Multi-and transgenerational synergistic effects of glyphosate and chlorpyrifos at environmentally relevant concentrations in the estuarine rotifer Proales similis DOI
Uriel Arreguin Rebolledo, Federico Páez‐Osuna, Miguel Betancourt‐Lozano

et al.

Environmental Pollution, Journal Year: 2022, Volume and Issue: 318, P. 120708 - 120708

Published: Nov. 18, 2022

Language: Английский

Perfluorinated Iodine Alkanes Promoted Neural Differentiation of mESCs by Targeting miRNA-34a-5p in Notch-Hes Signaling DOI
Zhihua Ren, Tingting Ku,

Yurou Gao

et al.

Environmental Science & Technology, Journal Year: 2022, Volume and Issue: 56(12), P. 8496 - 8506

Published: May 24, 2022

The neurodevelopmental process is highly vulnerable to environmental stress from exposure endocrine-disrupting chemicals. Perfluorinated iodine alkanes (PFIs) possess estrogenic activities, while their potential toxicity remains blurry. In the present study, effects of two PFIs, including dodecafluoro-1,6-diiodohexane (PFHxDI) and tridecafluorohexyl iodide (PFHxI), were investigated in neural differentiation mouse embryonic stem cells (mESCs). Without influencing cytobiological mESCs, PFIs interfered triploblastic development by increasing ectodermal differentiation, thus promoting subsequent neurogenesis. temporal regulation Notch-Hes signaling through targeting mmu-miRNA-34a-5p provided a substantial explanation for underlying mechanism PFI-promoted mESC commitment lineage. findings herein new knowledge on toxicities which would help advance health risk assessment these kinds emerging

Language: Английский

Citations

17
Transgenerational effects of bisphenol A on zebrafish reproductive tissues and sperm motility DOI Creative Commons

Mst. Habiba Mostari,

Md. Mostafizur Rahaman,

Mst. Afroza Akhter

et al.

Reproductive Toxicology, Journal Year: 2022, Volume and Issue: 109, P. 31 - 38

Published: March 2, 2022

Language: Английский

Citations

16
Transcriptomic profiling reveals the neuroendocrine-disrupting effect and toxicity mechanism of TBBPA-DHEE exposure in zebrafish (Danio rerio) during sexual development DOI
Emmanuel Sunday Okeke, Weiwei Feng,

Chang Song

et al.

The Science of The Total Environment, Journal Year: 2022, Volume and Issue: 858, P. 160089 - 160089

Published: Nov. 9, 2022

Language: Английский

Citations

16
Multigenerational impacts of EE2 on reproductive fitness and immune competence of marine medaka DOI
Drew R. Peterson, Frauke Seemann, Teng Wan

et al.

Aquatic Toxicology, Journal Year: 2023, Volume and Issue: 260, P. 106584 - 106584

Published: May 20, 2023

Language: Английский

Citations

8
Multi-and transgenerational synergistic effects of glyphosate and chlorpyrifos at environmentally relevant concentrations in the estuarine rotifer Proales similis DOI
Uriel Arreguin Rebolledo, Federico Páez‐Osuna, Miguel Betancourt‐Lozano

et al.

Environmental Pollution, Journal Year: 2022, Volume and Issue: 318, P. 120708 - 120708

Published: Nov. 18, 2022

Language: Английский

Citations

13