Food Innovation and Advances,
Journal Year:
2023,
Volume and Issue:
2(1), P. 44 - 59
Published: Jan. 1, 2023
COVID-19,
caused
by
severe
acute
respiratory
syndrome
coronavirus
2
(SARS-CoV-2),
is
a
major
public
health
threat.
Edible
plants
are
rich
in
bioactive
components,
with
variety
of
functions,
such
as
enhancing
immunity,
antiviral,
anti-inflammatory
and
so
on.
Thus,
the
intake
edible
to
boost
body's
resistance
COVID-19
promising
possibly
affordable
strategy.
This
review
revisits
effects
functional
components
from
(such
polyphenols,
polysaccharides,
lectin,
alkaloids,
polyunsaturated
fatty
acids,
terpenoids,
saponins)
on
COVID-19.
The
inhibitory
virus's
entrance
replication,
immune
enhancement
discussed.
And
finally,
we
present
prospects
using
plant
ingredients
vaccine
adjuvants
problems
use
for
prevention
Functional
interacted
structural
proteins
SARS-CoV-2
virus
key
enzymes
recognition
thereby
inhibiting
entry
replication
host.
Meanwhile,
these
had
could
inhibit
cytokine
storms.
Therefore,
believe
that
can
enhance
human
be
applied
development
new
therapies.
Polymers,
Journal Year:
2022,
Volume and Issue:
14(5), P. 983 - 983
Published: Feb. 28, 2022
Biopolymers
are
a
leading
class
of
functional
material
suitable
for
high-value
applications
and
great
interest
to
researchers
professionals
across
various
disciplines.
Interdisciplinary
research
is
important
understand
the
basic
applied
aspects
biopolymers
address
several
complex
problems
associated
with
good
health
well-being.
To
reduce
environmental
impact
dependence
on
fossil
fuels,
lot
effort
has
gone
into
replacing
synthetic
polymers
biodegradable
materials,
especially
those
derived
from
natural
resources.
In
this
regard,
many
types
or
have
been
developed
meet
needs
ever-expanding
applications.
These
currently
used
in
food
expanding
their
use
pharmaceutical
medical
industries
due
unique
properties.
This
review
focuses
uses
industry
provides
future
outlook
biopolymer
industry.
The Science of The Total Environment,
Journal Year:
2021,
Volume and Issue:
801, P. 149719 - 149719
Published: Aug. 19, 2021
Fruits,
vegetables,
spices,
and
herbs
are
a
potential
source
of
phenolic
acids
polyphenols.
These
compounds
known
as
natural
by-products
or
secondary
metabolites
plants,
which
present
in
the
daily
diet
provide
important
benefits
to
human
body
such
antioxidant,
anti-inflammatory,
anticancer,
anti-allergic,
antihypertensive
antiviral
properties,
among
others.
Plentiful
evidence
has
been
provided
on
great
polyphenols
against
different
viruses
that
cause
widespread
health
problems.
As
result,
this
review
focuses
properties
some
their
action
mechanism
various
types
coronaviruses,
influenza,
herpes
simplex,
dengue
fever,
rotavirus,
Also,
it
is
highlight
relationship
between
antioxidant
activities
can
contribute
protection
cells
tissues
body.
The
wide
variety
mechanisms
agents,
polyphenols,
viral
infections
could
be
applied
treatment
prevention
strategy;
but
at
same
time,
used
produce
drugs.
A
recent
example
an
polyphenol
application
deals
with
use
hesperidin
extracted
from
Citrus
sinensis.
relies
its
binding
key
entry
spike
protein
SARS-CoV-2.
Finally,
extraction,
purification
recovery
activity,
essential
for
virus
replication
infection
without
side-effects,
have
critically
reviewed.
Plants,
Journal Year:
2023,
Volume and Issue:
12(6), P. 1217 - 1217
Published: March 7, 2023
Polyphenol
has
been
used
in
treatment
for
some
health
disorders
due
to
their
diverse
promoting
properties.
These
compounds
can
reduce
the
impacts
of
oxidation
on
human
body,
prevent
organs
and
cell
structure
against
deterioration
protect
functional
integrity.
The
abilities
are
attributed
high
bioactivity
imparting
them
antioxidative,
antihypertensive,
immunomodulatory,
antimicrobial,
antiviral
activity,
as
well
anticancer
application
polyphenols
such
flavonoids,
catechin,
tannins,
phenolic
acids
food
industry
bio-preservative
substances
foods
beverages
exert
a
superb
activity
inhibition
oxidative
stress
via
different
types
mechanisms.
In
this
review,
detailed
classification
polyphenolic
compunds
important
with
special
focus
addressed.
Additionally,
ability
inhibit
SARS-CoV-2
could
be
alternative
therapy
treat
COVID
patients.
Inclusions
various
have
demonstrated
extend
shelf
life
they
positive
(antioxidative,
anticancer).
virus
reported.
Considering
natural
occurrence
GRAS
status
highly
recommended
food.
Foods,
Journal Year:
2021,
Volume and Issue:
10(11), P. 2595 - 2595
Published: Oct. 27, 2021
The
importance
of
polyphenols
in
human
health
is
well
known;
these
compounds
are
common
foods,
such
as
fruits,
vegetables,
spices,
extra
virgin
olive
oil
and
wine.
On
the
other
hand,
different
factors
that
modulate
biological
activity
less
known.
