Cited by Editorial: Electrical management of heart failure: shaping the future of cardiac pacing and electrophysiology

Transition to Advanced Heart Failure: From Identification to Improving Prognosis DOI

Nikolaos-Iason Tepetes,

Christos Kourek,

Adamantia Papamichail

et al.

Journal of Cardiovascular Development and Disease, Journal Year: 2025, Volume and Issue: 12(3), P. 104 - 104

Published: March 17, 2025

Advanced heart failure (AHF) represents the terminal stage of (HF), characterized by persistent symptoms and functional limitations despite optimal guideline-directed medical therapy (GDMT). This review explores clinical definition, pathophysiology, therapeutic approaches for AHF. Characterized severe symptoms, New York Heart Association (NYHA) class III-IV, significant cardiac dysfunction, frequent hospitalizations, AHF presents substantial challenges in prognosis management. Pathophysiological mechanisms include neurohormonal activation, ventricular remodeling, systemic inflammation, leading to reduced output organ dysfunction. Therapeutic strategies involve a multidisciplinary approach, including pharmacological treatments, device-based interventions like assisted devices, advanced options such as transplantation. Despite progress, management faces limitations, disparities access care need personalized approaches. Novel therapies, artificial intelligence, remote monitoring technologies offer future opportunities improve outcomes. Palliative care, which focuses on symptom relief quality life, remains crucial patients ineligible invasive interventions. Early identification timely intervention are pivotal enhancing survival outcomes this vulnerable population. underscores necessity integrating innovative technologies, medicine, robust palliative into address its high morbidity mortality.

Language: Английский

Citations

Acute Hemodynamic Changes Induced by Cardiac Contractility Modulation Evaluated Using the NICaS® System: A Pilot Study DOI

Andrea Madeo,

Silvana De Bonis,

Anna Lucia Cavaliere

et al.

Journal of Clinical Medicine, Journal Year: 2025, Volume and Issue: 14(7), P. 2172 - 2172

Published: March 22, 2025

Background/Objectives: Heart failure (HF) with reduced ejection fraction remains a significant global health challenge despite advances in medical therapy. Cardiac contractility modulation (CCM) is promising treatment for symptomatic HF patients who are ineligible cardiac resynchronization therapy (CRT). Non-invasive methods to assess the acute hemodynamic effects of CCM critical optimize care and guide treatment. This study aimed evaluate impact on stroke volume (SV) total peripheral resistance index (TPRI) using non-invasive bioimpedance-based system (NICaS®). Methods: Eight (median age: 64.6 years, median left (LVEF): 34.5%) underwent implantation Optimizer Smart Mini device. Hemodynamic parameters, including SV TPRI, were measured NICaS® at baseline (pre-implantation) 1 week, month, 3 months post-implantation. Measurements repeated eight times per session analyzed non-parametric statistical tests, Kruskal-Wallis test, Mann-Whitney Kolmogorov-Smirnov test. Results: Median increased significantly from 40.02 mL (interquartile range (IQR): 32.62-78.16 mL) 69.83 (IQR: 58.63-86.36 (p < 0.0001). TPRI decreased 2537 dn s/cm5 m2 1807-3084 m2) 1307 1119-1665 over same period improved within three implantation. Conclusions: provided reliable, tool monitoring these changes, supporting its use clinical practice.

Language: Английский

Citations

Therapie mit kardialen elektronischen implantierbaren Devices DOI

Jürgen Kuschyk,

Katherine Sattler,

Fabian Fastenrath

et al.

Herz, Journal Year: 2024, Volume and Issue: 49(3), P. 233 - 246

Published: May 6, 2024

Citations

Cardiac contractility modulation in patients with heart failure: the added value of cardiac rehabilitation in identification, management, and follow-up DOI

Matteo Ruzzolini, Francesco Giallauria, Francesco Fattirolli

et al.

