Fritillaria steroidal alkaloids and their multi-target therapeutic mechanisms: insights from network pharmacology DOI
Pankaj Kumar, Vinay Kumar, Shagun Sharma

et al.

Naunyn-Schmiedeberg s Archives of Pharmacology, Journal Year: 2024, Volume and Issue: unknown

Published: Oct. 9, 2024

Language: Английский

Cellular strategies for surviving the alpine extremes: methylerythritol phosphate pathway-driven isoprenoid biosynthesis and stress resilience DOI
Shagun Sharma,

Shivanti Negi,

Pankaj Kumar

et al.

PROTOPLASMA, Journal Year: 2025, Volume and Issue: unknown

Published: April 3, 2025

Language: Английский

Citations

0

Insight into the Genetics and Genomics Studies of the Fritillaria Species DOI
Vinay Kumar, Shagun Sharma, Pankaj Kumar

et al.

Published: Jan. 1, 2024

The plant genus Fritillaria has been used for thousands of years as a source various pharmaceutically active compounds. Research into the genome, molecular phylogeny, and pharmacology species led to discovery wide variety bioactive molecules, including steroidal alkaloids, saponins, terpenoids, glycosides, others. DNA markers have shown be an effective scientific tool determining population structure Fritillaria, making them viable conservation tool. Despite natural selection's common association with growth ecology, very little is known on subject genome size selective pressures that shape it. Selection fundamental drivers growth, such transposable elements gene duplication, may impact many cellular physiological implications huge species. Therapeutic plants bred use conventional biotechnology methods. It time hasten biotech-based breeding techniques these crucial plants. Genetics potential expedite genetic enhancement medicinal via analyses diversity, efforts, propagation, over-production specialized metabolites commercial usage. This chapter presents thorough overview research conducted genetics genomics species, establishing basis plant's sustainable exploitation industrial purposes.

Language: Английский

Citations

3

Harnessing the Power of Aromatic and Medicinal Plants for Natural Product Innovation DOI

Shiuly Bhowmick,

Tanya Singh, Puneet Singh Chauhan

et al.

Published: Jan. 1, 2024

Language: Английский

Citations

2

Uplc-im-q-tof-ms-based biochemometric approach for the identification of insecticidal markers in Fritillaria cirrhosa d.don and elucidation of their insecticidal action DOI
Prateek Singh Bora,

Himanshi Gupta,

Urvashi Kashyap

et al.

Microchemical Journal, Journal Year: 2024, Volume and Issue: unknown, P. 112620 - 112620

Published: Dec. 1, 2024

Language: Английский

Citations

1

Transcriptomic analysis reveals effects of fertilization towards growth and quality of Fritillariae thunbergii bulbus DOI Creative Commons
L Huang, Shuang Liang,

Lei Luo

et al.

PLoS ONE, Journal Year: 2024, Volume and Issue: 19(9), P. e0309978 - e0309978

Published: Sept. 20, 2024

Fritillariae thunbergii Bulbus (FTB) is a traditional Chinese medicine that has been widely cultivated for its expectorant, antitussive, antiasthmatic, antiviral, and anticancer properties. The yield quality of F . are influenced by cultivation conditions, such as the use fertilizers. However, optimal type fertilizers maximum underlying mechanisms not clear. We collected using raw chicken manure (RC), organic fertilizer (OF), plant ash (PA) base in Pan’an County, Jinhua City, Zhejiang Province experimental materials. combined results HPLC-ELSD detection statistics showed with OF application was best, content peimine peiminine reaching 0.0603% 0.0502%, respectively. In addition, 2.70 kg/m 2 Transcriptome analysis indicated up-regulation ABA signaling pathway might promote bulb yield. Furthermore, putative key genes responsible steroidal alkaloid accumulation were identified. These provided guiding significance rational fertilization conditions well basis exploration functional related to biosynthesis pathway.

Language: Английский

Citations

0

Fritillaria steroidal alkaloids and their multi-target therapeutic mechanisms: insights from network pharmacology DOI
Pankaj Kumar, Vinay Kumar, Shagun Sharma

et al.

Naunyn-Schmiedeberg s Archives of Pharmacology, Journal Year: 2024, Volume and Issue: unknown

Published: Oct. 9, 2024

Language: Английский

Citations

0