The Journal of Clinical Endocrinology & Metabolism,
Journal Year:
2023,
Volume and Issue:
108(7), P. 1824 - 1834
Published: Jan. 26, 2023
Abstract
Context
It
remains
controversial
whether
the
choice
of
daily
eating
window
early
or
later
in
time-restricted
(TRE)
intervention
(early
TRE)
has
different
effects
on
weight
loss
and
metabolic
health.
Objective
A
network
meta-analysis
was
performed
to
evaluate
efficacy
between
TRE
adults
with
obesity
overweight.
Methods
We
searched
PubMed,
Embase,
Web
Science,
Cochrane
Library
for
randomized
controlled
trials
(RCTs)
published
until
October
16,
2022.
conducted
a
body
parameters,
including
glycemic
metabolism,
blood
pressure,
lipid
profiles.
Results
Twelve
RCTs
730
obese
overweight
were
included
this
meta-analysis.
Early
both
elicited
moderate
reductions
insulin
resistance
(IR)
(homeostasis
model
assessment
IR)
when
compared
non-TRE.
Interestingly,
showed
more
effectiveness
than
improving
IR
vs
TRE:
−0.44;
95%
CI,
−0.86
−0.02;
P
<
.05),
whereas
no
statistically
significant
difference
detected
−0.31
kg;
−1.15
0.53
>.05).
In
addition,
rather
benefits
metabolism
pressure
No
differences
observed
fasting
glucose,
Conclusion
This
suggests
that
people
may
choose
effective
management
benefits.
Nevertheless,
further
large-scale
are
warranted
verify
our
findings.
Gut,
Journal Year:
2023,
Volume and Issue:
72(8), P. 1607 - 1619
Published: June 7, 2023
Non-alcoholic
fatty
liver
disease
(NAFLD)
represents
a
major
public
health
concern
and
is
associated
with
substantial
global
burden
of
liver-related
cardiovascular-related
morbidity
mortality.
High
total
energy
intake
coupled
unhealthy
consumption
ultra-processed
foods
saturated
fats
have
long
been
regarded
as
dietary
drivers
NAFLD.
However,
there
an
accumulating
body
evidence
demonstrating
that
the
timing
across
day
also
important
determinant
individual
risk
for
NAFLD
metabolic
conditions.
This
review
summarises
available
observational
epidemiological
data
describing
associations
between
eating
patterns
disease,
including
negative
effects
irregular
meal
patterns,
skipping
breakfast
night-time
on
health.
We
suggest
these
harmful
behaviours
deserve
greater
consideration
in
stratification
management
patients
particularly
24-hour
society
continuous
availability
food
up
to
20%
population
now
engaged
shiftwork
mistimed
patterns.
draw
studies
reporting
liver-specific
impact
Ramadan,
which
unique
real-world
opportunity
explore
physiological
fasting.
By
highlighting
from
preclinical
pilot
human
studies,
we
present
further
biological
rationale
manipulating
improve
discuss
how
this
may
be
mediated
through
restoration
natural
circadian
rhythms.
Lastly,
comprehensively
landscape
trials
intermittent
fasting
time-restricted
offer
look
future
about
strategies
benefit
non-alcoholic
steatohepatitis.
Frontiers in Nutrition,
Journal Year:
2023,
Volume and Issue:
10
Published: April 17, 2023
Obesity
is
associated
with
low-grade
inflammation.
Weight
loss,
by
means
of
dietary
restriction,
has
been
shown
to
reduce
systemic
Intermittent
fasting
recently
gained
popularity
as
a
weight
loss
diet,
but
its
effects
on
inflammatory
markers
in
individuals
obesity
have
yet
be
summarized.
Accordingly,
this
review
examined
how
the
two
main
forms
intermittent
fasting,
i.e.,
time
restricted
eating
(TRE)
and
alternate
day
(ADF),
impact
body
key
circulating
(i.e.,
C-reactive
protein
(CRP),
tumor
necrosis
factor-alpha
(TNF-alpha),
interleukin-6
(IL-6)),
adults
obesity.
