Intestinal epithelial cells: regulators of barrier function and immune homeostasis

Nature reviews. Immunology, Journal Year: 2014, Volume and Issue: 14(3), P. 141 - 153

Published: Feb. 25, 2014

Language: Английский

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The Tumor Microenvironment Innately Modulates Cancer Progression

Cancer Research, Journal Year: 2019, Volume and Issue: 79(18), P. 4557 - 4566

Published: July 26, 2019

Cancer development and progression occurs in concert with alterations the surrounding stroma. cells can functionally sculpt their microenvironment through secretion of various cytokines, chemokines, other factors. This results a reprogramming cells, enabling them to play determinative role tumor survival progression. Immune are important constituents stroma critically take part this process. Growing evidence suggests that innate immune (macrophages, neutrophils, dendritic lymphoid myeloid-derived suppressor natural killer cells) as well adaptive (T B contribute when present (TME). Cross-talk between cancer proximal ultimately an environment fosters growth metastasis. Understanding nature dialog will allow for improved therapeutics simultaneously target multiple components TME, increasing likelihood favorable patient outcomes.

Language: Английский

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Cytokines in inflammatory bowel disease

Nature reviews. Immunology, Journal Year: 2014, Volume and Issue: 14(5), P. 329 - 342

Published: April 22, 2014

Language: Английский

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Innate Lymphoid Cells: 10 Years On

Cell, Journal Year: 2018, Volume and Issue: 174(5), P. 1054 - 1066

Published: Aug. 1, 2018

Language: Английский

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The biology of innate lymphoid cells

Nature, Journal Year: 2015, Volume and Issue: 517(7534), P. 293 - 301

Published: Jan. 13, 2015

Language: Английский

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Differentiation of Type 1 ILCs from a Common Progenitor to All Helper-like Innate Lymphoid Cell Lineages

Cell, Journal Year: 2014, Volume and Issue: 157(2), P. 340 - 356

Published: April 1, 2014

Language: Английский

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Guidelines for the use of flow cytometry and cell sorting in immunological studies (second edition)

European Journal of Immunology, Journal Year: 2019, Volume and Issue: 49(10), P. 1457 - 1973

Published: Oct. 1, 2019

These guidelines are a consensus work of considerable number members the immunology and flow cytometry community. They provide theory key practical aspects enabling immunologists to avoid common errors that often undermine immunological data. Notably, there comprehensive sections all major immune cell types with helpful Tables detailing phenotypes in murine human cells. The latest techniques applications also described, featuring examples data can be generated and, importantly, how analysed. Furthermore, tips, tricks pitfalls avoid, written peer-reviewed by leading experts field, making this an essential research companion.

Language: Английский

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Natural killer cells and other innate lymphoid cells in cancer

Nature reviews. Immunology, Journal Year: 2018, Volume and Issue: 18(11), P. 671 - 688

Published: Sept. 12, 2018

Language: Английский

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Tissue-resident memory T cells: local specialists in immune defence

Nature reviews. Immunology, Journal Year: 2015, Volume and Issue: 16(2), P. 79 - 89

Published: Dec. 21, 2015

Language: Английский

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Innate lymphoid cells as regulators of immunity, inflammation and tissue homeostasis

Nature Immunology, Journal Year: 2016, Volume and Issue: 17(7), P. 765 - 774

Published: June 21, 2016

Language: Английский

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