Conceptualization
work:
In
this
review
we
took
into
account
about
200
relevant
recent
papers
on
following
topics:
"polyphenols
bioavailability",
matrix
effect",
"food
"polyphenols-cytochromes
interaction",
after
having
reviewed
updated
information
chemical
classification
main
properties
polyphenols,
antioxidant,
anti-radical
anti-inflammatory
activity,
together
with
tricky
link
between
vitro
tests
clinical
trials.
Pharmaceuticals,
Journal Year:
2022,
Volume and Issue:
15(9), P. 1049 - 1049
Published: Aug. 25, 2022
The
COVID-19
outbreak
seems
to
be
the
most
dangerous
challenge
of
third
millennium
due
its
highly
contagious
nature.
Amongst
natural
molecules
for
treatment,
flavonoid
molecule
quercetin
(QR)
is
currently
considered
one
promising.
QR
an
active
agent
against
SARS
and
MERS
antimicrobial,
antiviral,
anti-inflammatory,
antioxidant,
some
other
beneficial
effects.
may
hold
therapeutic
potential
SARS-CoV-2
inhibitory
effects
on
several
stages
viral
life
cycle.
In
fact,
inhibits
entry,
absorption,
penetration
in
SARS-CoV
virus,
which
might
at
least
partly
explained
by
ability
derivatives
inhibit
3-chymotrypsin-like
protease
(3CLpro)
papain-like
(PLpro).
a
potent
immunomodulatory
direct
modulatory
immune
cells,
cytokines,
molecules.
QR-based
nanopreparations
possess
enhanced
bioavailability
solubility
water.
this
review,
we
discuss
prospects
application
as
preventive
treatment
COVID-19.
Given
multifactorial
action
QR,
it
can
very
valid
drug
preventative,
mitigating,
infection,
especially
synergism
with
zinc,
vitamins
C,
D,
E,
polyphenols.
Food Chemistry,
Journal Year:
2021,
Volume and Issue:
373, P. 131594 - 131594
Published: Nov. 14, 2021
The
abundance
of
polyphenols
in
edible
plants
makes
them
an
important
component
human
nutrition.
Considering
the
ongoing
COVID-19
pandemic,
a
number
studies
have
investigated
as
bioactive
constituents.
We
applied
in-silico
molecular
docking
well
dynamics
supported
by
in-vitro
assays
to
determine
inhibitory
potential
various
plant
against
SARS-CoV-2
therapeutic
target,
protease
3CLpro.
Of
initial
screening,
quercetin,
ellagic
acid,
curcumin,
epigallocatechin
gallate
and
resveratrol
showed
IC50
values
11.8
µM
23.4
µM.
In-silico
simulations
indicated
stable
interactions
with
3CLpro
active
site
over
100
ns
production
runs.
Moreover,
surface
plasmon
resonance
spectroscopy
was
used
measure
binding
real
time.
Therefore,
we
provide
evidence
for
inhibition
natural
polyphenols,
suggest
further
research
into
development
these
novel
inhibitors
or
biochemical
probes.
Foods,
Journal Year:
2021,
Volume and Issue:
10(10), P. 2277 - 2277
Published: Sept. 26, 2021
Polyphenols
are
active
substances
against
various
types
of
viral
infections.
Researchers
have
characterized
methods
how
to
isolate
polyphenols
without
losing
their
potential
formulate
pharmaceutical
products.
also
described
mechanisms
common
infections
(i.e.,
influenza,
herpes,
hepatitis,
rotavirus,
coronavirus).
Particular
compounds
been
discussed
together
with
the
plants
in
biomass
which
they
occur.
Quercetin,
gallic
acid
and
epigallocatechin
exemplary
that
inhibit
growth
cycle
viruses.
Special
attention
has
paid
identify
can
be
efficient
coronavirus
It
proven
present
diet
pharmaceuticals
protect
us
from
and,
case
infection,
support
healing
process
by
mechanisms,
i.e.,
block
entry
into
host
cells,
multiplication
virus,
seal
blood
vessels
superinfection.
International Journal of Molecular Sciences,
Journal Year:
2021,
Volume and Issue:
22(20), P. 11069 - 11069
Published: Oct. 14, 2021
The
ongoing
COVID-19
pandemic,
caused
by
the
severe
acute
respiratory
syndrome
coronavirus
2
(SARS-CoV-2)
became
a
globally
leading
public
health
concern
over
past
two
years.
Despite
development
and
administration
of
multiple
vaccines,
mutation
newer
strains
challenges
to
universal
immunity
has
shifted
focus
lack
efficacious
drugs
for
therapeutic
intervention
disease.
As
with
SARS-CoV,
MERS-CoV,
other
non-respiratory
viruses,
flavonoids
present
themselves
as
promising
given
their
success
in
silico,
vitro,
vivo,
more
recently,
clinical
studies.
This
review
focuses
on
data
from
vitro
studies
analyzing
effects
various
key
SARS-CoV-2
targets
presents
an
analysis
structure-activity
relationships
same.
From
27
primary
papers,
69
were
investigated
activities
against
targets,
ranging
3C-like
protease
(3CLpro)
less
explored
nucleocapsid
(N)
protein;
most
quercetin
myricetin
derivatives,
baicalein,
baicalin,
EGCG,
tannic
acid.
We
further
silico
featuring
list
involving
potential
flavonoid-rich
extracts
combination
synthetic
or
polyphenols
suggest
prospects
future
SARS-CoV-2.
