Tracheal regeneration and mesenchymal stem cell augmenting potential of natural polyphenol-loaded gelatinmethacryloyl bioadhesive DOI
Subramani Kandhasamy,

Baofang Wu,

Jiayin Wang

et al.

International Journal of Biological Macromolecules, Journal Year: 2024, Volume and Issue: 271, P. 132506 - 132506

Published: May 20, 2024

Language: Английский

Engineered hydrogel platform for diabetic wound healing DOI
Jie Cui, Jianbin Shi, Yanjun Liu

et al.

Chemical Engineering Journal, Journal Year: 2025, Volume and Issue: unknown, P. 160379 - 160379

Published: Feb. 1, 2025

Language: Английский

Citations

0
Bioactive Compounds Produced by Macromycetes for Application in the Pharmaceutical Sector: Patents and Products DOI Creative Commons

Walter José Martínez-Burgos,

Everaldo Montes Montes,

Roberta Pozzan

et al.

Fermentation, Journal Year: 2024, Volume and Issue: 10(6), P. 275 - 275

Published: May 23, 2024

It is widely known that mushrooms present several properties with applications in the medicinal and pharmaceutical sectors, including antimicrobial, immunomodulatory, antioxidant, hypotensive, neuroprotective, anti-inflammatory activities. This article aims to review examples of bioactive metabolites responsible for those activities, such as polysaccharides, phenols polyphenols, terpenes, peptides, alkaloids, steroids, which are produced by relevant mushroom species. also discusses their production through solid-state fermentation submerged fermentation, well processes obtention extracts considerations on stability aiming industrial applications. In addition, examines patent landscape surrounding mushroom-derived bioactives, shedding light intellectual property history innovations driving this field forward. Examples recently deposited patents highlighted, main depositors. China United States major depositor countries (52% 35% patents, respectively), principal compounds polysaccharides alkaloids. The provides insights into current market landscape, showcasing products available consumers. From dietary supplements skincare formulations, offerings reflect growing interest harnessing health benefits bioactives.

Language: Английский

Citations

4
Advances in the development of medical dressings for the treatment of diabetic foot wounds DOI
Ming Cai, Zhao Liu,

Xun Sun

et al.

Chemical Engineering Journal, Journal Year: 2024, Volume and Issue: 498, P. 155575 - 155575

Published: Sept. 7, 2024

Language: Английский

Citations

4
Photo-Crosslinking Hydrogel Based on Porcine Small Intestinal Submucosa Decellularized Matrix/Fish Collagen/GelMA for Culturing Small Intestinal Organoids and Repairing Intestinal Defects DOI Open Access

Zihao Jia,

Ziwei Wang

International Journal of Molecular Sciences, Journal Year: 2025, Volume and Issue: 26(2), P. 663 - 663

Published: Jan. 14, 2025

Organoid technology, as an innovative approach in biomedicine, exhibits promising prospects disease modeling, pharmaceutical screening, regenerative medicine, and oncology research. However, the use of tumor-derived Matrigel primary method for culturing organoids has significantly impeded clinical translation organoid technology due to concerns about potential risks, batch-to-batch instability, high costs. To address these challenges, this study innovatively introduced a photo-crosslinkable hydrogel made from porcine small intestinal submucosa decellularized matrix (SIS), fish collagen (FC), methacrylate gelatin (GelMA). The cost-effective demonstrated excellent biocompatibility, tunable mechanical properties, rapid gelation low immunogenicity. Importantly, proliferation differentiation capacities cultured were comparable those Matrigel, with no significant disparity observed. Furthermore, after one week transplantation nude mice, hydrogel-organoid complex exhibited sustained structural functional stability while preserving characteristics organoids. Our also effective FC/SIS/GelMA accelerating repair process defects, reducing area scar formation, promoting regeneration both villi smooth muscle tissue. In summary, presents novel protocol organoids, offering implications future applications serving experimental foundation development tissue-engineered intestines based on

Language: Английский

Citations

0
Tannic Acid Post-Treatment of Hydrogels Based on Bletilla Striata Polysaccharide and Hyaluronic Acid for Promotion of Diabetic Wound Healing Via Antibacterial and Pro-Angiogenesis DOI
Xiaoli Zhang,

Yujia Yan,

Haibo Xu

et al.

Published: Jan. 1, 2025

Language: Английский

Citations

0
Polydopamine-modified hydroxyapatite and manganese tetroxide nanozyme incorporated gelatin methacryloyl hydrogel: A multifunctional platform for anti-bacteria, immunomodulation, angiogenesis, and enhanced regeneration in infected wounds DOI
Liang Cheng, Huan Zhang, Bingshuai Zhou

et al.

International Journal of Biological Macromolecules, Journal Year: 2025, Volume and Issue: unknown, P. 141834 - 141834

Published: March 1, 2025

Language: Английский

Citations

0
Tracheal regeneration and mesenchymal stem cell augmenting potential of natural polyphenol-loaded gelatinmethacryloyl bioadhesive DOI
Subramani Kandhasamy,

Baofang Wu,

Jiayin Wang

et al.

International Journal of Biological Macromolecules, Journal Year: 2024, Volume and Issue: 271, P. 132506 - 132506

Published: May 20, 2024

Language: Английский

Citations

0