английский

Citations

10
A new therapy to alleviate the inflammatory injury of piglet intestine caused by short-distance transportation——music DOI Creative Commons

Qin Fu,

Bin Bai,

Sitong Zhou

et al.

PLoS ONE, Journal Year: 2025, Volume and Issue: 20(2), P. e0313354 - e0313354

Published: Feb. 25, 2025

The purpose of this study was to explore whether music can reduce stress in animals by regulating the activity hypothalamus pituitary adrenal cortex (HPA) axis and reducing concentration cortisol. control group not played with any or mechanical noise, before during transport, noise transport as a positive control. results showed that after two-hours transportation, concentrations adrenocorticotropic hormone cortisol were lower than groups, while level higher groups. Plasma D-lactic acid diamine oxidase those group, group. In addition, jejunal inflammatory factors interleukin-6 interleukin-8 but there no difference interleukin-12 three However, significant Illinois-6, Illinois-12 INF-γ between contents reactive oxygen species, malondialdehyde glutathione peroxidase had changes compared species content decreased. Compared differently expressed genes analysis also mRNA expression jejunum group’ piglets some Kyoto Encyclopedia Genes Genomes (KEGG) pathways related inflammation highly conclusion, our musical stimulation response caused transportation HPA axis. Noise increased axis, which aggravated intestinal damage oxidative

Language: Английский

Citations

0
Alleviating effects of selenium on fluoride-induced testosterone synthesis disorder and reproduction toxicity in rats DOI
Hui Zhao,

Yaya Zhu,

Yangfei Zhao

et al.

Ecotoxicology and Environmental Safety, Journal Year: 2022, Volume and Issue: 247, P. 114249 - 114249

Published: Oct. 30, 2022

Language: Английский

Citations

12
Low selenium and T-2 toxin may be involved in the pathogenesis of Kashin-Beck disease by affecting AMPK/mTOR/ULK1 pathway mediated autophagy DOI Creative Commons
Huan Deng, Xue Lin, Rongqi Xiang

et al.

Ecotoxicology and Environmental Safety, Journal Year: 2024, Volume and Issue: 279, P. 116503 - 116503

Published: May 28, 2024

Kashin-Beck disease (KBD) is an endemic, environmentally associated cartilage disease. Previous studies have shown that the environmental suspected pathogenic factors of KBD, T-2 toxin and low selenium, are involved in regulation inflammation, oxidative stress autophagy some tissues organs. In diseases, level cellular determines fate chondrocytes. However, whether KBD lesions, role selenium toxins injury still unclear. This work took classical AMPK/mTOR/ULK1 regulatory pathway as entry point to clarify relationship between chondrocyte autophagy. Transmission electron microscopy was used observe chondrocytes patients. qRT-PCR western blot were analyze expression markers. The rat model established by toxin, detected after 4- 12-week interventions. Chondrocyte found down-regulated. model, showed up-regulated trend when treated for a short time or concentration, increased. long at high concentrations, down-regulated trend, reduced even defective. conclusion, process lesion, may increase early stage, decrease late stage with progression lesion. Low affect pathway.

Language: Английский

Citations

2
Selenium Mitigates Ammonia-Induced Neurotoxicity by Suppressing Apoptosis, Immune Imbalance, and Gut Microbiota-Driven Metabolic Disturbance in Fattening Pigs DOI Open Access

Yutao Li,

Jing Wang,

Houjuan Xing

et al.

Biological Trace Element Research, Journal Year: 2022, Volume and Issue: 201(7), P. 3341 - 3355

Published: Oct. 13, 2022

Language: Английский

Citations

8
Selenium participates in the formation of kidney stones by alleviating endoplasmic reticulum stress and apoptosis of renal tubular epithelial cells DOI Creative Commons
Xiaozhe Su, Hongbo Chen, Heng Xiang

et al.

Redox Report, Journal Year: 2024, Volume and Issue: 29(1)

Published: Oct. 16, 2024

To investigate the role of selenium and selenium-containing proteins in etiology pathogenesis kidney stones.

Language: Английский

Citations

1
Role of selenium in cell death DOI
Peng Gao, Chenzhi Wang, Jiali Xu

et al.

journal of nutritional oncology, Journal Year: 2023, Volume and Issue: 8(2), P. 94 - 100

Published: June 1, 2023

Abstract Selenium is an essential nutrient closely related to redox homeostasis in the body. A imbalance will adversely affect microenvironment inside and outside cell, leading cell death. Various types of death have been discovered recent years, but role(s) selenium associated mechanism(s) action require further elaboration. We review roles mechanisms necrosis, apoptosis, ferroptosis, autophagy, pyroptosis. Under normal conditions, inhibits pyroptosis by downregulating nuclear factor κB pathway, upregulating antiapoptotic proteins, decreasing oxidative stress, increasing antioxidant enzyme activity, enhancing mTOR NLRP3/caspase-1 thereby helping maintain physiological functions cells. On other hand, deficiency leads activation PI3K/AKT Notch/Hes1 pathways, causing a significant increase level stress organism, resulting In case malignancy, vivo metabolite inorganic selenium, hydrogen selenide, plays antitumor role inducing apoptosis ferroptosis tumor cells because its high activity. conclusion, adequate body for maintaining cellular reducing fibrotic alterations. Furthermore, metabolites may some clinical value therapy.

Language: Английский

Citations

3