Rice bran ameliorated DSS-induced colitis by suppressing inflammation and modulating gut microbiota DOI Creative Commons

Chenglong Lv,

Xin Li, Xiangfei Li

et al.

Research Square (Research Square), Journal Year: 2024, Volume and Issue: unknown

Published: Oct. 25, 2024

Abstract Globally, the incidence of colitis is on rise. Rice bran (RB) a promising natural dietary supplement. The research aimed to explore how RB impacts in mice caused by dextran sulfate sodium. Notably, administering led better weight control, colon lengths, and decreased disease activity index. Furthermore, it was discovered that boosts antioxidant abilities, elevates short-chain fatty acids concentrations, fortifies intestinal mucosal barrier, lowers histopathology scores, suppresses inflammation. Ileibacterium vane's relative abundance greater mice. Administering reduction comparative vans exhibited an increased Akkermansia muciniphila. These findings provide scientific basis for development as supplement improve gut microbiota dysbiosis enhance comprehensive utilization value RB.

Language: Английский

Incremental extraction of flavonoids from Penthorum chinense Pursh for alleviating dextran sulfate sodium-induced mouse colitis by regulating gut microbiota DOI
Hao Huang, Ye Wang, Yangyang Chen

et al.

Food Bioscience, Journal Year: 2025, Volume and Issue: 64, P. 105897 - 105897

Published: Jan. 10, 2025

Language: Английский

Citations

4
Identification of the key tryptophan metabolic characteristics of Lactiplantibacillus plantarum for aryl hydrocarbon receptor activation and ulcerative colitis alleviation DOI

Xuemei Zuo,

Tingting Zhang, Xueqian Dong

et al.

Food Research International, Journal Year: 2025, Volume and Issue: 203, P. 115766 - 115766

Published: Jan. 23, 2025

Language: Английский

Citations

2
The emerging role of the gut microbiota and its application in inflammatory bowel disease DOI Open Access
Wang Xiu, Jianhua Peng,

Pei-Pei Cai

et al.

Biomedicine & Pharmacotherapy, Journal Year: 2024, Volume and Issue: 179, P. 117302 - 117302

Published: Aug. 19, 2024

Inflammatory bowel disease (IBD), including Crohn's and ulcerative colitis, is a complex disorder with an unknown cause. However, the dysbiosis of gut microbiome has been found to play role in IBD etiology, exacerbated immune responses defective intestinal barrier integrity. The can also be potential biomarker for several diseases, IBD. Currently, conventional treatments targeting pro-inflammatory cytokines pathways IBD-associated do not yield effective results. Other therapies that directly target dysbiotic outcomes are emerging. We review health its as diagnostic, prognostic, therapeutic This explores emerging advancements microbiome-associated alterations IBD, such nanoparticle or encapsulation delivery, fecal microbiota transplantation, nutritional therapies, microbiome/probiotic engineering, phage therapy, mesenchymal stem cells (MSCs), proteins, herbal formulas.

Language: Английский

Citations

15
Effect of Fermented Foods on Inflammatory Bowel Disease: A Focus on the MAPK and NF-kβ Pathways DOI

Ramses Cruz-Valencia,

Lourdes Santiago‐López, Luis Mojica

et al.

ACS Food Science & Technology, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 6, 2025

The aim of this review is to summarize and analyze up date information related the impact fermented dairy plant foods on modulation anti-inflammatory pathways MAPKs NF-κβ associated with inflammatory bowel disease (IBD). This work shows potential modulate MAPK pathways. Also, effect microbiota are discussed. Fermented could act as IBD adjuvants due their bioactive components metabolite content, including peptides, short-chain fatty acids, exopolysaccharides, phenolic compounds, dietary fiber. food metabolites interact key pro-inflammatory cytokines IBD, such ERK 1/2, JNK, p38, p50, p65. Available suggests that compounds from signaling proteins in be used adjuvant treatments for alleviation disease.

Language: Английский

Citations

0
Oral Delivery of 5-Demethylnobiletin by Media-Milled Black Rice Particle-Stabilized Pickering Emulsion Alleviates Colitis in Mice: Synergistic Effects of Carrier and Loaded Bioactive DOI
Hong Hu, Yong Wang,

Deng-Gao Zhao

et al.

Journal of Agricultural and Food Chemistry, Journal Year: 2025, Volume and Issue: 73(2), P. 1257 - 1272

Published: Jan. 7, 2025

Traditional colitis treatment strategies have issues such as side effects and poor lesion targeting. In this study, a milled black rice particle-stabilized Pickering emulsion (BR-5-DMN) has been developed delivery vehicle for 5-demethylnobiletin (5-DMN) to treat colitis. The alleviating of three 5-DMN systems: BR-5-DMN, Tween 80 upper gastrointestinal delivery, soybean oil with most entering the colon were compared. BR-5-DMN exhibited superior effects, enhancing absorption metabolic conversion. It also improved intestinal barrier function microbiome homeostasis, restoring short-chain fatty acid synthesis, especially acetic acid, through releasing dietary fiber, bioactives from rice, in colon. Black particles promoted growth Bifidobacterium while inhibiting Ruminococcus, both synergistically increased Akkermansia abundance. This study highlights potential grain emulsions effective vehicles by regulating release synergistic interactions.

Language: Английский

Citations

0
Fermented pea yoghurt mitigates DSS induced ulcerative colitis through gut microbiota modulation and enhanced SCFA production in a mouse model DOI Creative Commons
Mengdi Zhao, Yuanyuan Zhang, Yi Wu

et al.

Food Bioscience, Journal Year: 2025, Volume and Issue: 65, P. 106046 - 106046

Published: Feb. 2, 2025

Language: Английский

Citations

0
An exploration on the structural characteristics and antioxidant activities of casein hydrolysates fermented by Lactiplantibacillus plantarum A56 and A157 DOI

Cuicui Duan,

Lingfang Zhang, Cheng Wu

et al.

Food Bioscience, Journal Year: 2025, Volume and Issue: unknown, P. 106069 - 106069

Published: Feb. 1, 2025

Language: Английский

Citations

0
Ethanol extract of Lactobacillus rhamnosus AC1-fermented soymilk alleviated DSS-induced colitis via LPS-TLR4-NF-κB signaling pathway DOI Creative Commons
Haicui Wu,

Weijie Fang,

Yuqing Lu

et al.

Journal of Functional Foods, Journal Year: 2025, Volume and Issue: 126, P. 106704 - 106704

Published: Feb. 14, 2025

Language: Английский

Citations

0
Synergistic protective effects of probiotics Lactiplantibacillus plantarum S58 and prebiotics Qingke β-glucan on dextran sulfate sodium-induced cognitive deficits in colitis mice: A study of microbial-gut-brain axis modulation DOI

Yu‐Hang Jiang,

Jiaxin Zhao, Yanlong Li

et al.

Food Bioscience, Journal Year: 2025, Volume and Issue: unknown, P. 106266 - 106266

Published: March 1, 2025

Language: Английский

Citations

0
Preparation, flavor component and antioxidant activity analysis of Lactiplantibacillus plantarum NCU137 fermented rice protein DOI
Zhen Peng,

Baoling Qiao,

Bo Li

et al.

Food Bioscience, Journal Year: 2024, Volume and Issue: 62, P. 105017 - 105017

Published: Aug. 31, 2024

Language: Английский

Citations

3