Molecules,
Journal Year:
2024,
Volume and Issue:
29(24), P. 5893 - 5893
Published: Dec. 13, 2024
Bee
Pollen
(BP)
has
many
advantageous
properties
relying
on
its
multitargeting
potential,
a
new
tendency
in
managing
challenging
illnesses.
In
cancer
and
neurodegeneration,
the
multiple
effects
of
BP
could
be
unequaled
importance
need
further
investigation.
Although
still
limited,
available
data
interestingly
spotlights
some
floral
sources
with
promising
activities
line
this
Adopting
scoping
review
methodology,
we
have
identified
crucial
bioactivities
that
are
widely
recognized
to
individual
compounds
but
remain
completely
untapped
valuable
bee
cocktail.
A
wide
range
these
been
recently
found
endowed
great
potential
modulating
pivotal
processes
neurodegeneration
pathophysiology.
addition,
ubiquitous
only
isolated,
while
number
studied
BPs
remains
extremely
limited
compared
endless
pool
plant
species
worldwide.
We
also
elucidated
clinical
profits
from
perspectives
impeded
by
hurdles
such
as
bioavailability
phytocompounds,
diversity
lack
phytochemical
standardization
BP,
difficulty
selective
targeting
pathophysiological
mechanisms.
finally
present
interesting
insights
guide
future
research
pave
way
for
urgently
needed
simplified
investigations.
Nutrients,
Journal Year:
2023,
Volume and Issue:
15(10), P. 2413 - 2413
Published: May 22, 2023
The
emphasis
on
healthy
nutrition
is
gaining
a
forefront
place
in
current
biomedical
sciences.
Nutritional
deficiencies
and
imbalances
have
been
widely
demonstrated
to
be
involved
the
genesis
development
of
many
world-scale
public
health
burdens,
such
as
metabolic
cardiovascular
diseases.
In
recent
years,
bee
pollen
emerging
scientifically
validated
candidate,
which
can
help
diminish
conditions
through
nutritional
interventions.
This
matrix
being
extensively
studied,
has
proven
very
rich
well-balanced
nutrient
pool.
this
work,
we
reviewed
available
evidence
interest
source.
We
mainly
focused
richness
nutrients
its
possible
roles
main
pathophysiological
processes
that
are
directly
linked
imbalances.
scoping
review
analyzed
scientific
works
published
last
four
focusing
clearest
inferences
perspectives
translate
cumulated
experimental
preclinical
into
clinically
relevant
insights.
promising
uses
for
malnutrition,
digestive
health,
disorders,
other
bioactivities
could
helpful
readjust
homeostasis
(as
it
also
true
case
anti-inflammatory
or
anti-oxidant
needs),
well
benefits
diseases,
were
identified.
knowledge
gaps
identified,
along
with
practical
challenges
hinder
establishment
fructification
these
uses.
A
complete
data
collection
made
major
range
botanical
species
allows
more
robust
clinical
information.
Journal of Functional Biomaterials,
Journal Year:
2023,
Volume and Issue:
14(7), P. 352 - 352
Published: July 4, 2023
The
field
of
biomedical
engineering
highly
demands
technological
improvements
to
allow
the
successful
engraftment
biomaterials
requested
for
healing
damaged
host
tissues,
tissue
regeneration,
and
drug
delivery.
Polymeric
materials,
particularly
natural
polymers,
are
one
primary
suitable
materials
employed
functionalized
enhance
their
biocompatibility
thus
confer
advantageous
features
after
graft
implantation.
Incorporating
bioactive
substances
from
nature
is
a
good
technique
expanding
or
increasing
functionality
biomaterial
scaffolds,
which
may
additionally
encourage
healing.
Our
ecosystem
provides
resources,
like
honeybee
products,
comprising
rich
blend
phytochemicals
with
interesting
properties,
which,
when
functionally
coupled
biomaterials,
result
in
exhibiting
anti-inflammatory,
antimicrobial,
antioxidant
effects.
Bee
pollen
sustainable
product
recently
discovered
as
new
functionalizing
agent
biomaterials.
This
review
aims
articulate
general
idea
using
products
engineering,
mainly
focusing
on
describing
recent
literature
experimental
studies
bee
pollen.
We
have
also
described
underlying
mechanism
attributes
shared
our
perspective
how
future
research
will
benefit
fabrication
such
Frontiers in Nutrition,
Journal Year:
2024,
Volume and Issue:
11
Published: June 4, 2024
Pollen
grains
are
the
male
reproductive
part
of
flowering
plants.
