The
“ethylenediamine
tetraacetic
acid
disodium
salt-metal”
(“EDTA•2Na-Mn+”)
based-signal
regulation
strategy
has
been
successfully
developed
for
the
construction
of
vigorous
and
progressive
immunoassayswith
various
signals,
including
1)
EDTA•2Na-Fe3+@aptamer/gold
nanorods
(Ea-Fe3+/AuNRs)
with
photothermal
signal;
2)
silica
nanoparticles
(SiO2
NPs)
@EDTA•2Na-Au3+@aptamer/gold
(Sea-Au3+/AuNPs)
colorimetric
3)
SiO2
NPs@EDTA•2Na-Cd2+@aptamer/cDNA/gold
nanoclusters
(Seac-Cd2+/AuNCs)
fluorescence
signal.
Concretely,
EDTA•2Na
chelates
Fe3+,
Au3+,
Cd2+
fiercely
to
selectively
regulate
metallization
AuNRs,
growth
AuNPs,
synthesis
AuNCs.Using
Aflatoxin
B1
as
a
model
target,
these
assays
could
achieve
limits
detection
at
0.15
pg/mL,
0.19
0.2
fg/mL,
respectively.
relative
standard
deviation
2.17
%
indicates
good
consistency
food
samples
detection.
Compared
conventional
ELISA,
high-performance
enzyme-free
“EDTA•2Na-Mn+”
platforms
exhibit
superiors
low
cost
enhanced
sensitivity,
thereby
expanding
building
biosensors
that
eliminate
use
enzymes.
Importantly,
endow
multiple
signals
can
realize
mutually
corroborate
noninterference
one
target
diversity
endows
flexible
selection
those
different
color
matrix.
Frontiers in Plant Science,
Journal Year:
2024,
Volume and Issue:
15
Published: Nov. 13, 2024
With
the
growth
of
global
population
and
increasing
scarcity
resources,
sustainability
efficiency
improvement
agricultural
production
have
become
urgent
needs.
The
rapid
development
nanotechnology
provides
new
solutions
to
this
challenge,
especially
application
nanoparticles
in
agriculture,
which
is
gradually
demonstrating
its
unique
advantages
broad
prospects.
Nonetheless,
various
can
influence
plant
diverse
manners,
often
through
distinct
mechanisms
action.
Beyond
their
direct
effects
on
itself,
they
frequently
alter
physicochemical
properties
soil
modulate
structure
microbial
communities
rhizosphere.
This
review
focuses
intently
methods
growth,
delving
deeply
into
interactions
between
plants,
as
well
with
communities.
aim
offer
a
comprehensive
reference
for
utilization
functionalized
sector.
ACS Omega,
Journal Year:
2025,
Volume and Issue:
unknown
Published: Jan. 12, 2025
A
sensitive
electrochemical
immunosensor
for
procymidone
detection
was
developed
based
on
a
supramolecular
amplification
strategy.
β-Cyclodextrin
(β-CD)-based
nanomaterials
were
employed
to
immobilize
ferrocene
derivative
(FC)-functionalized
antibodies/antigens
through
host-guest
interactions.
With
the
presence
of
procymidone,
formed
β-CD-labeled
bioconjugates
immobilized
antibody-modified
electrode
after
immunoreaction,
indicating
fabrication
immunosensor.
The
FC/β-CD
complexes
with
multiplex
electroactive
species
and
provided
more
sites
recognition
groups,
resulting
in
signal
sensor.
Monitored
differential
pulse
voltammetry,
proposed
exhibited
wide
linear
range
from
5
pM
0.1
μM
low
limit
(LOD)
1.67
pM.
as-prepared
possessed
high
sensitivity,
specificity,
stability
showed
great
potential
monitoring
field
food
safety.
Reviews in Aquaculture,
Journal Year:
2025,
Volume and Issue:
17(3)
Published: April 2, 2025
ABSTRACT
Shrimp
is
a
commercially
important
species
in
several
regions
and
among
the
key
global
aquaculture
commodities
essential
for
food
production
security.
Similar
to
most
shrimp‐producing
countries,
shrimp
Malaysia
suffers
from
recurring
disease
outbreaks
that
consequently
impact
overall
economy.
The
use
of
antimicrobial
agents,
particularly
antibiotics,
prophylactic
treatment
growth
enhancement
has
increased
spread
antimicrobial‐resistant
bacteria
aquatic
environment.
development
dissemination
other
potential
sources
contamination
waterways
are
facilitated
by
continuous
application
antibiotics
farming,
municipalities,
livestock,
hospitals
pharmaceutical
sources.
