Agro-waste derived rGO/CaCO3 hybrid nanostructure as green adsorbent for waste water treatment

Journal of the Taiwan Institute of Chemical Engineers, Journal Year: 2025, Volume and Issue: unknown, P. 105925 - 105925

Published: Jan. 1, 2025

Language: Английский

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Mechanistic insights and emerging therapeutic stratagems for Alzheimer’s disease

Ageing Research Reviews, Journal Year: 2024, Volume and Issue: 97, P. 102309 - 102309

Published: April 13, 2024

Language: Английский

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Marine polysaccharides, proteins, lipids, and silica for drug delivery systems: A review

International Journal of Biological Macromolecules, Journal Year: 2023, Volume and Issue: 253, P. 127145 - 127145

Published: Sept. 29, 2023

Language: Английский

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Folic acid receptor conjugated mesoporous CaCO3 nanoformulation for the therapeutic potential against lung carcinoma

Journal of Drug Delivery Science and Technology, Journal Year: 2024, Volume and Issue: 92, P. 105392 - 105392

Published: Jan. 19, 2024

Language: Английский

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Organic fertilizer integrated with marine waste derived CaCO3 nanocarrier system: A focus on enhanced yield and quality in tomato cultivation

Scientific Reports, Journal Year: 2024, Volume and Issue: 14(1)

Published: Oct. 25, 2024

Language: Английский

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Fabrication of a natural nanocomposite from Syzygium cumini and squid bone waste decorated with Cu-Nps for simultaneous use in the triple method of photodynamic/photothermal/chemotherapy

Biomedical Materials, Journal Year: 2024, Volume and Issue: 20(1), P. 015004 - 015004

Published: Nov. 8, 2024

This work reports a new nano platform made from natural materials for phototherapy (PT) applications. For this purpose, calcium carbonate nanoparticles (NPs) derived Persian Gulf squid bones as drug carrier, Syzygium cumini (dye extracted the fruit of trees) photosensitizer, and Doxorubicin chemotherapy (CHT) have been used. In addition, copper NPs were added to above nanocomposition increase efficiency photothermal (PTT) treatment. PT, samples irradiated by an 808 nm laser (1 W cm

Language: Английский

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Chuanxiong Rhizoma regulates ferroptosis and the immune microenvironment in ischemic stroke through the JAK-STAT3 pathway

Scientific Reports, Journal Year: 2024, Volume and Issue: 14(1)

Published: Dec. 28, 2024

Ferroptosis is linked to various pathological conditions; however, the specific targets and mechanisms through which traditional Chinese medicine influences ischemic stroke (IS)-induced ferroptosis remain poorly understood. In this study, data from Gene Expression Omnibus disease target databases (OMIM, GeneCards, DisGeNet, TTD, DrugBank) were integrated with ferroptosis-related gene datasets. To identify key molecular of Chuanxiong Rhizoma (CX), drug ingredient databases, including PubChem TCMBank, employed map CX-related (CX-DEGs-FRG CX-IS-FRG). relevant signaling pathways analyzed using weighted co-expression network analysis, protein-protein interaction networks, Ontology, Kyoto Encyclopedia Genes Genomes pathway enrichment. The least absolute shrinkage selection operator regression support vector machine methods utilized intersecting genes, predictive accuracy core was evaluated receiver operating characteristic curve analysis. Immune cell infiltration in IS microenvironment assessed CIBERSORT, followed by docking CX's active components targets. JAK-STAT3 identified as a critical regulatory mechanism, five (ALOX5, PTGS2, STAT3, G6PD, HIF1A) emerged central IS-induced ferroptosis. Elevated CD8 + T cells neutrophils significantly correlated IS. Notably, mandenol myricanone demonstrated strong binding affinities these targets, validated results network-based conclusion, pathway, its regulation ALOX5, HIF1A, could play crucial role modulating immune responses These findings suggest that CX serve potential therapeutic approach for IS, targeting microenvironment.

Language: Английский

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Integrative organic fertilizer immobilized in marine waste derived CaCO3 nanocarrier system towards quality and quantity enhancement of tomato cultivation

Research Square (Research Square), Journal Year: 2023, Volume and Issue: unknown

Published: Nov. 30, 2023

Abstract Tomatoes are rich the lycopene, β-carotene, ascorbic acid and other mineral sources including phosphorus, potassium, zinc, magnesium iron. Major constraints in tomato cultivation were high cost, poor due to adverse weather conditions, pest attacks, microbial infections nutritional deficiency complications. Conventional fertilizers pesticides, fungicides growth regulators effective at higher concentration, which induces specific toxic effects on soil fertility, plant yield also affects health status of humans, animals associated microbes. The use organic meet nutrient demand increases acidity affecting turned focus researchers towards nanofertilizer. present study focuses synthesis marine waste derived CaCO 3 nanoparticles formulated with azadirachtin panchakavya emulsion develop a nanofertilizer characterized by UV-Visible, FTIR, DLS, EDX, ICP-OES spectra along FE-SEM, HR-TEM, TGA BET analysis. effectively inhibited fusarium wilt causing fungal pathogen exhibited enhanced tomatoes against attack effect foliar treatment. Overall, fabricated exhibits synergistic role fertilizer, pesticide, fungicide regulator cultivation.

Language: Английский

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Integrating Ayurvedic philosophy with modern technologies for drug research and development: A critical need of mechanistic insights for wider acceptability

Journal of Ayurveda and Integrative Medicine, Journal Year: 2024, Volume and Issue: 15(5), P. 100954 - 100954

Published: Sept. 1, 2024

Language: Английский

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Dual Functionality of hydroxyapatite nanocarriers in neurodegenerative biomarker management as immunosensor and neuroprotective therapeutic system

Microchemical Journal, Journal Year: 2024, Volume and Issue: unknown, P. 112358 - 112358

Published: Dec. 1, 2024

Language: Английский

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