It
is
collected
by
forager
honey
bees
and
mixed
with
their
salivary
secretions,
enzymes,
nectar,
which
form
fermented
pollen
or
“bee
bread”
stored
in
cells
wax
honeycombs.
Bee
(BP)
a
valuable
apitherapeutic
product
considered
nutritional
healthy
food
appreciated
natural
medicine
from
ancient
times.
Recently,
BP
has
been
beneficial
supplement
value-added
that
contains
approximately
250
different
bioactive
components.
numerous
elements
such
as
Mg,
Ca,
Mn,
K,
phenolic
compounds.
possesses
strong
antioxidant,
anti-inflammatory,
antimicrobial,
antiviral,
analgesic,
immunostimulant,
neuroprotective,
anti-cancer,
hepatoprotective
properties.
used
for
purposes
welfare
mankind.
Additionally,
there
growing
interest
bee
products
harvesting
utilizing
many
remedy
nutritive
function.
In
this
review,
impacts
on
organisms
ways
highlighting
its
efficacy
described.
Bioengineering,
Journal Year:
2024,
Volume and Issue:
11(8), P. 829 - 829
Published: Aug. 14, 2024
Bee
products,
abundant
in
bioactive
ingredients,
have
been
utilized
both
traditional
and
contemporary
medicine.
Their
antioxidant,
antimicrobial,
anti-inflammatory
properties
make
them
valuable
for
food,
preservation,
cosmetics
applications.
Honeybees
are
a
vast
reservoir
of
potentially
beneficial
products
such
as
honey,
bee
pollen,
bread,
beeswax,
venom,
royal
jelly.
These
rich
metabolites
vital
to
human
health,
including
proteins,
amino
acids,
peptides,
enzymes,
sugars,
vitamins,
polyphenols,
flavonoids,
minerals.
The
advancement
nanotechnology
has
led
continuous
search
new
natural
sources
that
can
facilitate
the
easy,
low-cost,
eco-friendly
synthesis
nanomaterials.
Nanoparticles
(NPs)
actively
synthesized
using
honeybee
which
serve
dual
purposes
preventive
interceptive
treatment
strategies
due
their
richness
essential
metabolites.
This
review
aims
highlight
potential
role
this
line
applications
catalysts
food
preservatives
point
out
anticancer,
antibacterial,
antifungal,
antioxidant
underlying
impacts.
research
used
several
online
databases,
namely
Google
Scholar,
Science
Direct,
Sci
Finder.
overall
findings
suggest
these
bee-derived
substances
exhibit
remarkable
properties,
making
promising
candidates
economical
production
NPs.
Pharmaceutics,
Journal Year:
2023,
Volume and Issue:
15(7), P. 1797 - 1797
Published: June 23, 2023
Bee
bread
(BB)
is
a
fermented
mixture
of
bee
pollen,
rich
in
proteins,
amino
acids,
fatty
polyphenols,
flavonoids,
as
well
other
bioactive
compounds,
and
considered
functional
food
for
humans.
In
this
study,
we
explored
an
innovative
green
synthesis
colloidal
silver
nanoparticles,
using
BB
extracts
reducing
stabilizing
agents.
A
preliminary
chemical
characterization
the
was
conducted.
The
plasmonic
response
as-synthesized
nanoparticles
(BB-AgNPs)
evaluated
by
UV-Vis
spectroscopy,
while
their
hydrodynamic
diameter
zeta
potential
were
investigated
dynamic
light
spectroscopy
(DLS).
Transmission
electron
microscopy
(TEM)
analysis
pointed
out
polydisperse
NPs
with
quasi-spherical
shapes.
newly
synthesized
showed
good
antioxidant
activity
against
tested
free
radicals,
DPPH,
ABTS•+,
FRAP,
best
results
being
obtained
case
ABTS•+.
BB-AgNPs
exhibited
antibacterial
on
Gram-positive
Gram-negative
bacterial
strains:
herein
S.
aureus,
B.
cereus,
E.
faecalis,
coli,
P.
aeruginosa,
enteritidis,
yeast
C.
albicans,
respectively.
inhibition
diameters
varied
between
7.67
±
0.59
22.21
1.06
mm,
values
minimum
inhibitory
concentration
0.39
6.25
µg/mL.
vitro
antiproliferative
colon
adenocarcinoma,
ATCC
HTB-37
cell
line,
have
shown
that
synthetized
induced
substantial
decrease
tumor
viability
dose-dependent
manner
IC50
ranging
from
24.58
to
67.91
Consequently,
more
investigation
required
comprehend
processes
cytotoxicity
AgNPs
develop
strategies
mitigate
potentially
harmful
effects
harnessing
antimicrobial
properties.