Structural characterization of polysaccharides from Dictyophora rubrovolvata mycelium and their immunostimulatory activity in RAW264.7 cells

Process Biochemistry, Journal Year: 2024, Volume and Issue: 139, P. 22 - 32

Published: Feb. 2, 2024

Language: Английский

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Research Progress of Polysaccharide-Gold Nanocomplexes in Drug Delivery

Pharmaceutics, Journal Year: 2024, Volume and Issue: 16(1), P. 88 - 88

Published: Jan. 9, 2024

Clinical drug administration aims to deliver drugs efficiently and safely target tissues, organs, cells, with the objective of enabling their therapeutic effects. Currently, main approach enhance a drug’s effectiveness is ensuring its efficient delivery intended site. Due fact that there are still various drawbacks traditional methods, such as high toxicity side effects, insufficient specificity, poor targeting, pharmacokinetic performance, nanocarriers have emerged promising alternative. Nanocarriers possess significant advantages in due size tunability surface modifiability. Moreover, nano-drug systems demonstrated strong potential terms prolonging circulation time, improving bioavailability, increasing retention at tumor site, decreasing resistance, well reducing undesirable effects anticancer drugs. Numerous studies focused on utilizing polysaccharides nanodelivery carriers, developing based polysaccharides, or exploiting tumor-targeting ligands precision nanoparticle delivery. These types investigations become commonplace academic literature. This review elucidate preparation methods principles polysaccharide gold nanocarriers. It also provides an overview factors affect loading different kinds Additionally, it outlines strategies employed by improve efficiency The provide reference for further development research systems.

Language: Английский

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Advances in polysaccharide‐based materials for biomedical and pharmaceutical applications: A comprehensive review

Archiv der Pharmazie, Journal Year: 2024, Volume and Issue: unknown

Published: Dec. 9, 2024

Polysaccharides, the most abundant biopolymers in nature, have attracted attention of researchers and clinicians due to its practicality biomedical pharmaceutical sciences. These biomaterials high bioavailability play structural functional roles living organisms. Polysaccharides are classified into several groups based on their origin, including plant polysaccharides marine (like chitosan, hyaluronic acid, dextran, alginates, etc.) with specific applications. possess unique physicochemical (such as surface groups, solubility, stability), mechanical strength tensile), antioxidant activity, biocompatibility, biodegradability, renewability, non-immunogenicity) characteristics which made them excellent platforms for a wide variety Ease extraction different preparation approaches mentioned other potential properties that further improved They drug/bioactive encapsulation capacity sustained/controlled release manner vivo microenvironments. The anti-inflammatory immunomodulation, stimuli-responsive release, passive active delivery considered features these indicated practical applications sciences, biosensors, tissue engineering, implantation, wound healing, vascular grafting, vaccines. This review highlights advances polysaccharide-based materials

Language: Английский

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Preparation and exploration of anti-tumor activity of Poria cocos polysaccharide gold nanorods

International Journal of Biological Macromolecules, Journal Year: 2024, Volume and Issue: 280, P. 135347 - 135347

Published: Sept. 10, 2024

Language: Английский

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A review on structure, bioactivity, mechanism, structure-activity relationship and application of anti-breast cancer polysaccharides

International Journal of Biological Macromolecules, Journal Year: 2024, Volume and Issue: unknown, P. 137043 - 137043

Published: Oct. 1, 2024

Language: Английский

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