International Journal of Cardiology Cardiovascular Risk and Prevention, Journal Year: 2024, Volume and Issue: 21, P. 200284 - 200284

Published: May 16, 2024

Language: Английский

Citations

Revisiting the diagnostic and prognostic significance of high-frequency QRS analysis in cardiovascular diseases: a comprehensive review DOI

Shifeng Qiu,

Tinghui Liu,

Zijin Zhan

et al.

Postgraduate Medical Journal, Journal Year: 2024, Volume and Issue: 100(1189), P. 785 - 795

Published: May 25, 2024

Cardiovascular diseases (CVDs) present a significant global public health threat, contributing to substantial number of cases involving morbidity and mortality. Therefore, the early accurate detection CVDs plays an indispensable role in enhancing patient outcomes. Decades extensive research on electrocardiography at high frequencies have yielded wealth knowledge regarding alterations QRS complex during myocardial ischemia, as well methodologies assess quantify these changes. In recent years, analysis high-frequency (HF-QRS) components has emerged promising non-invasive approach for diagnosing various cardiovascular conditions. Alterations HF-QRS amplitude morphology demonstrated remarkable sensitivity diagnostic indicators often surpassing measures ST-T segment This comprehensive review aims provide intricate overview current advancements, challenges, prospects associated with field CVDs.

Language: Английский

Citations

Beyond Medical Therapy—An Update on Heart Failure Devices DOI

Luigi Falco, Fabio Valente,

Aldo De Falco

et al.

Journal of Cardiovascular Development and Disease, Journal Year: 2024, Volume and Issue: 11(7), P. 187 - 187

Published: June 23, 2024

Heart failure (HF) is a complex and progressive disease marked by substantial morbidity mortality rates, frequent episodes of decompensation, reduced quality life (QoL), with severe financial burden on healthcare systems. In recent years, several large-scale randomized clinical trials (RCTs) have widely expanded the therapeutic armamentarium, underlining additional benefits feasibility rapid titration regimens. This notwithstanding, not declining, hospitalizations are constantly increasing. It acknowledged that even guideline-directed medical therapy (GDMT) board, HF patients prohibitive residual risk, which highlights need for innovative treatment options. this scenario, groundbreaking devices targeting valvular, structural, autonomic abnormalities become crucial tools in management. has led to full-fledged translational boost novel development. Thus, aim review provide an update both approved investigated devices.

Language: Английский

Citations

Cardiac Replacement Therapy: critical issues and future perspectives of Heart Transplantation and Artificial Heart. DOI

Isabella Fumarulo, A. Stefanini, Daniele Masarone

et al.

Current Problems in Cardiology, Journal Year: 2024, Volume and Issue: 50(3), P. 102971 - 102971

Published: Dec. 18, 2024

Language: Английский

Citations

Response to levosimendan predicts response to cardiac contractility modulation therapy: a pilot study DOI

Daniele Masarone, Luigi Falco, Antonio D’Onofrio

et al.

Revista Española de Cardiología (English Edition), Journal Year: 2024, Volume and Issue: 77(8), P. 703 - 705

Published: March 7, 2024

Language: Английский

Citations

La respuesta a levosimendán predice la respuesta a la terapia de modulación de la contractilidad cardiaca: un estudio piloto DOI

Daniele Masarone, Luigi Falco, Antonio D’Onofrio

et al.

Revista Española de Cardiología, Journal Year: 2024, Volume and Issue: 77(8), P. 703 - 705

Published: April 9, 2024

Citations

Editorial: Electrical management of heart failure: shaping the future of cardiac pacing and electrophysiology DOI

Edoardo Bressi,

J. G. L. M. Luermans,

Ahran Arnold

et al.

Frontiers in Cardiovascular Medicine, Journal Year: 2023, Volume and Issue: 10

Published: Nov. 2, 2023

EDITORIAL article Front. Cardiovasc. Med., 02 November 2023Sec. Cardiac Rhythmology Volume 10 - 2023 | https://doi.org/10.3389/fcvm.2023.1325989

Language: Английский

Citations