Advanced Healthcare Materials,
Journal Year:
2024,
Volume and Issue:
13(27)
Published: June 27, 2024
Abstract
Cardiovascular
diseases
(CVDs)
are
the
leading
cause
of
mortality
worldwide
and
represent
a
pressing
clinical
need.
Vascular
occlusions
predominant
CVD
necessitate
surgical
interventions
such
as
bypass
graft
surgery
to
replace
damaged
or
obstructed
blood
vessel
with
synthetic
conduit.
Synthetic
small‐diameter
vascular
grafts
(sSDVGs)
desired
vessels
an
inner
diameter
<6
mm
yet
have
limited
use
due
unacceptable
patency
rates.
The
incorporation
biophysical
cues
topography
onto
sSDVG
biointerface
can
be
used
mimic
cellular
microenvironment
improve
outcomes.
In
this
review,
utility
surface
in
design
is
discussed.
First,
primary
challenges
that
sSDVGs
face
rationale
for
utilizing
biomimetic
introduced.
current
literature
surrounding
effects
topographical
on
cell
behavior
vitro
reviewed,
providing
insight
into
which
features
optimal
application
sSDVGs.
results
studies
utilized
topographically‐enhanced
vivo
evaluated.
Current
barriers
translation
Based
wealth
evidence
detailed
here,
substrate
offers
enormous
potential
outcome
provide
therapeutic
solutions
CVDs.
Heliyon,
Journal Year:
2023,
Volume and Issue:
9(9), P. e19933 - e19933
Published: Sept. 1, 2023
Spinal
cord
injury
(SCI)
is
characterized
by
damage
resulting
in
dysfunction
of
the
spinal
cord.
Hydrogels
are
common
biomaterials
that
play
an
important
role
treatment
SCI.
biocompatible,
and
some
have
electrical
conductivity
compatible
with
tissues.
a
high
drug-carrying
capacity,
allowing
them
to
be
used
for
SCI
through
loading
various
types
active
substances,
drugs,
or
cells.
We
first
discuss
basic
anatomy
physiology
human
briefly
its
treatment.
Then,
we
describe
different
strategies
further
crosslinking
classification
hydrogels
detail
hydrogel
prepared
using
processing
methods
Finally,
analyze
future
applications
limitations
The
development
opens
up
new
possibilities
options
Thus,
our
findings
will
inspire
scholars
related
fields
promote
therapy
Smart Medicine,
Journal Year:
2023,
Volume and Issue:
2(4)
Published: Oct. 27, 2023
Hearing
impairment
is
a
global
health
problem
that
affects
social
communications
and
the
economy.
The
damage
loss
of
cochlear
hair
cells
spiral
ganglion
neurons
(SGNs)
as
well
degeneration
neurites
SGNs
are
core
causes
sensorineural
hearing
loss.
Biotechnologies
biomedical
engineering
technologies
provide
new
hope
for
treatment
auditory
diseases,
which
utilizes
biological
strategies
or
tissue
methods
to
achieve
drug
delivery
regeneration
cells,
tissues,
even
organs.
Here,
advancements
in
applications
biotechnologies
(including
gene
therapy
organoids)
delivery,
electrode
coating,
electrical
stimulation
bionic
scaffolds)
field
reconstruction
presented.
Moreover,
we
summarize
challenges
perspective
on
this
field.
Aggregate,
Journal Year:
2023,
Volume and Issue:
5(2)
Published: Nov. 22, 2023
Abstract
Colloidal
crystals
are
materials
self‐assembled
from
the
colloidal
nanoparticles.
Due
to
ordered
microstructure,
they
exhibit
significant
optical
properties
and
have
shown
huge
potential
in
field
of
biosensing.
Besides,
unique
macroscopic
shapes
can
also
play
a
critical
role
sensing
process.
Here,
we
present
comprehensive
discussion
on
crystal‐based
biosensors
with
different
topological
shapes,
including
development
strategies
currently
reported
crystal
particles,
films,
fibers,
their
recent
progress
In
addition,
faced
challenges
possible
solutions
concluded
discussed.
We
expect
this
review
enrich
knowledge
encourage
communication
interdisciplinary
researchers,
thus
promoting
further
practical
applications
biosensors.
Current Organic Chemistry,
Journal Year:
2024,
Volume and Issue:
28(15), P. 1190 - 1214
Published: May 15, 2024
Abstract:
The
usage
of
nanoparticles
in
tissue
engineering
applications
has
increased
significantly
the
last
several
years.
Functional
tissues
are
developed
by
regulating
cell
proliferation,
differentiation,
and
migration
on
nanostructured
scaffolds
containing
cells.
These
provide
an
environment
that
is
more
structurally
supportive
than
microarchitecture
natural
bone.
Given
its
exceptional
properties,
such
as
osteogenic
potential,
biocompatibility,
biodegradability,
chitosan
a
good
promising
biomaterial.
Unfortunately,
chitosan's
low
mechanical
strength
makes
it
unsuitable
for
load-bearing
applications.
By
mixing
with
other
biomaterials,
this
drawback
might
be
mitigated.
Bone
uses
both
bioresorbable
materials
like
tricalcium
phosphate
bioactive
hydroxyapatite
bioglass.
Alumina
titanium
examples
bioinert
part
these
bioceramics.
When
produced
at
nanoscale
scales,
have
larger
surface
area
better
adhesion.
This
review
paper
will
go
into
great
detail
bioinert,
bioresorbable,
nanoceramics-reinforced
bone
engineering.
Advanced Healthcare Materials,
Journal Year:
2024,
Volume and Issue:
13(27)
Published: June 27, 2024
Abstract
Cardiovascular
diseases
(CVDs)
are
the
leading
cause
of
mortality
worldwide
and
represent
a
pressing
clinical
need.
Vascular
occlusions
predominant
CVD
necessitate
surgical
interventions
such
as
bypass
graft
surgery
to
replace
damaged
or
obstructed
blood
vessel
with
synthetic
conduit.
Synthetic
small‐diameter
vascular
grafts
(sSDVGs)
desired
vessels
an
inner
diameter
<6
mm
yet
have
limited
use
due
unacceptable
patency
rates.
The
incorporation
biophysical
cues
topography
onto
sSDVG
biointerface
can
be
used
mimic
cellular
microenvironment
improve
outcomes.
In
this
review,
utility
surface
in
design
is
discussed.
First,
primary
challenges
that
sSDVGs
face
rationale
for
utilizing
biomimetic
introduced.
current
literature
surrounding
effects
topographical
on
cell
behavior
vitro
reviewed,
providing
insight
into
which
features
optimal
application
sSDVGs.
results
studies
utilized
topographically‐enhanced
vivo
evaluated.
Current
barriers
translation
Based
wealth
evidence
detailed
here,
substrate
offers
enormous
potential
outcome
provide
therapeutic
solutions
CVDs.
