The
skin
exhibits
a
hierarchical
structure,
and
the
application
of
tissue
engineering
techniques
is
recommended
for
treatment
severe
cutaneous
injuries.
To
biologically
mimic
structural
characteristics
distinct
layers
skin,
utilization
multilayered
scaffolds
has
become
prominent
approach.
In
current
study,
an
asymmetric
trilayered
scaffold
was
fabricated,
consisting
middle
layer
(ML)
composed
3D
printed
poly(vinyl
alcohol)-carrageenan
(PVA.Crg),
top
(TL)
nanofibrous
polycaprolactone-propolis
(PCL.Pp),
bottom
(BL)
alcohol)-fucoidan-deferoxamine
(PVA.Fu.Def)
nanofibers.
It
indicated
that
tensile
strength
elastic
modulus
trilayer
were
significantly
higher
compared
to
other
samples.
in
vitro
degradation
rate
studied
as
well
release
Def
from
after
7
days
quantified
within
range
36-40
91.1%,
respectively.
did
not
induce
cytotoxicity
chicken
chorioallantoic
membrane
assay
revealed
remarkably
enhanced
angiogenesis.
Furthermore,
vivo
examinations
exhibited
fastest
re-epithelialization
group
treated
with
containing
Def.
findings
this
study
suggest
potential
fabricated
substitute
or
wound
dressing.
Small Methods,
Journal Year:
2024,
Volume and Issue:
8(9)
Published: Feb. 25, 2024
Chitin
and
chitosan-based
bioink
for
3D-printed
flexible
electronics
have
tremendous
potential
innovation
in
healthcare,
agriculture,
the
environment,
industry.
This
biomaterial
is
suitable
3D
printing
because
it
highly
stretchable,
super-flexible,
affordable,
ultrathin,
lightweight.
Owing
to
its
ease
of
use,
on-demand
manufacturing,
accurate
regulated
deposition,
versatility
with
soft
functional
materials,
has
revolutionized
free-form
construction
end-user
customization.
study
examined
employing
chitin
bioinks
build
electronic
devices
optimize
formulation,
parameters,
postprocessing
processes
improve
mechanical
electrical
properties.
The
exploration
bioelectronics
will
open
new
avenues
materials
numerous
industrial
applications.
