Recent Advances in Antibacterial Coatings to Combat Orthopedic Implant-Associated Infections

Molecules, Journal Year: 2024, Volume and Issue: 29(5), P. 1172 - 1172

Published: March 6, 2024

Implant-associated infections (IAIs) represent a major health burden due to the complex structural features of biofilms and their inherent tolerance antimicrobial agents immune system. Thus, viable options eradicate embedded on medical implants are surgical operations long-term repeated antibiotic courses. Recent years have witnessed growing interest in development robust reliable strategies for prevention treatment IAIs. In particular, it seems promising develop materials with anti-biofouling antibacterial properties combating IAIs implants. this contribution, we exclusively focus recent advances modified functionalized implant surfaces inhibiting bacterial attachment eventually biofilm formation orthopedic Further, highlight progress coatings (including self-assembled nanocoatings) preventing Among recently introduced approaches efficient durable coatings, use safe biocompatible excellent activities local delivery combinatorial treating overcoming resistance.

Language: Английский

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Evaluation of biofilm formation on acrylic resins used to fabricate dental temporary restorations with the use of 3D printing technology

BMC Oral Health, Journal Year: 2022, Volume and Issue: 22(1)

Published: Oct. 13, 2022

Temporary implant-retained restorations are required to support function and esthetics of the masticatory system until final restoration is completed delivered. Acrylic resins commonly used in prosthetic dentistry lately they have been three-dimensional (3D) printing technology. Since this technology it fairly new, number studies on their susceptibility microbial adhesion low. Restorations placed even for a short period time may become reservoir microorganisms that affect peri-implant tissues trigger inflammation endangering further procedures. The aim study was test biofilm formation acrylamide fabricate temporary 3D assess if post-processing impacts adhesion.Disk-shaped samples were manufactured using technique from three commercially available UV-curable consisting acrylate methacrylate oligomers with various inhibitors polymerization (NextDent MFH bleach, NextDent Plus, MazicD Temp). tested raw, polished glazed. ability create by oral streptococci (S. mutans, S. sanguinis, oralis, mitis) tested, as well species higher pathogenic potential: Staphylococcus aureus, epidermidis Candida albicans. roughness materials measured an atomic force microscope. Biofilm assessed after 72 h incubation crystal violet staining absorbance measurement, quantification viable microorganisms, imaging scanning electron microscope (SEM).Each formed all resins. Post-production processing resulted reduced parameters abundance. Polishing glazing significantly resin group, while alone caused significant surface smoothing Mazic Temp. A thin layer covered glazed surfaces small strains except oralis epidermidis, raw dense biofilm, rich microorganisms.UV-curing acrylic fabricating interim solution, but susceptible streptococci, staphylococci Candida. Post-processing particularly process reduce bacterial risk failure restoration.

Language: Английский

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Evaluation of the Properties of 3D-Printed Ti Alloy Plates: In Vivo and In Vitro Comparative Experimental Study

Journal of Clinical Medicine, Journal Year: 2023, Volume and Issue: 12(2), P. 444 - 444

Published: Jan. 5, 2023

Titanium (Ti)-based implants play a significant role in rigid internal fixation maxillofacial surgery. No study has reported that three-dimensional-printed Ti alloy plates (3D-Ti plates) have comprehensively excellent properties similar to standard (Matrix-MANDIBLE, SYNTHES, Switzerland) (Synthes-Ti plates). In this work, we manufactured 3D-Ti by selective laser melting with Ti6Al4V powder. The surface morphology, mechanical properties, and bone-plate contact rate of the Synthes-Ti were characterized compared via electron microscopy, atomic force Vickers hardness test, three-point bending software calculation. Human bone marrow stromal cells (HBMSCs) cultured on test their biocompatibility. Importantly, placed into mandibular fracture model assess effect medical application for 4 24 weeks. demonstrated biocompatibility stability plates, lower roughness (106.44 ± 78.35 nm), better strength (370.78 1.25 HV10), higher (96.9%). These promising results indicate feasibility using irregular shapes complex anatomical structures clinical context.