Results
from
reveal
that
TRE
various
window
durations
(4–10
h
per
day)
no
effect
levels
CRP,
TNF-alpha
or
IL-6,
1–5%
loss.
As
for
ADF,
reductions
CRP
concentrations
were
noted
when
>6%
was
achieved.
However,
ADF
had
IL-6
concentrations,
degree
Thus,
little
markers,
more
research
warranted
confirm
these
preliminary
findings.
iScience,
Journal Year:
2024,
Volume and Issue:
27(2), P. 109000 - 109000
Published: Jan. 26, 2024
Time-restricted
eating
(TRE)
is
an
effective
way
to
lose
weight
and
improve
metabolic
health
in
animals.
Yet
whether
how
these
benefits
apply
humans
unclear.
This
systematic
review
meta-analysis
examined
the
effect
of
TRE
people
with
overweight
obesity
statuses.
The
results
showed
that
led
modest
loss,
lower
waist
circumference
energy
deficits.
also
improved
body
mass
index,
fat
mass,
lean
systolic
blood
pressure,
fasting
glucose
levels,
insulin
HbA1c%.
Subgroup
analysis
demonstrated
more
improvements
group
than
control
under
Obesity,
Journal Year:
2022,
Volume and Issue:
31(S1), P. 96 - 107
Published: Dec. 14, 2022
Abstract
Objective
Data
are
mixed
on
whether
intermittent
fasting
improves
weight
loss
and
cardiometabolic
health.
Here,
the
effects
of
time‐restricted
eating
(TRE)
in
participants
who
consistently
adhered
≥5
d/wk
every
week
were
analyzed.
Methods
Ninety
patients
aged
25
to
75
years
old
with
obesity
randomized
early
TRE
(eTRE;
8‐hour
window
from
07:00
15:00)
or
a
control
schedule
(≥12‐hour
window)
for
14
weeks.
A
per‐protocol
analysis
loss,
body
composition,
health,
other
end
points
was
performed.
Results
Participants
eTRE
had
greater
improvements
(−3.7
±
1.2
kg;
p
=
0.003),
fat
(−2.8
1.3
0.04),
heart
rate
(−7
3
beats/min;
0.02),
insulin
resistance
(−2.80
1.36;
0.047),
glucose
(−9
5
mg/dL;
0.047)
relative
adherers
group.
They
also
experienced
mood,
including
fatigue
anger;
however,
they
self‐reported
sleeping
less
taking
longer
fall
asleep.
Conclusions
For
those
can
adhere
at
least
d/wk,
is
valuable
approach
improving
weight,
fat,
mood.
Further
research
needed
determine
eTRE's
shortening
sleep
but
reducing
healthful
not.
Obesity,
Journal Year:
2023,
Volume and Issue:
31(6), P. 1463 - 1485
Published: May 19, 2023
Abstract
Objective
This
systematic
scoping
review
aimed
to
map
and
synthesize
research
on
feasibility
of
time‐restricted
eating
(TRE)
in
individuals
with
overweight,
obesity,
prediabetes,
or
type
2
diabetes,
including
recruitment
rate,
retention
safety,
adherence,
participants'
attitudes,
experiences,
perspectives.
Methods
The
authors
searched
MEDLINE,
Embase,
Cumulative
Index
Nursing
Allied
Health
Literature
from
inception
November
22,
2022,
supplemented
by
backward
forward
citation
search.
Results
From
4219
identified
records,
28
studies
were
included.
In
general,
was
easy
median
rate
95%
among
<12
weeks
duration
89%
≥12
weeks.
Median
(range)
adherence
the
target
window
for
(75%–98%)
81%
(47%–93%),
respectively.
Variation
participants
considerable,
indicating
that
following
TRE
difficult
some
people
intervention
conditions
influenced
adherence.
These
findings
supported
qualitative
data
synthetized
seven
studies,
determinants
included
calorie‐free
beverages
outside
window,
provision
support,
influence
window.
No
serious
adverse
events
reported.
Conclusions
is
implementable,
acceptable,
safe
populations
but
it
should
be
accompanied
support
options
individual
adjustments.
