Emerging challenges in antimicrobial resistance: implications for pathogenic microorganisms, novel antibiotics, and their impact on sustainability DOI Creative Commons
Shikha Sharma, Abhishek Chauhan, Anuj Ranjan

et al.

Frontiers in Microbiology, Journal Year: 2024, Volume and Issue: 15

Published: April 29, 2024

Overuse of antibiotics is accelerating the antimicrobial resistance among pathogenic microbes which a growing public health challenge at global level. Higher causes severe infections, high complications, longer stays hospitals and even increased mortality rates. Antimicrobial (AMR) has significant impact on national economies their systems, as it affects productivity patients or caregivers due to prolonged hospital with economic costs. The main factor AMR includes improper excessive use antimicrobials; lack access clean water, sanitation, hygiene for humans animals; poor infection prevention control measures in hospitals; medicines vaccines; awareness knowledge; irregularities legislation. represents problem, epidemiological surveillance systems have been established, aiming promote collaborations directed well-being human animal balance ecosystem. MDR bacteria such E. coli , Staphylococcus aureus Pseudomonas aeruginosa Enterococcus spp., Acinetobacter Klebsiella pneumonia can cause death. These microorganisms variety antibiotic mechanisms, development drug-deactivating targets, alterations decrease intracellular concentration, render themselves resistant numerous antibiotics. In context, United Nations issued Sustainable Development Goals (SDGs) 2015 serve worldwide blueprint better, more equal, sustainable existence our planet. SDGs place context socioeconomic issues; also, continued growth may hinder achievement SDGs. this review, we discuss role environmental pollution rise AMR, different mechanisms underlying resistance, threats posed by microbes, novel antibiotics, strategies One Health combat sustainability goals.

Language: Английский

Antibiotic resistance in the environment DOI Open Access
D. G. Joakim Larsson, Carl‐Fredrik Flach

Nature Reviews Microbiology, Journal Year: 2021, Volume and Issue: 20(5), P. 257 - 269

Published: Nov. 4, 2021

Language: Английский

Citations

1738

Insights into the Fate and Removal of Antibiotics in Engineered Biological Treatment Systems: A Critical Review DOI
Akashdeep Singh Oberoi, Yanyan Jia, Huiqun Zhang

et al.

Environmental Science & Technology, Journal Year: 2019, Volume and Issue: 53(13), P. 7234 - 7264

Published: June 3, 2019

Antibiotics, the most frequently prescribed drugs of modern medicine, are extensively used for both human and veterinary applications. Antibiotics from different wastewater sources (e.g., municipal, hospitals, animal production, pharmaceutical industries) ultimately discharged into treatment plants. Sorption biodegradation two major removal pathways antibiotics during biological processes. This review provides fundamental insights sorption mechanisms classes with diverse physical–chemical attributes. Important factors affecting behavior also highlighted. Furthermore, this sheds light on critical role extracellular polymeric substances adsorption their in engineered systems. Despite advancements, systems only moderately effective (48–77%) antibiotics. In review, we systematically summarize various discussion efficiency, mechanisms, bioreactor operating conditions removal, recent innovative advancements. Besides, relevant background information including classification, properties, occurrence environment is briefly covered. aims to advance our understanding fate outlines future research directions.

Language: Английский

Citations

823

Occurrence and fate of antibiotics, antibiotic resistant genes (ARGs) and antibiotic resistant bacteria (ARB) in municipal wastewater treatment plant: An overview DOI
Jianlong Wang,

Libing Chu,

László Wojnárovits

et al.

The Science of The Total Environment, Journal Year: 2020, Volume and Issue: 744, P. 140997 - 140997

Published: July 18, 2020

Language: Английский

Citations

710

Antibiotic resistance in European wastewater treatment plants mirrors the pattern of clinical antibiotic resistance prevalence DOI Creative Commons
Katariina Pärnänen, Carlos Narciso‐da‐Rocha, David Kneis

et al.

Science Advances, Journal Year: 2019, Volume and Issue: 5(3)

Published: March 1, 2019

The antibiotic resistome in European UWTPs mirrors the gradient of north-to-south clinical resistance prevalence.

Language: Английский

Citations

459

Antibiotic resistance in drinking water systems: Occurrence, removal, and human health risks DOI
Edmond Sanganyado, Willis Gwenzi

The Science of The Total Environment, Journal Year: 2019, Volume and Issue: 669, P. 785 - 797

Published: March 12, 2019

Language: Английский

Citations

415

Antibiotic resistance in major rivers in the world: A systematic review on occurrence, emergence, and management strategies DOI
R. P. Singh, Akhand Pratap Singh, Sunil Kumar

et al.

Journal of Cleaner Production, Journal Year: 2019, Volume and Issue: 234, P. 1484 - 1505

Published: June 24, 2019

Language: Английский

Citations

394

Remediation of antibiotic wastewater by coupled photocatalytic and persulfate oxidation system: A critical review DOI
Guanyi Chen, Yang Yu,

Lan Liang

et al.

Journal of Hazardous Materials, Journal Year: 2020, Volume and Issue: 408, P. 124461 - 124461

Published: Nov. 4, 2020

Language: Английский

Citations

384

A review of emerging organic contaminants (EOCs), antibiotic resistant bacteria (ARB), and antibiotic resistance genes (ARGs) in the environment: Increasing removal with wetlands and reducing environmental impacts DOI
Joan Garcı́a, María Jesús García-Galán, John W. Day

et al.

Bioresource Technology, Journal Year: 2020, Volume and Issue: 307, P. 123228 - 123228

Published: March 23, 2020

Language: Английский

Citations

320

The effect of bioelectrochemical systems on antibiotics removal and antibiotic resistance genes: A review DOI
Weifu Yan, Yong Xiao,

Weida Yan

et al.

Chemical Engineering Journal, Journal Year: 2018, Volume and Issue: 358, P. 1421 - 1437

Published: Oct. 15, 2018

Language: Английский

Citations

280

Continuous ozonation of urban wastewater: Removal of antibiotics, antibiotic-resistant Escherichia coli and antibiotic resistance genes and phytotoxicity DOI Creative Commons
Iakovos C. Iakovides,

I. Michael-Kordatou,

Nuno F.F. Moreira

et al.

Water Research, Journal Year: 2019, Volume and Issue: 159, P. 333 - 347

Published: May 9, 2019

This work evaluated the removal of a mixture eight antibiotics (i.e. ampicillin (AMP), azithromycin (AZM), erythromycin (ERY), clarithromycin (CLA), ofloxacin (OFL), sulfamethoxazole (SMX), trimethoprim (TMP) and tetracycline (TC)) from urban wastewater, by ozonation operated in continuous mode at different hydraulic retention times (HRTs) 10, 20, 40 60 min) specific ozone doses 0.125, 0.25, 0.50 0.75 gO3 gDOC- 1). As expected, efficiency was highly dose- contact time-dependent. The parent compounds selected to levels below their detection limits achieved with HRT min dose 0.125 1. effect also investigated microbiological genomic level, studying process respect inactivation Escherichia coli antibiotic-resistant E. coli, as well reduction abundance antibiotic resistance genes (ARGs). total cultivable under experimental conditions 0.25 gDOC-1, which all were already degraded. regrowth examinations revealed that higher concentrations required for permanent Limit Quantification (

Language: Английский

Citations

279