Silver Nanoparticles: Biomedical Applications and Future Perspectives DOI Open Access

S. Ranjbar,

Ameneh Bakhtiari,

Negin Khosravi

et al.

Journal of Composites and Compounds, Journal Year: 2024, Volume and Issue: 6(20)

Published: Sept. 30, 2024

Language: Английский

Advancements in Wound Dressing Materials: Highlighting Recent Progress in Hydrogels, Foams, and Antimicrobial Dressings DOI Creative Commons

A. S. Alberts,

Dana-Ionela Tudorache,

Adelina-Gabriela Niculescu

et al.

Gels, Journal Year: 2025, Volume and Issue: 11(2), P. 123 - 123

Published: Feb. 7, 2025

Recent advancements in wound dressing materials have significantly improved acute and chronic management by addressing challenges such as infection control, moisture balance, enhanced healing. Important progress has been made, especially with hydrogels, foams, antimicrobial for creating optimized dressings. Hydrogels are known maintaining optimal levels, while foam dressings excellent exudate absorbents. Meanwhile, incorporates various agents to reduce risks. These options healing time focusing on customized patient needs. Therefore, this review highlights the newest research prototypes applications, emphasizing their particular benefits clinical importance. Innovations stimuli-responsive hydrogels hybrid bioengineered composites discussed relation properties, including responsiveness pH, temperature, glucose, or enzymes drug delivery precision. Moreover, ongoing trials included, demonstrating potential of emerging solutions be soon translated from laboratory settings. By discussing interdisciplinary approaches that integrate advanced materials, nanotechnology, biological insights, work provides a contemporary framework patient-centric, efficient care strategies.

Language: Английский

Citations

7
Silver Nanoparticles (AgNPs): Comprehensive Insights into Bio/Synthesis, Key Influencing Factors, Multifaceted Applications, and Toxicity─A 2024 Update DOI Creative Commons

Abhinav Sati,

Tanvi N. Ranade,

Suraj N. Mali

et al.

ACS Omega, Journal Year: 2025, Volume and Issue: unknown

Published: Feb. 18, 2025

Silver nanoparticles (AgNPs) are widely recognized for their unique optical, electronic, and antibacterial properties, enabling use in biosensing, photonics, electronics, drug delivery, antimicrobial treatments. Green chemistry-based biological synthesis methods offer an eco-friendly alternative to traditional chemical techniques. Among metallic (NPs) metal oxides, those derived from plant extracts exhibit notable medicinal properties. Due exceptional stability low reactivity, AgNPs particularly well-suited various applications. can be synthesized through chemical, physical, or methods, each with distinct benefits challenges. Chemical physical approaches often involve complex purification, reactive reagents, high energy demands, while though slower, provide sustainable solutions. The chosen method strongly influences the stability, size, purity of resulting NPs. This review emphasizes importance selecting appropriate optimize characteristics functionality silver It consolidates research spanning past two decades, including most recent findings 2024. A comprehensive electronic search databases such as PubMed, Scopus, ScienceDirect, Cochrane, Google Scholar was conducted up-to-date overview advances applications nanoparticles.

Language: Английский

Citations

1
Biosynthesis of silver nanoparticles by Talaromyces funiculosus for therapeutic applications and safety evaluation DOI Creative Commons

Bahig A. El deeb,

Gerges G. Faheem,

Mahmoud S. Bakhit

et al.

Scientific Reports, Journal Year: 2025, Volume and Issue: 15(1)

Published: April 21, 2025

Abstract The study investigated the capacity of endophytic fungus Talaromyces funiculosus to biosynthesize extracellular AgNPs and assess their safety. was identified through morphological phylogenetic analyses. biosynthesized were spherical crystalline, stable (6 months), mono-dispersed (PDI: 0.007), exhibiting SPR at 422.5 nm, average diameter 34.32 Zeta potential -18.41 mV. optimal biosynthesis conditions are 1 mM AgNO 3 , 5 g biomass, pH 5.5, a reaction temperature 60 °C. Escherichia coli (bacterial strains) Candida tropicalis (yeast exhibited highest susceptibility with inhibition zones 26.3 mm 22.3 mm, respectively, 50 µg/mL AgNPs, MICs 3.7 6.3 µg/mL, respectively. cytotoxicity IC values 48.11 ppm for HEK-293 35.88 Hep-G2 cells, showing selective toxicity toward cancer cells. They demonstrated antioxidant activity by increasing GSH (10.29 14.76 mmol/g) reducing MDA (40.57 26.28 nmol/ml) ppm. also enhanced IL-10 production (96.47 177.0 pg/mL) reduced TNF-α levels (55.77 41.06 pg/mL), indicating anti-inflammatory properties. These results support safe use low-dose however, further studies needed evaluate clinical uses.

