Tipping Point: Pathogenic Stress and the Biopolitics of Euthanasia DOI
Charles S. Love

The Linacre Quarterly, Journal Year: 2024, Volume and Issue: unknown

Published: Oct. 18, 2024

Hopelessness and demoralization following a terminal diagnosis can affect the capacity for self-governance. Such dispositions increase allostatic load—the cumulative burden of stress anxiety—resulting in neurophysiologic decline that impair autonomy influence desire to end one's life deliberately. An overload is characterized by inability autoregulate associated with pathological changes hypothalamic–pituitary–adrenal axis hippocampus. These raise concerns about reliability concepts extremis, potentially undermining arguments are used justify voluntary euthanasia medically assisted death. Studies have depression hopelessness suicidal ideation general population. However, fewer studies examined how patients without history or may suddenly contemplate act when facing prognosis. This paper will argue an help explain spectrum physical psychological comorbidities onset illness decision hasten Data show disease wishing death typically exhibit lower rates clinical depression, higher demoralization, greater likelihood rational suicide. differences indicate patient population different. Changes autonomous decision-making secondary alterations brain offer explanation. been shown dysregulate executive control functions, specifically intentionality voluntariness. Clinical evidence also indicates spirituality hopefulness manage load during palliative stages so better process end-of-life decisions. Based on these data, this further jurisdictions offering morally compelled make mental spiritual counseling available seeking course action.

Language: Английский

Exposure to warfare and demoralization: acute stress symptoms and disengaged coping as a mediators DOI Creative Commons
Svetlana Baziliansky, Wafaa Sowan

European journal of psychotraumatology, Journal Year: 2025, Volume and Issue: 16(1)

Published: Jan. 13, 2025

Background: Demoralization in the face of adversity is a common existential state. However, it has not been examined reaction to warfare, and mediators between extent exposure war demoralization this context are also unknown.

Language: Английский

Citations

1
Effect of Symptom Burden on Demoralization in Chinese Lung Cancer Patients: The Mediating Roles of Family Function, Resilience, and Coping Behaviors DOI Open Access
Chenxing Zhang, Fangfang Wang,

Zhixuan Kang

et al.

Psycho-Oncology, Journal Year: 2025, Volume and Issue: 34(2)

Published: Feb. 1, 2025

This study aimed to elucidate the mechanisms by which symptom burden affects demoralization in Chinese lung cancer patients, with a focus on roles of family functionality, resilience, and coping strategies. The also explored differences these pathways between two distinct categories. A cross-sectional survey was conducted among 567 patients who completed questionnaires assessing burden, functioning, strategies, demoralization. Data were analyzed using partial least squares structural equation modeling (PLS-SEM), multigroup (MG-SEM) employed compare psychological distress-subjective incompetence group (PDSIG) low demoralization-emotional disturbance (LDEDG). PLS-SEM analysis demonstrated good model fit. Symptom (β = 0.26), confrontation 0.11), acceptance-resignation 0.41) had positive direct effects demoralization, whereas resilience -0.19) function -0.27) negative effects. Additionally, function, mediated relationship MG-SEM revealed that, PDSIG, 0.47) -0.46) similarly strong impacts stronger associated lower In contrast, -1.02) most significant factor LDEDG. These findings highlight importance screening for particularly high maladaptive resignation coping, dysfunction, resilience. Effective strategies should management, support, building, fostering mechanisms. Tailored interventions based subtypes are essential improve well-being this population.

Language: Английский

Citations

0
Incidence and Influencing Factors of Demoralization Syndrome in Elderly Maintenance Hemodialysis Patients: A Multi-Center Cross-Sectional Study DOI Creative Commons
Hong Zhang, Lan Yang, Xiaolong Xing

et al.

International Journal of General Medicine, Journal Year: 2025, Volume and Issue: Volume 18, P. 787 - 797

Published: Feb. 1, 2025

This observational study aimed to investigate the prevalence and influencing factors of demoralization syndrome (DS) in elderly maintenance hemodialysis (MHD) patients, with a focus on improving their psychological distress levels. Convenient sampling was used select 350 MHD patients aged 60 or older from three tertiary hospitals China. Data collected using questionnaires, including Chinese version DS Scale. Statistical analysis conducted SPSS 26.0 software. Single factor revealed that sex, average monthly household income, living alone, dialysis duration, complications, self-care abilities were significant influencers The score moderately high, 59.4% scoring high range. Multivariable linear regression identified self-management as independent impacting DS. highlighted importance addressing enhancing social support, skills, tailoring individualized plans reduce levels alleviate patients. These findings provide valuable insights for healthcare providers aiming enhance patient well-being this population.

Language: Английский

Citations

0
Demoralization and sleep in breast cancer: A casual and computer-simulated network analysis DOI

Hongman Li,

Ying Xiong, Qihan Zhang

et al.

European Journal of Oncology Nursing, Journal Year: 2025, Volume and Issue: unknown, P. 102870 - 102870

Published: March 1, 2025

Language: Английский

Citations

0
Modeling of demoralization in breast cancer DOI Creative Commons
John M. de Figueiredo, Robert Kohn, Joyce Y. Chung

et al.

