Modulation of Autophagy in Gastric Cancer Cells and Sensitization to 5-Fluorouracil by Combination Therapy with Se–FA Nanoparticles DOI
Elnaz Faghfuri, Shahnaz Hosseinzadeh, Amir Hossein Faghfouri

et al.

Journal of Cluster Science, Journal Year: 2023, Volume and Issue: 35(4), P. 975 - 982

Published: Dec. 14, 2023

Language: Английский

Selenium Mitigates Caerulein and LPS-induced Severe Acute Pancreatitis by Inhibiting MAPK, NF-κB, and STAT3 Signaling via the Nrf2/HO-1 Pathway DOI

K Swetha,

Mylanayakanahosahalli Chandrashekar Indumathi,

R Sanchit Kishan

et al.

Biological Trace Element Research, Journal Year: 2025, Volume and Issue: unknown

Published: Feb. 5, 2025

Language: Английский

Citations

2
Combined effect of mercury and ammonia toxicity and its mitigation using selenium nanoparticles in fish DOI

A.A. SHINDE,

Rajesh Sharma,

Prem Kumar

et al.

Aquatic Toxicology, Journal Year: 2025, Volume and Issue: 280, P. 107270 - 107270

Published: Feb. 7, 2025

Language: Английский

Citations

1
Cascade Targeting Selenium Nanoparticles-Loaded Hydrogel Microspheres for Multifaceted Antioxidant Defense in Osteoarthritis DOI
Jiacheng Liu, Junyan Liu, Senrui Liu

et al.

Biomaterials, Journal Year: 2025, Volume and Issue: 318, P. 123195 - 123195

Published: Feb. 15, 2025

Language: Английский

Citations

1
Construction and anti-pancreatic cancer activity of selenium nanoparticles stabilized by Prunella vulgaris polysaccharide DOI
Shihai Zhang, Yang Wang, Meiqin Wang

et al.

International Journal of Biological Macromolecules, Journal Year: 2024, Volume and Issue: 278, P. 134924 - 134924

Published: Aug. 22, 2024

Language: Английский

Citations

7
Astrocyte modulation in cerebral ischemia-reperfusion injury: A promising therapeutic strategy DOI
Ziyu Wang, Xiaolu Zhang, Guangming Zhang

et al.

Experimental Neurology, Journal Year: 2024, Volume and Issue: 378, P. 114814 - 114814

Published: May 16, 2024

Language: Английский

Citations

5
Selenium pretreatment improve renal function, autophagy signaling pathway and mir21a gene expression in renal ischemia reperfusion injury model in male rat DOI

Fatemeh Ayari,

Amin Abdollahzade Fard, Leila Chodari

et al.

Journal of Trace Elements in Medicine and Biology, Journal Year: 2025, Volume and Issue: 88, P. 127610 - 127610

Published: Feb. 8, 2025

Language: Английский

Citations

0
Paclitaxel-Ang-2-functionalized bionic mesoporous selenium nanoparticles for targeted therapy of glioma DOI Creative Commons
Huan Shi,

Biaobiao Wang,

Zhiwei Shi

et al.

Pharmacological Research, Journal Year: 2025, Volume and Issue: 216, P. 107783 - 107783

Published: May 15, 2025

Glioma, the most prevalent primary intracranial tumor, presents significant clinical treatment challenges due to its high invasiveness and therapeutic resistance. Therefore, development of a targeted agent that is both highly effective low in toxicity crucial. In this research, we aimed design bionic mesoporous selenium nanoparticle (ACMLMSeP) functionalized with paclitaxel Ang-2 for nasal administration as approach glioma. Nasal facilitates direct delivery drugs brain through olfactory nerve, thereby circumventing protective mechanisms blood-brain barrier. Mesoporous (MSe) significantly enhances loading capacity insoluble while improving their water solubility. The functionalization MSe enables slow drug release accumulation. Moreover, accumulated nano-selenium promotes reactive oxygen species (ROS) production, induces autophagy, synergizes accelerate apoptosis tumor cells. Analysis using Transmission Electron Microscopy (TEM) images Dynamic Light Scattering (DLS) indicated ACMLMSe has an average particle size roughly 135 nm. Results from vitro assessments ACMLMSeP sustained drug, reaching total rate 74.96 ± 2.34 % within 24 h. Cellular uptake studies vivo imaging showed strong targeting capabilities nanoparticles. Furthermore, results obtained MTT assays, flow cytometry analysis, immunofluorescence staining, antitumor evaluations collectively revealed effectively inhibited proliferation promoting C6 summary, these experimental findings clearly suggest may serve promising biomimetic nanosystem

Language: Английский

Citations

0
Rod and spherical selenium nanoparticles: Physicochemical properties and effects on red blood cells and neutrophils DOI
И. В. Горудко, D. V. Grigorieva,

Г. А. Гусаков

et al.

Biochimica et Biophysica Acta (BBA) - General Subjects, Journal Year: 2025, Volume and Issue: 1869(5), P. 130777 - 130777

Published: Feb. 19, 2025

Language: Английский

Citations

0
Green Synthesis of Selenium Nanoparticles Utilizing Drimia indica: Insights Into Anticancer and Antimicrobial Activities DOI

Fuad Ameen,

Norah Salem Almalki,

Rawan M. Alshalan

et al.

Microscopy Research and Technique, Journal Year: 2024, Volume and Issue: unknown

Published: Nov. 18, 2024

Selenium nanoparticles (SeNPs) have garnered significant interest as anticancer and antimicrobial agents. The aqueous extract of medicinal plant Drimia indica leaves (DI-LAE) was used to synthesize SeNPs (DI-SeNPs) that were extensively characterized by UV-visible absorbance, TEM, EDX, XRD, zeta potential measurements, FTIR. DI-SeNPs exhibited dose-dependent toxicity against the human lung adenocarcinoma cell line (A549; IC

Language: Английский

Citations

2
Modified Titanium Surface with Nano Amorphous Calcium Phosphate@Chitosan Oligolactate as Ion Loading Platform with Multifunctional Properties for Potential Biomedical Application DOI
Marijana R. Pantović Pavlović, Nenad Ignjatović, Senka Gudić

et al.

Annals of Biomedical Engineering, Journal Year: 2024, Volume and Issue: 52(8), P. 2221 - 2233

Published: April 25, 2024

Language: Английский

Citations

1