Self-Healing, Electrically Conductive, Antibacterial, and Adhesive Eutectogel Containing Polymerizable Deep Eutectic Solvent for Human Motion Sensing and Wound Healing DOI

Shaghayegh Vakili,

Zahra Mohamadnia, Ebrahim Ahmadi

et al.

Biomacromolecules, Journal Year: 2024, Volume and Issue: unknown

Published: Nov. 14, 2024

Flexible electronic devices such as wearable sensors are essential to advance human-machine interactions. Conductive eutectogels promising for sensors, despite their challenges in self-healing and adhesion properties. This study introduces a multifunctional eutectogel based on novel polymerizable deep eutectic solvent (PDES) prepared by the incorporation of diallyldimethylammonium chloride (DADMAC) glycerol presence polycyclodextrin (PCD)/dopamine-grafted gelatin (Gel-DOP)/oxidized sodium alginate (OSA). The synthesized has reversible Schiff-base bonds, hydrogen host-guest interactions, which enable rapid upon network disruption. GPDO-15 significant tissue adhesion, high stretchability (419%), good ionic conductivity (0.79 mS·cm

Language: Английский

Advancements and applications of upconversion nanoparticles in wound dressings DOI
Hazal Ezgi̇ Gülteki̇n, Gökçen Yaşayan, Ayça Bal‐Öztürk

et al.

Materials Horizons, Journal Year: 2023, Volume and Issue: 11(2), P. 363 - 387

Published: Nov. 2, 2023

Wound healing is a complex process that requires effective management to prevent infections and promote efficient tissue regeneration. In recent years, upconversion nanoparticles (UCNPs) have emerged as promising materials for wound dressing applications due their unique optical properties potential therapeutic functionalities. These possess enhanced antibacterial when functionalized with agents, helping infections, common complication in healing. They can serve carriers controlled drug delivery, enabling targeted release of agents the site, allowing tailored treatment optimal conditions. ability convert near-infrared (NIR) light into visible and/or ultraviolet (UV) regions, making them suitable (photothermal therapy photodynamic therapy) diagnostic applications. context healing, these be combined other such hydrogels, fibers, metal-organic frameworks (MOFs), graphene oxide,

Language: Английский

Citations

19

Application of photocrosslinked gelatin, alginate and dextran hydrogels in the in vitro culture of testicular tissue DOI
Jia Tan, Jiahui Li, Yuqi Zhang

et al.

International Journal of Biological Macromolecules, Journal Year: 2024, Volume and Issue: 260, P. 129498 - 129498

Published: Jan. 15, 2024

Language: Английский

Citations

8

Propolis-Loaded Poly(lactic-co-glycolic Acid) Nanofibers: An In Vitro Study DOI Creative Commons

Fulya Geyik,

Seçil Kaya, Duygu Elif Yılmaz

et al.

ACS Omega, Journal Year: 2024, Volume and Issue: 9(12), P. 14054 - 14062

Published: March 15, 2024

Nanofibers have high potential through their porosity, small pore sizes, lightweight materials, and ability to mimic the extracellular matrix structure for use in manufacture of wound dressings treatment. In this study, poly(lactic-co-glycolic acid) (PLGA) nanofibers were produced by electrospinning. Propolis was loaded into PLGA dropping method. The average diameters effects propolis loading on morphology 37.5, 50, 100% propolis-loaded (PLGA-P37.5, PLGA-P50, PLGA-P100) evaluated scanning electron microscopy (SEM). successful confirmed with Fourier transform infrared spectroscopy (FTIR) analysis. vitro release examined at physiological pH. antioxidant activity studied 2,2-diphenyl-1-picrylhydrazyl (DPPH). Antimicrobial activities against Escherichia coli, Staphylococcus aureus Candida albicans strains determined disk diffusion Consequently, PLGA-P50 PLGA-P100 showed antimicrobial S. C. albicans. Cell viability tested 3-[4,5-dimethylthiazole-2-yl]-2,5-diphenyltetrazolium bromide (MTT) assay, found be biocompatible human fibroblast cells. scratch supported closure cell migration proliferation. Thus, properties first time literature.

Language: Английский

Citations

8

Cyclodextrin nanocarriers in Coordination Chemistry: Enhancing encapsulation and targeted delivery of 5-Fluorouracil for cancer treatment DOI Creative Commons
Sara Payamifar, Amin Foroozandeh, Mehrab Pourmadadi

et al.

