Frontiers in Microbiology,
Journal Year:
2024,
Volume and Issue:
15
Published: April 29, 2024
Overuse
of
antibiotics
is
accelerating
the
antimicrobial
resistance
among
pathogenic
microbes
which
a
growing
public
health
challenge
at
global
level.
Higher
causes
severe
infections,
high
complications,
longer
stays
hospitals
and
even
increased
mortality
rates.
Antimicrobial
(AMR)
has
significant
impact
on
national
economies
their
systems,
as
it
affects
productivity
patients
or
caregivers
due
to
prolonged
hospital
with
economic
costs.
The
main
factor
AMR
includes
improper
excessive
use
antimicrobials;
lack
access
clean
water,
sanitation,
hygiene
for
humans
animals;
poor
infection
prevention
control
measures
in
hospitals;
medicines
vaccines;
awareness
knowledge;
irregularities
legislation.
represents
problem,
epidemiological
surveillance
systems
have
been
established,
aiming
promote
collaborations
directed
well-being
human
animal
balance
ecosystem.
MDR
bacteria
such
E.
coli
,
Staphylococcus
aureus
Pseudomonas
aeruginosa
Enterococcus
spp.,
Acinetobacter
Klebsiella
pneumonia
can
cause
death.
These
microorganisms
variety
antibiotic
mechanisms,
development
drug-deactivating
targets,
alterations
decrease
intracellular
concentration,
render
themselves
resistant
numerous
antibiotics.
In
context,
United
Nations
issued
Sustainable
Development
Goals
(SDGs)
2015
serve
worldwide
blueprint
better,
more
equal,
sustainable
existence
our
planet.
SDGs
place
context
socioeconomic
issues;
also,
continued
growth
may
hinder
achievement
SDGs.
this
review,
we
discuss
role
environmental
pollution
rise
AMR,
different
mechanisms
underlying
resistance,
threats
posed
by
microbes,
novel
antibiotics,
strategies
One
Health
combat
sustainability
goals.
Environmental Science & Technology,
Journal Year:
2019,
Volume and Issue:
53(13), P. 7234 - 7264
Published: June 3, 2019
Antibiotics,
the
most
frequently
prescribed
drugs
of
modern
medicine,
are
extensively
used
for
both
human
and
veterinary
applications.
Antibiotics
from
different
wastewater
sources
(e.g.,
municipal,
hospitals,
animal
production,
pharmaceutical
industries)
ultimately
discharged
into
treatment
plants.
Sorption
biodegradation
two
major
removal
pathways
antibiotics
during
biological
processes.
This
review
provides
fundamental
insights
sorption
mechanisms
classes
with
diverse
physical–chemical
attributes.
Important
factors
affecting
behavior
also
highlighted.
Furthermore,
this
sheds
light
on
critical
role
extracellular
polymeric
substances
adsorption
their
in
engineered
systems.
Despite
advancements,
systems
only
moderately
effective
(48–77%)
antibiotics.
In
review,
we
systematically
summarize
various
discussion
efficiency,
mechanisms,
bioreactor
operating
conditions
removal,
recent
innovative
advancements.
Besides,
relevant
background
information
including
classification,
properties,
occurrence
environment
is
briefly
covered.
aims
to
advance
our
understanding
fate
outlines
future
research
directions.
Water Research,
Journal Year:
2019,
Volume and Issue:
159, P. 333 - 347
Published: May 9, 2019
This
work
evaluated
the
removal
of
a
mixture
eight
antibiotics
(i.e.
ampicillin
(AMP),
azithromycin
(AZM),
erythromycin
(ERY),
clarithromycin
(CLA),
ofloxacin
(OFL),
sulfamethoxazole
(SMX),
trimethoprim
(TMP)
and
tetracycline
(TC))
from
urban
wastewater,
by
ozonation
operated
in
continuous
mode
at
different
hydraulic
retention
times
(HRTs)
10,
20,
40
60
min)
specific
ozone
doses
0.125,
0.25,
0.50
0.75
gO3
gDOC-
1).
As
expected,
efficiency
was
highly
dose-
contact
time-dependent.
The
parent
compounds
selected
to
levels
below
their
detection
limits
achieved
with
HRT
min
dose
0.125
1.
effect
also
investigated
microbiological
genomic
level,
studying
process
respect
inactivation
Escherichia
coli
antibiotic-resistant
E.
coli,
as
well
reduction
abundance
antibiotic
resistance
genes
(ARGs).
total
cultivable
under
experimental
conditions
0.25
gDOC-1,
which
all
were
already
degraded.
regrowth
examinations
revealed
that
higher
concentrations
required
for
permanent
Limit
Quantification
(