Precision Meets Repurposing: Innovative Approaches in Human Papillomavirus and Epstein-Barr Virus-Driven Cancer Therapy DOI Creative Commons
Queenie Fernandes

Cancer Letters, Journal Year: 2024, Volume and Issue: 607, P. 217318 - 217318

Published: Nov. 8, 2024

Language: Английский

Serious Long-Term Effects of Head and Neck Cancer from the Survivors’ Point of View DOI Open Access
Kathy Taylor, Cecilie Delphin Amdal, Kristin Bjordal

et al.

Healthcare, Journal Year: 2023, Volume and Issue: 11(6), P. 906 - 906

Published: March 21, 2023

The long-term problems of head and neck cancer survivors (HNCS) are not well known. In a cross-sectional international study aimed at exploring the quality life in this population, 1114 HNCS were asked to state their two most serious effects. A clinician recorded responses during face-to-face appointments. list 15 example was provided, but free text field also available. total 1033 responded question. frequent 'dry mouth' (DM) (n = 476; 46%), 'difficulty swallowing/eating' (DSE) 408; 40%), 'hoarseness/difficulty speaking' (HDS) 169; 16%), 'pain neck' (PHN) 142; 14%). 5% reported no problems. Logistic regression adjusted for age, gender, treatment, tumor stage site showed increased odds reporting DM DSE chemo-radiotherapy (CRT) alone compared surgery (odds ratio (OR): 4.7, 95% confidence interval (CI): 2.5-9.0; OR: 2.1, CI: 1.1-3.9), decreased HDS PHN (OR: 0.3, 0.1-0.6; 0.2, 0.1-0.5). Survivors with UICC IV diagnosis I had 1.9, 1.2-3.0). Laryngeal reduced oropharynx 0.4, 0.3-0.6) 7.2, 4.3-12.3). This provides evidence among HNCS.

Language: Английский

Citations

14

Self-perception of oropharyngeal cancer patients regarding the impacts of chemoradiotherapy treatments on swallowing and voice functions DOI
Daniela de Oliveira Vieira, Sofia Barreira, Mário Dinis‐Ribeiro

et al.

Revista de Logopedia Foniatría y Audiología, Journal Year: 2025, Volume and Issue: 45(2), P. 100518 - 100518

Published: Feb. 19, 2025

Language: Английский

Citations

0

Swallowing exercises for head and neck cancer patients: A systematic review and meta-analysis of randomized control trials DOI
Kondwani Joseph Banda, Hsin Chu,

Ching-Chiu Kao

et al.

International Journal of Nursing Studies, Journal Year: 2020, Volume and Issue: 114, P. 103827 - 103827

Published: Nov. 11, 2020

Language: Английский

Citations

37

Considerations for study design in the DAHANCA 35 trial of protons versus photons for head and neck cancer DOI Creative Commons
Jeppe Friborg, Kenneth Jensen, Jaran Eriksen

et al.

Radiotherapy and Oncology, Journal Year: 2023, Volume and Issue: 190, P. 109958 - 109958

Published: Oct. 21, 2023

Proton radiotherapy offers a dosimetric advantage compared to photon therapy in sparing normal tissue, but the clinical evidence for toxicity reductions treatment of head and neck cancer is limited. The Danish Head Neck Cancer Group (DAHANCA) has initiated DAHANCA 35 randomised trial clarify value proton (NCT04607694). performed an enriched population patients selected by anticipated benefit reduce risk late dysphagia or xerostomia based on tissue complication probability (NTCP) modelling. We present our considerations design test selection procedure conducted before initiating study.

Language: Английский

Citations

12

Precision Meets Repurposing: Innovative Approaches in Human Papillomavirus and Epstein-Barr Virus-Driven Cancer Therapy DOI Creative Commons
Queenie Fernandes

Cancer Letters, Journal Year: 2024, Volume and Issue: 607, P. 217318 - 217318

Published: Nov. 8, 2024

Language: Английский

Citations

4