Genistein protects benzotriazole ultraviolet stabilizer UV-234-induced hepatotoxicity by modulating ROS/Nrf2 and NF-κB signaling in yellow catfish (Pelteobagrus fulvidraco) DOI
Siwen Li, Jiaqi Xie, Xinlian Li

et al.

Comparative Biochemistry and Physiology Part C Toxicology & Pharmacology, Journal Year: 2023, Volume and Issue: 271, P. 109675 - 109675

Published: June 1, 2023

Language: Английский

Molecular mechanism of kidney damage caused by abamectin in carp: Oxidative stress, inflammation, mitochondrial damage, and apoptosis DOI
Xinyu Wu,

Yeyun Ma,

Xueqing Li

et al.

Toxicology, Journal Year: 2023, Volume and Issue: 494, P. 153599 - 153599

Published: July 25, 2023

Language: Английский

Citations

25

Signalling regulation of reactive oxygen species in fish inflammation DOI
Feng Gao, Yanjing Zhao, Xiaowei Shi

et al.

Reviews in Aquaculture, Journal Year: 2024, Volume and Issue: 16(3), P. 1266 - 1285

Published: Jan. 29, 2024

Abstract Reactive oxygen species (ROS), which are key cellular signalling molecules, reactive chemicals containing oxygen. Cell survival or death is a critical issue in the inflammatory response. Accumulation of ROS involves generation and scavenging, determine homeostasis. Understanding roles modulating response fish vital for helping protect from damage water pollutants harsh environmental conditions. ROS‐related genes pathways relatively conserved but vary among different species. Recent frequent incidences diseases have posed considerable challenge to large‐scale aquaculture. important stress perception, integration diverse stress‐responsive networks, activation animal defence mechanisms, frequently occur during inflammation fish. This review summarises recent studies on Furthermore, it examines relationship between may contribute understanding underlying mechanisms by regulate provide suggestions sustainable development

Language: Английский

Citations

7

Silybin mitigated liver and brain damage after difenoconazole exposure: Crosstalk between oxidative stress, inflammation, ferroptosis and apoptosis DOI
Xinyu Wu, Jiawei Chen,

Kaixin Ping

et al.

Pesticide Biochemistry and Physiology, Journal Year: 2024, Volume and Issue: 202, P. 105942 - 105942

Published: May 6, 2024

Language: Английский

Citations

5

Crosstalk of oxidative stress, inflammation, apoptosis, and autophagy under reactive oxygen stress involved in difenoconazole-induced kidney damage in carp DOI
Xinyu Wu, Baoshi Xu,

Huizhen Chen

et al.

Fish & Shellfish Immunology, Journal Year: 2022, Volume and Issue: 132, P. 108508 - 108508

Published: Dec. 27, 2022

Language: Английский

Citations

23

Difenoconazole disrupts carp intestinal physical barrier and causes inflammatory response via triggering oxidative stress and apoptosis DOI
Xinyu Wu,

Hairui Han,

Kunmei Xie

et al.

Pesticide Biochemistry and Physiology, Journal Year: 2023, Volume and Issue: 194, P. 105507 - 105507

Published: June 24, 2023

Language: Английский

Citations

13

Mechanisms regarding respiratory toxicity triggered by accumulation of ROS in carp exposed to difenoconazole DOI

Huimiao Feng,

Huizhen Chen,

Jingchao Qiang

et al.

Pesticide Biochemistry and Physiology, Journal Year: 2023, Volume and Issue: 191, P. 105343 - 105343

Published: Jan. 14, 2023

Language: Английский

Citations

12

Immunoprotective effect of silybin through blocking p53-driven caspase-9-Apaf-1-Cyt c complex formation and immune dysfunction after difenoconazole exposure in carp spleen DOI

Enzhuang Pan,

Xin Yue, Xueqing Li

et al.

Environmental Science and Pollution Research, Journal Year: 2024, Volume and Issue: 31(13), P. 19396 - 19408

Published: Feb. 15, 2024

Language: Английский

Citations

5

Triazole pesticides exposure impaired steroidogenesis associated to an increase in AHR and CAR expression in testis and altered sperm parameters in chicken DOI Creative Commons
Loïse Serra,

Guillaume Bourdon,

Anthony Estienne

et al.

Toxicology Reports, Journal Year: 2023, Volume and Issue: 10, P. 409 - 427

Published: Jan. 1, 2023

Since several decades, we observe the decline of various bird populations that could be partly linked to agricultural intensification and use large amount pesticides. Even if triazoles compounds are most widely used fungicides, their effects on reproductive parameters in birds not clearly known. In present study, investigated vitro 8 alone (propiconazole (PP, from 0 10 µM), prothioconazole (PT), epoxiconazole (Epox), tetraconazole (TT), tebuconazole (TB), difenoconazole (Dif), cyproconazole (Cypro), metconazole (MC) (from 1 mM)) male chicken functions by using testis explants, primary Sertoli cells sperm samples. testis, all at higher concentrations for 48 h inhibited lactate testosterone secretion mostly association with reduced expression HSD3B and/or STAR mRNA levels. These data were also associated increased nuclear receptors Aryl Hydrocarbon Receptor (AHR) Constitutive Androstane (CAR) levels except PP a reduction cell viability. When focusing parameters, demonstrated (MC, Epox, Dif, TB, TT Cypro) 0.1 or mM either 2, 12 24 min exposure decreased motility velocity percentage spermatozoa abnormal morphology. At opposite, dose dependent manner after 2 whereas no significant effect was observed response PT whatever time exposure. Moreover, these an increase production reactive oxygen species spermatozoa. Taken together, impair steroidogenesis semen potentially through AHR CAR oxidative stress, respectively.All will available.

Language: Английский

Citations

9

Quercetin alleviates the toxicity of difenoconazole to the respiratory system of carp by reducing ROS accumulation and maintaining mitochondrial dynamic balance DOI
Xiaomeng Ji, Jiajia Guo,

Yeyun Ma

et al.

Toxicology and Applied Pharmacology, Journal Year: 2024, Volume and Issue: 484, P. 116860 - 116860

Published: Feb. 10, 2024

Language: Английский

Citations

3

Quercetin alleviates difenoconazole-induced growth inhibition in carp through intestinal-brain axis DOI

Huimiao Feng,

Kaixin Ping,

Yue Yang

et al.

Pesticide Biochemistry and Physiology, Journal Year: 2024, Volume and Issue: 204, P. 106066 - 106066

Published: July 30, 2024

Language: Английский

Citations

3