Language: Английский

Citations

1
Advancing nanomaterial synthesis: Harnessing green chemistry for sustainable innovation DOI Creative Commons
Maycon Lucas de Oliveira,

Leticia Miranda Rodrigues,

Márcia Andréia Mesquita Silva da Veiga

et al.

Green Analytical Chemistry, Journal Year: 2024, Volume and Issue: 11, P. 100148 - 100148

Published: Sept. 3, 2024

Language: Английский

Citations

5
Application of Gelatin/Vanillin/Fe3+/AGP–AgNPs Hydrogels Promotes Wound Contraction, Enhances Dermal Growth Factor Expression, and Minimizes Skin Irritation DOI Creative Commons
Sarawut Lapmanee, Sakkarin Bhubhanil, Mattaka Khongkow

et al.

ACS Omega, Journal Year: 2025, Volume and Issue: unknown

Published: March 4, 2025

This study further investigates the potential of gelatin-based hydrogel cross-linked with vanillin and ferric ion (GVF), combined andrographolide (AGP) silver nanoparticles (AgNPs), as an anti-infection biomaterial for wound dressing, aimed at exploring mechanisms that attenuate inflammation, enhance healing rates, address allergic skin irritation. AGP-AgNPs were evaluated cytotoxicity in human adult epidermal keratinocytes (HEKa) murine macrophage cell line (RAW 264.7), well nitric oxide (NO) production response to lipopolysaccharide-induced inflammation RAW 264.7 cells. Skin-wound specimens from male Wistar rats histologically analyzed thickness inflammatory changes. The mRNA expression profiling dermal growth factors was assessed using RT-qPCR, irritation tests conducted female New Zealand rabbits. These exhibited significantly lower toxicity HEKa no 264.7. Interestingly, specific concentrations produced NO control cells but more effective reducing levels pretreated lipopolysaccharides, suggesting AGP-AgNP composites are safe effectively diminish inflammation. Furthermore, a marked increase reduction histological sites observed treated AGP-AgNPs/GVF hydrogels over 21 days. Upregulation genes promoting healing, including collagen types I III, factor, transforming factor-beta, fibronectin, vascular endothelial not fibroblast time-dependent manner. results suggest anti-inflammatory properties GVF/AGP-AgNP could promote epithelialization, cellular proliferation, support extracellular matrix synthesis, facilitate angiogenesis. Additionally, rabbit contact consistently displayed reduced erythema edema, swelling, standardized scoring system yielded low primary indices this hydrogel. findings novel possess anti-inflammatory-like activity can modulate healing. leads irritation, making formulation potentially suitable topical applications care. However, comprehensive studies clinical trials should be required future.

Language: Английский

Citations

0
Enhanced antibacterial and algae inhibition performance by coral sand-supported nano-Ag composites DOI
Sufeng Wang,

Fengjing Lv,

Wen Zhang

et al.

Environmental Science Nano, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 1, 2025

Coral sand (CS) was utilized as a substrate to immobilize nano silver, resulting in the new composite material CS-Ag. CS-Ag could achieve continuous sterilization and algae inhibition.

Language: Английский

Citations

0
In Vivo Study and Cytotoxicity of Migrated Silver Nanoparticles (AgNPs) from Cellulose/LDPE/AgNP Nanocomposite in Highly Perishable Food (Fish Fillet) Packaging DOI
Faegheh Alsadat Mortazavi Moghadam,

Sousan Rasouli,

Faezeh Alsadat Mortazavi Moghadam

et al.

ACS Food Science & Technology, Journal Year: 2025, Volume and Issue: unknown

Published: Feb. 4, 2025

Language: Английский

Citations

0
Defining Acceptance Criteria for Silver Nanoparticles: Correlating Synthesis Quality with Biological Outcomes in an In Vitro Lung Cancer Model DOI Creative Commons
Bárbara Gomes,

Marjorie Dardis Murucci,

Wanderson de Souza

et al.

Nano Trends, Journal Year: 2025, Volume and Issue: 9, P. 100090 - 100090

Published: Feb. 14, 2025

Language: Английский

Citations

0
Polyurethane infused with heparin capped silver nanoparticles dressing for wound healing application: Synthesis, characterization and antimicrobial studies DOI Creative Commons
Jayshree H. Ahire, Qi Wang,

Gary Rowley

et al.

International Journal of Biological Macromolecules, Journal Year: 2024, Volume and Issue: unknown, P. 136557 - 136557

Published: Oct. 1, 2024

Language: Английский

Citations

3
Utilizing Mitracarpus scaber extracts for green synthesis of silver nanoparticles: Exploring physicochemical properties and potential chemopreventive activity against N-methyl-nitrosourea- induced prostate carcinoma in rats DOI

Temitayo Adesipe,

Emeka Iweala, Ismail O. Ishola

et al.

Nano-Structures & Nano-Objects, Journal Year: 2024, Volume and Issue: 40, P. 101363 - 101363

Published: Oct. 1, 2024

Language: Английский

Citations

0