Results in Chemistry, Journal Year: 2024, Volume and Issue: 12, P. 101878 - 101878

Published: Oct. 30, 2024

Language: Английский

Citations

8

Curcumin nanopreparations: recent advance in preparation and application DOI
Yan Liu, Rui Yin, Yuan Tian

et al.

Biomedical Materials, Journal Year: 2024, Volume and Issue: 19(5), P. 052009 - 052009

Published: Aug. 27, 2024

Abstract Curcumin is a natural polyphenolic compound extracted from turmeric with antibacterial, antioxidant, antitumor, preventive and therapeutic neurological disorders variety of bioactivities, which widely used in the field food medicine. However, drawbacks curcumin such as poor aqueous solubility stability have limited practical application curcumin. To overcome these defects enhance its functional properties, various nanoscale systems (liposomes, polymer nanoparticles, protein solid lipid metal etc) been extensively employed for encapsulation delivery. Despite rapid development nanoformulations, there lack comprehensive reviews on their preparation properties. This review provides an overview construction nano-delivery systems, mechanisms action, nanocarrier methods applications nanocarriers pharmaceutical fields to provide theoretical basis technological support efficient bio-utilization, product early clinical

Language: Английский

Citations

6

Black phosphorus-based nanoplatforms for cancer therapy: chemistry, design, biological and therapeutic behaviors DOI Creative Commons
Ashkan Bigham, Manuel Serrano‐Ruiz, Maria Caporali

et al.

Chemical Society Reviews, Journal Year: 2024, Volume and Issue: unknown

Published: Dec. 2, 2024

Black phosphorus nanomaterials have opened new doors to cancer therapy. They can induce anticancer activities intrinsically (selectively) and/or with external stimuli (PTT, PDT, SDT, etc. ) and are highly suitable for drug/gene delivery.

Language: Английский

Citations

6

The Combination of Bioactive Herbal Compounds with Biomaterials for Regenerative Medicine DOI
Guoying Zhou, Ruojiao Xu, Thomas Groth

et al.

Tissue Engineering Part B Reviews, Journal Year: 2024, Volume and Issue: 30(6), P. 607 - 630

Published: March 14, 2024

Regenerative medicine aims to restore the function of diseased or damaged tissues and organs by cell therapy, gene tissue engineering, along with adjunctive application bioactive molecules. Traditional molecules such as growth factors cytokines have shown great potential in regulation cellular behavior, but disadvantages limited source, high cost, short half-life, side effects. In recent years, herbal compounds extracted from natural plants/herbs gained increasing attention. This is not only because are easily obtained, inexpensive, mostly safe, reliable, also owing their excellent effects including anti-inflammatory, antibacterial, antioxidative, proangiogenic behavior ability promote stem differentiation. Such play important roles processes related regeneration. Furthermore, moieties can form physical chemical bonds scaffolds, which contributes improved mechanical strength stability scaffolds. Thus, incorporation biomaterials a promising direction for future regenerative applications. Herein, an overview on use combined different biomaterial scaffolds presented. We firstly introduce classification, structures, properties components then provide comprehensive survey engineer repair/regeneration skin, cartilage, bone, neural, heart tissues. Finally, we highlight challenges prospects development toward clinical translation. Overall, it believed that combination could be perspective next generation medicine.

Language: Английский

Citations

5

Benzenesulfonamide-Functionalized Electrospun Polysulfone as an Antibacterial Support Layer of Thin-Film Composite Pressure-Retarded Osmosis Membrane: Fabrication and Performance Evaluation DOI
Alireza Hadipour, Mohamadreza Shakiba, Ali Bozorg

et al.

International Journal of Environmental Research, Journal Year: 2024, Volume and Issue: 18(3)

Published: April 8, 2024

Language: Английский

Citations

5

Sodium alginate/chitosan composite scaffold reinforced with biodegradable polyesters/gelatin nanofibers for cartilage tissue engineering DOI
Chenxi Li, Wenbin Shang, Yuzhe Huang

et al.

International Journal of Biological Macromolecules, Journal Year: 2024, Volume and Issue: unknown, P. 138054 - 138054

Published: Nov. 1, 2024

Language: Английский

Citations

5

3D and 4D printing of MXene-based composites: from fundamentals to emerging applications DOI
Ashkan Bigham, Atefeh Zarepour, Arezoo Khosravi

et al.

Materials Horizons, Journal Year: 2024, Volume and Issue: 11(24), P. 6257 - 6288

Published: Jan. 1, 2024

This review highlights the developments in 3D/4D printing of MXene-based composites, focusing on their application tissue regeneration, drug delivery, sensing, and energy storage.

Language: Английский

Citations

4