This
situation
contributes
resistance
(AMR)
phenomenon,
One
Health
issue
with
detrimental
effects
on
human
animal
health
as
well
Addressing
risks
associated
AMR
remains
highly
challenging
due
intensification
farming
trends,
which
heightens
outbreaks,
limited
availability
alternatives
many
farmers
seeking
prevent
crop
failure.
In
this
review,
we
critically
examine
issues
related
explore
emerging
strategies.
Our
analysis
encompasses
comprehensive
review
existing
literature
Malaysia,
alternative
mitigation
strategies
aimed
at
fostering
more
sustainable
resilient
practices.
Life,
Journal Year:
2023,
Volume and Issue:
13(10), P. 2099 - 2099
Published: Oct. 22, 2023
Candida
is
the
largest
genus
of
medically
significant
fungi.
Although
most
its
members
are
commensals,
residing
harmlessly
in
human
bodies,
some
opportunistic
and
dangerously
invasive.
These
have
ability
to
cause
severe
nosocomial
candidiasis
candidemia
that
affect
viscera
bloodstream.
A
prompt
diagnosis
will
lead
a
successful
treatment
modality.
The
smart
solution
biosensing
technologies
for
rapid
precise
detection
species
has
made
remarkable
progress.
development
point-of-care
(POC)
biosensor
devices
involves
sensor
precision
down
pico-/femtogram
level,
cost-effectiveness,
portability,
rapidity,
user-friendliness.
However,
futuristic
diagnostics
depend
on
exploiting
such
as
multiplexing
high-throughput
screening,
CRISPR,
artificial
intelligence
(AI),
neural
networks,
Internet
Things
(IoT),
cloud
computing
medical
databases.
This
review
gives
an
insight
into
different
designed
species,
especially
albicans
C.
auris,
their
applications
setting.
Chemosensors,
Journal Year:
2024,
Volume and Issue:
12(4), P. 59 - 59
Published: April 9, 2024
With
the
advancement
of
technology
and
increasing
industrial
activity,
anthropogenic
contaminants
are
currently
detected
where
there
is
no
record
their
presence
or
insufficient
information
about
toxicological
impact.
Consequently,
not
sufficiently
robust
local
global
regulations,
ecotoxicological
human
health
risks
critical,
they
may
be
routinely
monitored
despite
being
ubiquitous.
The
interest
in
studying
environmental
contaminants,
including
micropollutants
emerging
complex
water
samples
has
grown
last
decade.
Due
to
concentrations
which
typically
found
environment
rapid
dispersion,
detection
procedures
for
these
substances
must
capable
measuring
very
low
concentrations.
Many
efforts
have
been
made
improve
remediation
develop
novel
analytical
methods
determination.
Although
several
reliable
standard
techniques
monitoring,
pollutant
contamination
requires
simple
inexpensive
massive,
situ
monitoring
campaigns.
In
this
regard,
biosensors
emerged
as
devices
with
high
selectivity,
sensitivity,
easy
operation,
short
analysis
times.
Aptasensors
based
on
a
nucleic
acid
recognition
element
(aptamer).
synthetic
nature,
stability,
production,
aptamers
frequently
employed
bioassays.
This
work
presents
systematic
review
trends
using
aptasensors
detecting
present
samples,
well
estimation
potential
technological
contribution
might
give
monitoring.
Sensors,
Journal Year:
2024,
Volume and Issue:
24(23), P. 7432 - 7432
Published: Nov. 21, 2024
Chronic
and
non-communicable
diseases
(NCDs)
account
for
a
large
proportion
of
global
disorders
mortality,
posing
significant
burdens
on
healthcare
systems.
Early
diagnosis
timely
interference
are
critical
effective
management
disease
prevention.
However,
the
traditional
methods
still
suffer
from
high
costs,
time
delays
in
processing,
infrastructure
requirements
that
usually
unaffordable
resource-constrained
settings.
Aptamer-based
biosensors
have
emerged
as
promising
alternatives
to
offer
enhanced
specificity,
stability,
cost-effectiveness
biomarker
detection.
The
SELEX
(Systematic
Evolution
Ligands
by
Exponential
Enrichment)
methodology
allows
developing
aptamers
with
high-affinity
binding
capabilities
variety
targets,
instance
proteins,
cells,
or
even
small
molecules,
hence
rendering
them
suitable
NCD
diagnosis.
Aptasensors-recent
developments
electrochemical
optical
dominion-offer
much
sensitivity,
selectivity,
stability
detection
across
diverse
range
lung
cancer
leukemia
diabetes
chronic
respiratory
disorders.
This
study
provides
comprehensive
review
progress
aptamer-based
sensors,
focusing
their
role
point-of-care
diagnostics
adaptability
real-world
environment
future
directions
overcoming
current
limitations.