Language: Английский

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A Relationship Between Manufacturing Routes-Microstructure-Biotribology of Selective Laser Melted Stainless Steel 316L Under Dry and Simulated Body Fluid

International Journal of Precision Engineering and Manufacturing-Green Technology, Journal Year: 2023, Volume and Issue: 11(4), P. 1147 - 1161

Published: Dec. 19, 2023

Language: Английский

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Poly (α-caprolactone) (PCL) biopolymeric bionanoarchitectures for tissue engineering applications

International Journal of Polymeric Materials, Journal Year: 2024, Volume and Issue: unknown, P. 1 - 30

Published: July 10, 2024

Language: Английский

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Revolutionizing Orthopaedic Surgery: The Impact of 3D Printed Implants and Patient-Specific Instrumentation

Published: Jan. 1, 2025

Language: Английский

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Primary Orbital Reconstruction with Selective Laser Melting (SLM) of Patient-Specific Implants (PSIs): An Overview of 96 Surgically Treated Patients

Journal of Clinical Medicine, Journal Year: 2022, Volume and Issue: 11(12), P. 3361 - 3361

Published: June 11, 2022

Contemporary advances in technology have allowed the transfer of knowledge from industrial laser melting systems to surgery; such an approach could increase degree accuracy orbital restoration. The aim this study was examine selective melted PSIs (patient-specific implants) and navigation primary reconstruction. Ninety-six patients with fractures were included study. Planned vs. achieved volumes (a) angles (b) compared unaffected side (n = 96). analysis overlay post-treatment on planned images (iPlan 3.0.5, Brainlab®, Feldkirchen, Germany). mean difference volume between digitally orbit postoperative 29.16 cm3 (SD 3.54, presurgical) 28.33 3.64, postsurgical, t 5.00, df 95.00; p < 0.001), resulting a (planned postop) less than 1 cm3. A 3D color mapping showed minor deviations mirrored side. results suggested that reconstruction complex wall can be routinely high by using PSIs.

Language: Английский

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Greener Approaches to Combat Biofilm’s Antimicrobial Resistance On 3D Printed Materials: A Systematic Review

Published: Jan. 19, 2024

In recent years, Additive Manufacturing (AM), commonly referred to as 3D printing, has garnered the attention of scientific community due its capacity transform ordinary and traditional items into customized materials at an affordable cost, through various AM processes. Antimicrobial/antibiofilm printed are one most trending research topics, owing growing concerns over emergence complex microbial structures called "biofilms" on surfaces. The review provides overview evolution additive manufacturing (AM) technologies their derivatives, along with a brief description applications. It also introduces how biofilms can represent advantageous lifestyle for populations. primary objective this was conduct systematic development planctonic or biofilm forms microorganisms materials. article summarizes studied these presents printing process, materials, well fields covered by each analyzed papers. To best our knowledge, is first all-inclusive that amalgamated conducted in diverse assess surfaces produced three-dimensional printing. Most notably, comprehensive account sustainable approaches producing antimicrobial Additionally, we advancements such medicine, environment, agri-food, other relevant sectors. findings literature be used recommend appropriate microorganisms, academic industrial purposes focusing Furthermore, it highlights potential environmentally-friendly modified combat clinical non-clinical areas. Our goal help readers gain better understanding fundamental concepts, inspire new researchers, provide valuable insights future empirical studies focused eradicating from

Language: Английский

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Comparative study on surface wettability, bio-tribology, and cytotoxicity of selective laser melted 316L SS, CoCrMo, and Ti6Al4V metallic biomaterials

Manufacturing Letters, Journal Year: 2024, Volume and Issue: 41, P. 947 - 954

Published: Oct. 1, 2024

Language: Английский

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Effect of tea tree oil addition on the microstructure, structure and selected properties of chitosan-based coatings electrophoretically deposited on zirconium alloy substrates

Applied Surface Science, Journal Year: 2022, Volume and Issue: 609, P. 155266 - 155266

Published: Oct. 14, 2022

In this work, Tea Tree Oil (TTO)/chitosan coatings of different TTO concentrations were electrophoretically deposited (EPD) on Zr-2.5Nb alloy substrates. The properties solutions and EPD kinetics TTO/chitosan pure chitosan used as a reference material analysed. incorporation into changed their zeta potential conductivity, well influencing the kinetics. microstructure consisted droplets embedded matrix. addition resulted in formation new hydrogen bonds between main components. Both from containing up to 10 mL/L had excellent adhesion rough mechanical interlocking was indicated mechanism coatings. However, chemical bonding not excluded. exhibited hydrophobic character showed about 50% lower SFE with very low value polar component compared obtained results characterisation microstructure, structure selected show that are promising antimicrobial for metallic biomaterial cytotoxicity should be further investigated.

Language: Английский

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