Current Drug Targets,
Journal Year:
2024,
Volume and Issue:
25(10), P. 649 - 669
Published: June 26, 2024
Breast
cancer
is
a
pervasive
global
health
issue
that
disproportionately
impacts
the
female
population.
Over
past
few
years,
there
has
been
considerable
interest
in
nanotechnology
due
to
its
potential
utility
creating
drug-delivery
systems
designed
combat
this
illness.
The
primary
aim
of
these
devices
enhance
delivery
targeted
medications,
optimise
specific
cells
receive
drugs,
tackle
treatment
resistance
malignant
cells,
and
introduce
novel
strategies
for
preventing
controlling
diseases.
This
research
aims
examine
methodologies
utilised
by
various
carrier
nanoparticles
context
therapeutic
interventions
breast
cancer.
main
objective
investigate
application
technologies
attain
timely
efficient
diagnosis
treatment.
Current
predominantly
examines
diverse
drug
chemotherapeutic
agents.
These
encompass
development
hydrogels,
micelles,
exosomes,
similar
compounds.
analyse
attributes,
intricacies,
notable
advancements,
practical
applications
system
clinical
settings.
Despite
demonstrated
efficacy
methodologies,
an
apparent
discrepancy
can
be
observed
between
progress
made
developing
innovative
approaches
their
widespread
implementation
It
critical
establish
robust
correlation
two
variables
effectiveness
medication
based
on
Therapeutic Delivery,
Journal Year:
2024,
Volume and Issue:
15(4), P. 279 - 303
Published: Feb. 20, 2024
Breast
cancer
(BC)
is
a
heterogeneous
disease
with
various
morphological
features,
clinicopathological
conditions
and
responses
to
different
therapeutic
options,
which
responsible
for
high
mortality
morbidity
in
women.
The
heterogeneity
of
BC
necessitates
new
strategies
diagnosis
treatment,
possible
only
by
cautious
harmonization
the
advanced
nanomaterials.
Recent
developments
vesicular
nanocarrier
therapy
indicate
paradigm
shift
breast
treatment
providing
an
integrated
approach
address
current
issues.
This
review
provides
detailed
classification
nanovesicles
special
emphasis
on
recent
advances,
challenges
translating
nanomaterials
future
potentials.
Next Nanotechnology,
Journal Year:
2024,
Volume and Issue:
6, P. 100074 - 100074
Published: Jan. 1, 2024
This
review
explores
the
integration
of
graphitic
carbon
nitride
(g-C3N4)
with
model
drugs
and
diverse
formulations
to
obtain
nanocomposites
potential
for
cancer
therapy.
Beyond
synthesis,
study
also
deals
cancer-affected
organs,
elucidates
mechanisms
drug
action
categorizes
g-C3N4-based
anti-cancer
compositions.
The
responsive
elements
contributing
inhibition
under
chemotherapeutic
influence
include
reactive
oxygen
species
(ROS),
mitochondrial
potential,
oxidative
stress,
magnetic
responsiveness,
profound
thermal
photo
energy
penetration,
metal
retention
toxicity,
adenosine
triphosphate
(ATP)
blockade
in
cells,
insulating
microenvironments
within
tumours
immune-modulating
antibodies.
Notably,
breast,
prostate,
lung,
ovary
stomach
cancers
owe
their
genesis
exclusively
abnormal
cell
proliferation.
Our
reveals
that
(MD)
ions
(MI)
on
g-C3N4
(g-C3N4/MDMI)
shows
enhanced
biological
activity,
compared
alone.
paper
refers
several
characterization
techniques
decipher
intricate
data
patterns
facilitate
explanations
vitro
analyses
focused
viability
Upon
analysis
all
data,
emerges
as
a
compelling
carrier,
particularly
anticancer
delivery
systems.
not
only
emphasizes
immense
but
paves
way
future
advancements
effective
treatments.
