Folic Acid Deficiency DOI
Bancha Yingngam

Advances in medical diagnosis, treatment, and care (AMDTC) book series, Journal Year: 2024, Volume and Issue: unknown, P. 116 - 164

Published: June 14, 2024

Folic acid deficiency, a critical global health issue, significantly impacts various population groups, particularly pregnant women and individuals with dietary restrictions. This chapter provides an in-depth analysis of folic focusing on its epidemiology, causes, clinical manifestations, including megaloblastic anemia developmental complications. It underscores the crucial role in human physiology, notably DNA synthesis repair. Additionally, discusses complex nature which encompasses inadequacies, malabsorption issues, medication interactions, confronts challenges diagnosis. Management strategies such as modifications, supplementation, public policies, fortification, are thoroughly examined. In conclusion, multifaceted approach is vital for mitigating impact deficiency enhancing outcomes.

Language: Английский

Global Advancements in Bioactive Material Manufacturing for Drug Delivery: A Comprehensive Study DOI Creative Commons
Rafael Leandro Fernandes Melo, Dayana Nascimento Dari, Francisco Izaias da Silva Aires

et al.

ACS Omega, Journal Year: 2025, Volume and Issue: 10(1), P. 1207 - 1225

Published: Jan. 3, 2025

Manufacturing bioactive materials for drug delivery involves developing that interact with biological tissues to release drugs in a controlled and targeted manner. The goal is optimize therapeutic efficacy reduce side effects by combining knowledge from engineering, biology, pharmacology. This study presents detailed bibliometric analysis, exploring the keywords "manufacturing," "bioactive materials," "drug delivery" identify highlight significant advancements field. From Web of Science, 36,504 articles were analyzed, 171 selected deeper identifying key journals, countries, institutions, authors. results field's interdisciplinary nature, grouped into four main themes, including regenerative medicine, scaffolds, three-dimensional (3D) printing, glass, tissue engineering. Future research this area will focus on more effective precise systems using technologies like 3D printing nanotechnology enhance customization control release, aiming efficient therapies.

Language: Английский

Citations

6

Targeted delivery systems of siRNA based on ionizable lipid nanoparticles and cationic polymer vectors DOI
Zhao Yao,

Taiqing Liu,

Jingwen Wang

et al.

Biotechnology Advances, Journal Year: 2025, Volume and Issue: 81, P. 108546 - 108546

Published: Feb. 26, 2025

Language: Английский

Citations

4

Metallic nanoparticles unveiled: Synthesis, characterization, and their environmental, medicinal, and agricultural applications DOI
Mohammad Tahir Aminzai, Metin Yıldırım, Erdal Yabalak

et al.

Talanta, Journal Year: 2024, Volume and Issue: 280, P. 126790 - 126790

Published: Aug. 29, 2024

Language: Английский

Citations

17

Esterification modification of graphene oxide for Metronidazole release: Optimization and modelling using response surface methodology and artificial neural Networks DOI
Niloufar Torabi Fard, Homayon Ahmad Panahi, Elham Moniri

et al.

Journal of Molecular Liquids, Journal Year: 2024, Volume and Issue: 399, P. 124393 - 124393

Published: March 6, 2024

Language: Английский

Citations

13

In Vivo Applications of Dendrimers: A Step toward the Future of Nanoparticle-Mediated Therapeutics DOI Creative Commons
Krzysztof Sztandera, J L Rodríguez-García, Valentı́n Ceña

et al.

Pharmaceutics, Journal Year: 2024, Volume and Issue: 16(4), P. 439 - 439

Published: March 22, 2024

Over the last few years, development of nanotechnology has allowed for synthesis many different nanostructures with controlled sizes, shapes, and chemical properties, dendrimers being best-characterized them. In this review, we present a succinct view structure synthetic procedures used dendrimer synthesis, as well cellular uptake mechanisms by these nanoparticles to gain access cell. addition, manuscript reviews reported in vivo applications drug carriers drugs treatment cancer, neurodegenerative diseases, infections, ocular diseases. The dendrimer-based formulations that have reached phases clinical trials, including safety pharmacokinetic studies, or delivery agents therapeutic compounds are also presented. continuous which makes it possible produce increasingly sophisticated complex indicates fascinating family wide potential pharmaceutical industry, especially systems, number entering trials will markedly increase during coming years.

Language: Английский

Citations

13

Implications of nanotherapeutic advancements to leverage multi-drug resistant breast cancer: The state-of-the-art review DOI Creative Commons

Adhithya Aravindan,

Ashutosh Gupta, Sudheer Moorkoth

et al.

Journal of Drug Delivery Science and Technology, Journal Year: 2024, Volume and Issue: 100, P. 106007 - 106007

Published: Aug. 5, 2024

Globally, cancer is regarded as a severe health issue. Among these breast (BC), the second most common kind in women after skin cancer. According to statistical data from NIH Cancer Institute, expected number of cases was around 3 lakh people, with 7.1 % fatality rate. The rise multidrug resistance (MDR) British Columbia issue it lowers effectiveness existing treatments. Traditional MDR treatment approaches BC have drawbacks, including toxicity, high cost, early discharge, restricted drug load before target, and poor effectiveness. Preventing has depended heavily on developing innovative therapy delivery methods utilizing nanomedicine new diagnosing treating BC. This review discusses its pathophysiology relation tumor kinetics. It focuses latest therapeutic over traditional like Surgery, Chemotherapy, Nanomedicine, Phototherapy, Immunotherapy, Gene therapy. also describes diagnostic techniques using MRI/PET, Mammography, Microwave Sensing, In-silico methods, Molecular techniques, AI-machine learning-based tools. discussed limitations nanoparticles article aims identify efficient ways diagnose treat prevent recurrence.

Language: Английский

Citations

13

Recent advances on chitosan/hyaluronic acid-based stimuli-responsive hydrogels and composites for cancer treatment: A comprehensive review DOI

Fahad Alsaikhan,

Bagher Farhood

International Journal of Biological Macromolecules, Journal Year: 2024, Volume and Issue: unknown, P. 135893 - 135893

Published: Sept. 1, 2024

Language: Английский

Citations

12

Pharmaceutical applications of chitosan in skin regeneration: A review DOI
Jie Wang,

Xunxin Duan,

Donghuo Zhong

et al.

International Journal of Biological Macromolecules, Journal Year: 2023, Volume and Issue: 261, P. 129064 - 129064

Published: Dec. 29, 2023

Language: Английский

Citations

19

Conjugation of folic acid onto poly (acrylic acid-co-allylamine)-grafted mesoporous silica nanoparticles for controlled methotrexate delivery DOI

Nasrollah Jafarpour,

Mohammad Nikpassand, Mehdi Faramarzi

et al.

Journal of Drug Delivery Science and Technology, Journal Year: 2024, Volume and Issue: 96, P. 105667 - 105667

Published: April 17, 2024

Language: Английский

Citations

7

Surface PEGylation of Poly(Ethylenimine) dendrimers grafted magnetic nanoparticles as a pH and magnetic targeting responsive system for Cytarabine drug delivery DOI

Saeed Falah Mashak,

Elham Moniri, Fatemeh Azarakhshi

et al.

Chemical Physics Letters, Journal Year: 2024, Volume and Issue: 857, P. 141722 - 141722

Published: Oct. 25, 2024

Language: Английский

Citations

4