Toxics,
Journal Year:
2023,
Volume and Issue:
11(11), P. 903 - 903
Published: Nov. 5, 2023
Environmental
pollution
is
a
growing
threat
to
natural
ecosystems
and
one
of
the
world’s
most
pressing
concerns.
The
increasing
worldwide
use
pharmaceuticals
has
elevated
their
status
as
significant
emerging
contaminants.
Pharmaceuticals
enter
aquatic
environments
through
multiple
pathways
related
anthropogenic
activity.
Their
high
consumption,
insufficient
waste
treatment,
incapacity
organisms
completely
metabolize
them
contribute
accumulation
in
environments,
posing
all
life
forms.
Various
analytical
methods
have
been
used
quantify
pharmaceuticals.
Biotechnology
advancements
based
on
next-generation
sequencing
(NGS)
techniques,
like
eDNA
metabarcoding,
enabled
development
new
for
assessing
monitoring
ecotoxicological
effects
metabarcoding
valuable
biomonitoring
tool
pharmaceutical
because
it
(a)
provides
an
efficient
method
assess
predict
status,
(b)
identifies
sources,
(c)
tracks
changes
levels
over
time,
(d)
assesses
ecological
impact
pollution,
(e)
helps
prioritize
cleanup
mitigation
efforts,
(f)
offers
insights
into
diversity
composition
microbial
other
bioindicator
communities.
This
review
highlights
issue
while
emphasizing
importance
using
modern
NGS-based
actions
its
environmental
more
consistently
effectively.
Results in Engineering,
Journal Year:
2022,
Volume and Issue:
16, P. 100671 - 100671
Published: Sept. 28, 2022
Hospitals
played
vital
role
in
the
maintenance
and
sustenance
of
human
health.
However,
hospital
activities
generate
high
volume
toxic
solid
liquid
containing
diverse
inorganic,
organic
microbial
wastes
released
untreated
into
ecosystem.
The
management
wastewater
particular
has
been
a
major
source
concern
due
to
presence
unregulated
emerging
micro-pollutants
at
concentrations
range
ng/L
μg/L.
These
pollutants
low
concentration
exert
different
potential
health
effects
on
aquatic
species.
In
this
review,
formation,
composition,
properties
ecotoxicology
selected
(Norfloxacin,
Ofloxacin,
Ciprofloxacin,
Clofibric
acid
Carbamazepine)
were
reviewed.
review
also
elucidates
detection
quantification
micropollutants
by
Spectrophotometry
techniques,
Gas
Chromatography,
Ion
Chromatography-Mass
spectrometry,
High-Performance
Liquid
Chromatography.
Furthermore,
treatment
through
physical,
biological,
chemical,
adsorption
advanced
oxidation
processes
such
as
photocatalysis
photo-Fenton
including
their
operational
mechanism
provided.
chemistry
degradation
several
intermediates
It
was
found
that
conventional
methods
are
not
designed
for
effective
removal
these
because
they
exist
mixtures
very
exerts
toxicological
effects.
reveals
no
single
technology
can
effectively
detoxify
wastewater,
instead
combination
(phototcatalytic/adsorption
or
photo-fenton/adsorption)
most
appropriate
treatment.
Finally,
regular
monitoring
determination
physicochemical
ecotoxicological
parameters
recommended.
Environment International,
Journal Year:
2023,
Volume and Issue:
175, P. 107928 - 107928
Published: April 11, 2023
Pharmaceutical
residues
are
the
undecomposed
remains
from
drugs
used
in
medical
and
food
industries.
Due
to
their
potential
adverse
effects
on
human
health
natural
ecosystems,
they
of
increasing
worldwide
concern.
The
acute
detection
pharmaceutical
can
give
a
rapid
examination
quantity
then
prevent
them
further
contamination.
Herein,
this
study
summarizes
discusses
most
recent
porous
covalent-organic
frameworks
(COFs)
metal–organic
(MOFs)
for
electrochemical
various
residues.
review
first
introduces
brief
overview
drug
toxicity
its
living
organisms.
Subsequently,
different
materials
techniques
discussed
with
materials'
properties
applications.
Then
development
COFs
MOFs
has
been
addressed
structural
sensing
Further,
stability,
reusability,
sustainability
MOFs/COFs
reviewed
discussed.
Besides,
MOFs'
limits,
linear
ranges,
role
functionalities,
immobilized
nanoparticles
analyzed
Lastly,
summarized
[email
protected]
composite
as
sensors,
fabrication
strategies
enhance
potential,
current
challenges
area.
Frontiers in Environmental Science,
Journal Year:
2022,
Volume and Issue:
10
Published: Dec. 16, 2022
Pharmaceuticals
are
essential
for
human
health,
but
they
become
an
environmental
concern
when
entering
the
environment
which
occurs
residues
excreted
after
consumption
or
unused
pharmaceuticals
discarded
improperly.