Macromolecular Rapid Communications,
Journal Year:
2024,
Volume and Issue:
45(9)
Published: March 2, 2024
Abstract
Cancer
stands
as
a
leading
cause
of
global
mortality,
with
chemotherapy
being
pivotal
treatment
approach,
either
alone
or
in
conjunction
other
therapies.
The
primary
goal
these
therapies
is
to
inhibit
the
growth
cancer
cells
specifically,
while
minimizing
harm
healthy
dividing
cells.
Conventional
treatments,
often
causing
patient
discomfort
due
side
effects,
have
led
researchers
explore
innovative,
targeted
cell
Thus,
biopolymer‐based
aerogels
emerge
innovative
platforms,
showcasing
unique
properties
that
respond
intelligently
diverse
stimuli.
This
responsiveness
enables
precise
control
over
release
anticancer
drugs,
enhancing
therapeutic
outcomes.
significance
lies
their
ability
offer
drug
delivery
increased
efficacy,
biocompatibility,
and
high
payload.
In
this
comprehensive
review,
author
discuss
role
an
emerging
functionalized
platforms
delivery.
review
addresses
showing
smart
behavior
responding
different
stimuli
including
temperature,
pH,
magnetic
redox
potential
release.
Finally,
discusses
application
aerogel
delivering
drugs
also
gene
applications.
Journal of Complementary and Integrative Medicine,
Journal Year:
2024,
Volume and Issue:
unknown
Published: July 11, 2024
Abstract
Health
care
workers
have
faced
a
significant
challenge
because
of
the
rise
in
cancer
incidence
around
world
during
past
10
years.
Among
various
forms
malignancy
skin
is
most
common,
so
there
need
for
creation
an
efficient
and
safe
treatment
that
may
offer
targeted
site-specific
tumor
penetration,
reduce
unintended
systemic
toxicity.
Nanocarriers
thus
been
employed
to
get
issues
with
traditional
anti-cancer
drug
delivery
methods.
Invasomes
are
lipid-based
nanovesicles
having
small
amounts
terpenes
ethanol
or
mixture
penetrate
more
effectively.
Compared
other
lipid
nanocarriers,
invasomes
at
substantially
faster
rate.
possess
number
advantages,
including
improved
effectiveness,
higher
compliance,
patient
convenience,
advanced
design,
multifunctionality,
enhanced
targeting
capabilities,
non-invasive
methods,
potential
combination
therapies,
ability
overcome
biological
barriers,.
These
attributes
position
as
promising
innovative
platform
future
treatment.
The
current
review
provides
insights
into
invasomes,
fresh
organizational
scheme
incorporates
recent
research,
their
composition,
historical
development
methods
preparation,
penetration
mechanism
involving
effect
formulation
variables
analysis
anticancer
application
invasomes.
Scientific Reports,
Journal Year:
2025,
Volume and Issue:
15(1)
Published: May 26, 2025
This
study
explored
the
development
of
a
novel
colon-specific
drug
delivery
system
for
5-fluorouracil
(5-FU)
using
cross-linked
mastic
gum
(MG)
nanoparticles
(NPs).
The
primary
goal
is
to
enhance
treatment
efficacy
colon
cancer
while
minimizing
systemic
side
effects.
We
employed
Fourier
Transform
Infrared
Radiation
(FTIR)
and
Scanning
Electron
Microscopy
(SEM)
detailed
characterization
samples.
FTIR
analysis
confirmed
successful
cross-linking
MG,
whereas
SEM
images
revealed
spherical
uniform
morphology
NPs.
Additionally,
encapsulation
efficiency
(83.53%),
particle
size
(240
nm),
release
kinetics
(zero-order),
percentage
(95.20%
)
were
analyzed.
results
demonstrated
that
MG
NPs
effectively
encapsulated
controlled
5-FU
in
colon-targeted
manner.
recommends
proposed
because
its
potential
improve
outcomes
treatment.