Frontiers in Psychiatry, Journal Year: 2025, Volume and Issue: 16

Published: April 25, 2025

This study aimed at identifying correlates of demoralization in breast cancer. Information was obtained from outpatients with cancer the Oncology Clinic a university-affiliated hospital United States, using reliable and valid scales, participants' medical records on demographic social characteristics, location, type, stage cancer, whether it re-occurrence or first time diagnosed, type treatment, medications being used, history mental disorder, functional impairment, perceived stress, support, resilience, subjective incompetence, demoralization, depression. Demoralization measured Scale. Bivariable multivariable analyses were conducted as dependent variable. correlated positively depression, negatively months since diagnosed quality life. Forward stepwise regression without depression equation identified emotional wellbeing subscale life, impairment significant. After forced entry support mild ceased to be significant, leaving only moderate severe Perceived stress did not enter any models. Early detection co-occurrence are essential for promoting well-being patients Psychotherapy should focus strengthening modifiable negative countering positive correlates, preventing

Language: Английский

Citations

0
Financial toxicity and its influencing factors in young and middle-aged cancer patients: a latent profile analysis DOI
Xue Lin,

Xiaoyun Teng,

Jie Lan

et al.

Supportive Care in Cancer, Journal Year: 2025, Volume and Issue: 33(5)

Published: April 28, 2025

Language: Английский

Citations

0
Top Ten Tips Palliative Care Clinicians Should Know About the Psychiatric Manifestations of Nonpsychiatric Serious Illness and Treatments DOI
Gregg A. Robbins-Welty, Paul A. Riordan, Daniel Shalev

et al.

Journal of Palliative Medicine, Journal Year: 2024, Volume and Issue: 27(12), P. 1657 - 1665

Published: May 10, 2024

Mental health issues are widespread and significant among individuals with serious illness. Among patients receiving palliative care (PC), psychiatric comorbidities common impact patient quality of life. Despite their prevalence, PC clinicians face challenges in effectively addressing the intricate relationship between medical disorders due to complex, intertwined bidirectionally influential nature. This article, created collaboratively a team psychiatric-palliative experts, is second two-part series examining bidirectional illness PC. article explores 10 prevalent manifestations associated severe its treatment. Building upon first which focused on physical PC, these two articles advocate for an integrated approach that prioritizes mental emotional wellbeing across continuum

Language: Английский

Citations

3
Unrelieved Stress, Decreased Resilience, and Disengagement Coping Strategies Are Associated With Lower Levels of Hope in Patients With Cancer DOI Creative Commons

Laura Allaire,

Astrid Block,

Steven M Paul

et al.

Oncology nursing forum, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 1, 2025

Objectives: To determine clinically meaningful cut points for the Herth Hope Index and evaluate differences in demographic clinical characteristics, as well stress, resilience, coping, between patients with lower versus higher levels of hope.Sample & Setting: Outpatients cancer receiving chemotherapy (N = 1,295).Methods Variables: Patients completed Index, Multidimensional Quality Life Scale–Patient Version, coping measures prior to their second or third cycle chemotherapy.Results: Optimal were 40 less (i.e., level hope) greater than hope). The Lower group had a comorbidity burden functional status.Implications Nursing: Clinicians can use this information educate about interventions that decrease stress improve abilities. may benefit from having conversations clinicians authentically convey prognosis provide realistic sense hope.

Language: Английский

Citations

0
Determinants of Demoralization Syndrome and Social Support Among Patients with Breast Cancer: A Cross-Sectional Study DOI Creative Commons
Yang Li,

Ling-Xia Song,

Lin Zhang

et al.

Journal of Multidisciplinary Healthcare, Journal Year: 2025, Volume and Issue: Volume 18, P. 369 - 379

Published: Jan. 1, 2025

Objective: This study aimed to assess the determinants of demoralization syndrome among patients with breast cancer (BC) in southwestern region China.Methods: investigation constituted a single-center cross-sectional which 176 BC were surveyed through questionnaire covering current status and social support.Results: Majority developed moderate-to-severe levels demoralization.The degree was complex influenced by variety factors.Among BC, demographic variables such as age, education level, residential address, monthly income, occupation, receipt chemotherapy main influencing factors (P < 0.05), whereas children, surgical methods not 0.05).Additionally, all reported receiving support exceeding moderate levels, no statistically significant difference data observed those reporting heightened > 0.05). Conclusion:There are many BC.Nursing interventions play pivotal role minimizing BC.We should pay more attention commitment level.Positive communication patients, involving attentive listening, guidance encouragement, is essential for providing effective psychological care support, fostering trust between healthcare providers patients.

Language: Английский

Citations

0
Clinical Teaching of Demoralization: Challenges and Opportunities DOI
Angela Landerholm,

Damien M. Miran,

Stephanie Tung

et al.

Academic Psychiatry, Journal Year: 2024, Volume and Issue: unknown

Published: July 23, 2024

Language: Английский

Citations

1