Although
there
no
developed
detection
methods
all
that
reach
ecosystem,
certain
groups
have
been
proven
to
cause
adverse
effects
on
ecosystems,
including
increased
mortality
in
aquatic
species
and
changes
physiology,
behavior,
reproduction.
Particular
attention
is
devoted
these
of
their
impact.
In
this
review,
authors
suggest
measures
reduction
environment,
with
a
strong
emphasis
prevention.
Various
policy
interventions
recommended
across
lifecycle
source-directed,
user-orientated,
waste
management
measures,
prevent
creation
household
pharmaceutical
ensure
environmentally
friendly
ways
disposal.
Preventive
include
rational
consumption,
prescribing
greener
drugs,
designing
benign
easily
biodegradable,
improved
disease
prevention,
personalized
medicine,
enhanced
dimensioning
pack
sizes,
marketplaces
redistribution
pharmaceuticals.
The
next
step
unavoidable
so
proper
collection
disposal
utmost
importance.
Finally,
educating
health
professionals
public
partnership
between
healthcare
scientists
vital
significance
stages
pharmaceuticals’
lifecycle.
Minimalization
level
will
benefit
life.
Arabian Journal of Chemistry,
Journal Year:
2023,
Volume and Issue:
16(5), P. 104699 - 104699
Published: Feb. 23, 2023
Pharmaceuticals
are
a
unique
class
of
emerging
contaminants
owing
to
their
intrinsic
ability
induce
physiological
effects
on
man
and
animals
at
low
concentrations.
released
into
the
environment
via
diverse
routes;
human
animal
wastes
major
sources.
The
persistence
mode
action
pharmaceuticals
in
make
them
concern.
Among
methods
available
for
wastewater
treatment,
adsorption
technique
is
found
be
effective
easy
operate.
expensive
nature
commercial
activated
carbons,
however,
created
limitation
technique;
hence
exploration
low-cost
sustainable
adsorbents
removal
different
categories
water
contaminants.
Agricultural
offer
such
advantages
as
low-cost,
abundance
eco-friendly
materials
adsorbent
preparation.
Herein
presented
category
classes
cum
risks
associated
with
environment.
chemistry
carbon/agro
viz-a-viz
suitability
potency
pharmaceutical
waste
were
reviewed;
benefits
agricultural
usage
have
also
been
presented.
Various
challenges,
gaps
research
prospects
current
field
discussion
herein
This
work
will
serve
tool
public
education
enlightenment,
help
environmentalists
plans
envisaged
threats
guide
policy
makers.
Environmental Engineering Research,
Journal Year:
2024,
Volume and Issue:
29(5), P. 230636 - 0
Published: Feb. 6, 2024
Metal-organic
frameworks
(MOF)
are
a
class
of
porous
hybrid
materials
metal
ions
linked
by
organic
bridging
ligands.
These
consist
different
families
crystalline
with
and
metal-ion
clusters
the
coordination
bonds
suitable
possess
high
surface
area,
variable
pore
sizes,
various
functions,
excellent
thermal
stability.
As
result,
these
unique
tailored
MOF
found
varied
applications
in
electrochemical
sensor
development.
The
review
critically
examines
approach
to
synthesizing
wide
range
compounds.
utilization
fabricating
small-scale
device
demonstrates
ability
detect
water
contaminants
aquatic
environments.
Moreover,
it
showcased
an
in-depth
advancement
development
utilizing
MOFs
materials.
efficient
use
sensors
is
discussed
presents
studies’
challenges
future
perspectives.
Toxics,
Journal Year:
2022,
Volume and Issue:
10(2), P. 81 - 81
Published: Feb. 9, 2022
Pharmaceuticals
are
actually
identified
as
a
threat
to
the
ecosystem.
Nowadays,
growing
consumption
of
antineoplastic
agents
has
been
related
their
continuous
input
in
natural
environments.
These
substances
can
interfere
with
physiological
and
biochemical
processes
aquatic
species
over
entire
life
cycle.
Oxaliplatin
(OXA)
is
widely
used
chemotherapeutic
agent
treat
colon
or
rectal
cancer.
This
study
was
aimed
evaluate
developmental
toxicity
OXA
exposure.
To
this
end,
zebrafish
embryos
were
incubated
0.001,
0.1,
0.5
mg/L
OXA.
At
different
timepoints
mortality
rate,
hatching
abnormalities,
histological
analysis,
oxidative
stress
mRNA
expression
gene
evaluated.
Our
results
showed
that
exposure
induce
increased
abnormalities
reducing
rate.
Histological
analysis
demonstrated
induced
liver,
intestine,
muscle
heart
injury.
Superoxide
dismutase
catalase
activities
significantly
after
demonstrating
its
effects.
The
levels
apoptosis-related
genes
(caspase-3,
bax
bcl-2)
upregulated
by
In
conclusion,
we
highlighted
led
dose-related
toxicity,
apoptosis.
