Possible Mechanisms of Dark Tea in Cancer Prevention and Management: A Comprehensive Review

Nutrients, Journal Year: 2023, Volume and Issue: 15(18), P. 3903 - 3903

Published: Sept. 7, 2023

Tea is one of the most popular drinks in world. Dark tea a kind post-fermented with unique sensory characteristics that produced by special fermentation microorganisms. It contains many bioactive substances, such as polyphenols, theabrownin, polysaccharides, etc., which have been reported to be beneficial human health. This paper reviewed latest research on dark tea’s potential preventing and managing cancer, mechanisms mainly involved anti-oxidation, anti-inflammation, inhibiting cancer cell proliferation, inducing apoptosis, tumor metastasis, regulating intestinal flora. The purpose this review accumulate evidence anti-cancer effects tea, corresponding limitations for prevention management, future prospects, demanding questions about possible contributions an adjuvant.

Language: Английский

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Recent advances in tea seeds (Camellia Sinensis (L.) O. Kuntze): Active ingredients, health effects, and potential applications

Trends in Food Science & Technology, Journal Year: 2023, Volume and Issue: 141, P. 104192 - 104192

Published: Oct. 4, 2023

Language: Английский

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Epigallocatechin-3-gallate mitigates cadmium-induced intestinal damage through modulation of the microbiota-tryptophan-aryl hydrocarbon receptor pathway

Ecotoxicology and Environmental Safety, Journal Year: 2024, Volume and Issue: 280, P. 116520 - 116520

Published: June 3, 2024

Early studies have shown that the gut microbiota is a critical target during cadmium exposure. The prebiotic activity of epigallocatechin-3-gallate (EGCG) plays an essential role in treating intestinal inflammation and damage. However, exact barrier protection mechanism EGCG against exposure remains unclear. In this experiment, four-week-old mice were exposed to (5 mg kg

Language: Английский

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The Aroma Compounds Contributing to the Characteristic Flavour of Ripe Pu-erh Tea and Their Molecular Mechanisms of Interaction with Olfactory Receptors

LWT, Journal Year: 2025, Volume and Issue: unknown, P. 117808 - 117808

Published: April 1, 2025

Language: Английский

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Health-promoting functions and related comprehensive molecular mechanisms of tea: from the perspectives of anti-inflammatory, lipid-lowering, glucose-lowering and anti-cancer effects

Food Bioscience, Journal Year: 2025, Volume and Issue: unknown, P. 106769 - 106769

Published: May 1, 2025

Language: Английский

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Pu-erh tea theabrownin improves the ovarian function and gut microbiota in laying hens

Poultry Science, Journal Year: 2024, Volume and Issue: 103(7), P. 103795 - 103795

Published: April 24, 2024

Studies have reported that theabrownin can moderate the lipid metabolism and intestinal microbiota, thereby affecting health of humans model animals, however research on laying hens is scarce. The present study aimed to investigate effects dietary supplementation metabolism, microbial composition ovarian function in hens. A total 80 (25 wk age) were fed with normal diet (CON) +100 mg/kg (PT group) for 12 wk. results showed addition enhanced villus height duodenum decreased crypt depth jejunum (P < 0.05). At same time, compared CON, concentration IL-6 mRNA expression IL-1β significantly PT group Dietary reduced cholesterol glycerol, while droplet optical density liver Compared CON group, PPARγ, HMG-CoAS, ACC down-regulated CYP8B1 was up-regulated ACE, Chao1 Observed_species indexes cecum microbiota increased by intervention relative abundance Firmicutes (phylum), Lactobacillus (genus) Bacteroidetes ratio, (phylum) organic acids its derivatives serum metabolites resulted higher Bcl-2 SIRT1 ovary estradiol These discovering indicated influenced improving morphology, community structure reducing inflammatory cytokines intestine. hepatic deposition it also cell apoptosis rate improve egg weight which associated pathway.

Language: Английский

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Yellow Teas Protect against DSS-Induced Ulcerative Colitis by Inhibiting TLR4/NF-κB/NLRP3 Inflammasome in Mice

Foods, Journal Year: 2024, Volume and Issue: 13(17), P. 2843 - 2843

Published: Sept. 7, 2024

Yellow tea (YT), a slightly fermented with unique yellowing process and mellow taste, is becoming widely popular. Currently, the YT includes bud yellow (BYT), small-leaf (SYT), large-leaf (LYT) based on maturity of raw materials. Previous studies have shown that has outstanding potential in preventing metabolic syndrome. However, distinct effects mechanisms different types ulcerative colitis (UC) are still unclear. This study investigated continuous or intermittent intervention three water extracts (YTEs) dextran sulfate sodium (DSS)-induced CD-1 mice. The results showed YTE significantly improves syndrome DSS-induced UC Mechanistic reveal YTEs increase expression levels tight junction (TJ) proteins reduce pro-inflammatory cytokines colon by inactivating TLR4/NF-κB/NLRP3. treatment protected intestinal barrier integrity reduced serum lipopolysaccharide (LPS) levels. Interestingly, our indicate better alleviating effect than BYT SYT. before DSS administration certain degree preventive colitis, while after induction significant reversing damage caused DSS. Our indicated drinking may therapeutic UC, especially LYT.

Language: Английский

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Liubao insect tea polyphenols ameliorate DSS-induced experimental colitis by protecting intestinal barrier and regulating intestinal microbiota

Food Chemistry, Journal Year: 2024, Volume and Issue: unknown, P. 142156 - 142156

Published: Nov. 1, 2024

Language: Английский

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Liubao tea extract restrains obesity-related hyperlipidemia via regulation of AMPK/p38/NF-κB pathway and intestinal microbiota

Food Chemistry, Journal Year: 2024, Volume and Issue: 464, P. 141910 - 141910

Published: Nov. 5, 2024

Language: Английский

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Black tea preserves intestinal homeostasis through balancing barriers and microbiota in mice

Frontiers in Nutrition, Journal Year: 2024, Volume and Issue: 11

Published: May 21, 2024

Introduction Black tea, a beverage consumed worldwide, possesses favorable effects on gastrointestinal tract, including nourishing stomach and promoting digestion. Nevertheless, its specific intestinal homeostasis remains inconclusive. Methods We applied black tea to mice prior inducing colitis with DSS then monitored their body weight disease activity index (DAI) daily. When sacrificed, we measured permeability conducted analyses of mucin tight junction proteins. detected inflammatory cytokines, immune cells, related signaling pathways. In addition, the gut microbiota was analyzed through 16S rRNA sequencing, concentrations short-chain fatty acids (SCFAs) were also measured. Results The results showed that tea-treated group significantly rescued DSS-disrupted structure. It reduced relative abundance pathogenic bacterium Turicibacter , while increased beneficial bacteria norank_f_Muribaculaceae restored contents SCFAs such as acetate, propionate, butyrate. protected barrier by reducing levels response-related factors (e.g., TNF-α, IL-6, IL-1β) increasing expression proteins (TJs) ZO-1, occludin). Furthermore, exhibited capacity suppress MMP-9 ICAM-1 well inhibit activation NF-κB pathway. Discussion Our findings provide theoretical framework elucidates mechanisms which preserves homeostasis, highlighting potential preventive strategy against disruptions. This study contributes understanding dietary health.

Language: Английский

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