The
enzymatic
modification
of
proteins
using
protein
hydrolase
preparations
to
prepare
bioactive
peptides
has
been
widely
used
in
the
food
industry.
In
this
paper,
dynamic
changes
four
exogenous
enzymes
and
reaction
time
on
process
prepared
sea
cucumber
were
characterized
at
level
macromolecules
peptide
small
molecules
further
reveal
their
effects
reaction.
239
precursor
with
6734
sequences
(3-25
amino
acid
residues)
identified
from
7
group
digestion
products
(Holothuria
leucospilota)
peptidome
analysis.
620
shared
detected
groups
different
hydrolysis
times,
while
177
proteases.
relative
abundance
distribution
non-shared
varied
methods,
revealing
dynamics
HL
proteins.
structural
characteristics
physicochemical
properties
each
differentially
analyzed
combination
bioanalytical
methods.
Monitoring
a
microscopic
perspective
can
help
production
quality
control
functional
cucumbers.
Journal of Agricultural and Food Chemistry,
Journal Year:
2023,
Volume and Issue:
71(44), P. 16435 - 16451
Published: Oct. 26, 2023
Cow's
milk
is
the
most
widely
used
ingredient
in
infant
formulas.
However,
its
specific
protein
composition
can
cause
allergic
reactions.
Finding
alternatives
to
replace
cow's
and
fill
nutritional
gap
with
human
essential
for
health
of
infants.
Proteomic
peptidomic
techniques
have
supported
elucidation
milk's
ingredients.
Recently,
omics
approaches
attracted
increasing
interest
investigation
because
their
high
throughput,
precision,
sensitivity,
reproducibility.
This
review
offers
a
significant
overview
recent
developments
proteomics
peptidomics
study
differences
human,
cow,
donkey
milk.
All
three
types
milks
were
identified
critical
biological
functions
health,
particularly
Donkey
proteins
closer
milk,
less
likely
reactions,
may
be
developed
as
novel
raw
materials
formula
powders.
Foods,
Journal Year:
2025,
Volume and Issue:
14(5), P. 877 - 877
Published: March 4, 2025
The
aim
of
this
study
was
to
identify
and
characterize
the
bioactive
peptide
profile
Podolica
cow's
milk.
This
dairy
product
is
known
for
its
nutritional
properties
related
presence
peculiar
lipids
a
typical
breed
traditionally
reared
in
southern
Italy.
Using
top-down
peptidomics,
we
identified
2213
peptides
milk
samples
from
four
different
farms,
with
19
matching
sequences.
Bioactivities
include
dipeptidyl
peptidase-IV
(DPP-IV)
inhibition,
angiotensin-converting
enzyme
(ACE)
antioxidant
activity,
enhanced
calcium
uptake,
other
potential
antimicrobial
effects.
DPP-IV-inhibitory
(e.g.,
LDQWLCEKL
VGINYWLAHK)
suggest
type
2
diabetes
management,
while
ACE
inhibitors
(such
as
YLGY
FFVAPFPEVFGK)
could
support
cardiovascular
health
by
reducing
hypertension.
Antimicrobial
such
SDIPNPIGSENSEK
VLNENLLR
showed
broad
spectrum
activity
against
various
harmful
microorganisms,
positioning
promising
source
natural
agents.
Additionally,
osteoanabolic,
antianxiety,
immunomodulatory
further
highlight
multifaceted
benefits
associated
Our
findings
underline
functional
richness
bioactivity
properties,
which
enhance
value
derived
products
contribute
sustainable
agricultural
practices.
Future
research
will
explore
these
vivo,
establishing
foundation
foods
supplements
based
on
International Journal of Dairy Technology,
Journal Year:
2024,
Volume and Issue:
77(3), P. 949 - 960
Published: April 1, 2024
The
effect
of
different
thermal
treatments
including
pasteurisation,
ultra‐pasteurisation,
ultra‐high
temperature
instantaneous
sterilisation
and
in‐container
on
physicochemical
properties
peptide
profiles
infant
formula
protein
model
after
in
vitro
digestion
were
investigated.
Results
indicated
that
extent
protein–protein
protein–lactose
interactions
caused
particle
size,
colour,
functional
groups
properties.
Peptide
also
digestion.
About
32,
4,
15,
157
42
unique
peptides,
as
well
14,
10,
12,
13
10
bioactive
peptides
identified
the
five
groups,
respectively.
Pasteurisation
may
be
better
for
processing
formula.
