International Journal of Behavioral Nutrition and Physical Activity, Год журнала: 2024, Номер 21(1)
Опубликована: Сен. 26, 2024
Язык: Английский
Cell Metabolism, Год журнала: 2024, Номер 36(2), С. 301 - 314
Опубликована: Янв. 3, 2024
Язык: Английский
Процитировано
44
The Journal of Clinical Endocrinology & Metabolism, Год журнала: 2023, Номер 108(7), С. 1824 - 1834
Опубликована: Янв. 26, 2023
Abstract Context It remains controversial whether the choice of daily eating window early or later in time-restricted (TRE) intervention (early TRE) has different effects on weight loss and metabolic health. Objective A network meta-analysis was performed to evaluate efficacy between TRE adults with obesity overweight. Methods We searched PubMed, Embase, Web Science, Cochrane Library for randomized controlled trials (RCTs) published until October 16, 2022. conducted a body parameters, including glycemic metabolism, blood pressure, lipid profiles. Results Twelve RCTs 730 obese overweight were included this meta-analysis. Early both elicited moderate reductions insulin resistance (IR) (homeostasis model assessment IR) when compared non-TRE. Interestingly, showed more effectiveness than improving IR vs TRE: −0.44; 95% CI, −0.86 −0.02; P < .05), whereas no statistically significant difference detected −0.31 kg; −1.15 0.53 >.05). In addition, rather benefits metabolism pressure No differences observed fasting glucose, Conclusion This suggests that people may choose effective management benefits. Nevertheless, further large-scale are warranted verify our findings.
Язык: Английский
Процитировано
41
Nature Medicine, Год журнала: 2025, Номер unknown
Опубликована: Янв. 7, 2025
Язык: Английский
Процитировано
2
Gut, Год журнала: 2023, Номер 72(8), С. 1607 - 1619
Опубликована: Июнь 7, 2023
Non-alcoholic fatty liver disease (NAFLD) represents a major public health concern and is associated with substantial global burden of liver-related cardiovascular-related morbidity mortality. High total energy intake coupled unhealthy consumption ultra-processed foods saturated fats have long been regarded as dietary drivers NAFLD. However, there an accumulating body evidence demonstrating that the timing across day also important determinant individual risk for NAFLD metabolic conditions. This review summarises available observational epidemiological data describing associations between eating patterns disease, including negative effects irregular meal patterns, skipping breakfast night-time on health. We suggest these harmful behaviours deserve greater consideration in stratification management patients particularly 24-hour society continuous availability food up to 20% population now engaged shiftwork mistimed patterns. draw studies reporting liver-specific impact Ramadan, which unique real-world opportunity explore physiological fasting. By highlighting from preclinical pilot human studies, we present further biological rationale manipulating improve discuss how this may be mediated through restoration natural circadian rhythms. Lastly, comprehensively landscape trials intermittent fasting time-restricted offer look future about strategies benefit non-alcoholic steatohepatitis.
Язык: Английский
Процитировано
38
Frontiers in Nutrition, Год журнала: 2023, Номер 10
Опубликована: Апрель 17, 2023
Obesity is associated with low-grade inflammation. Weight loss, by means of dietary restriction, has been shown to reduce systemic Intermittent fasting recently gained popularity as a weight loss diet, but its effects on inflammatory markers in individuals obesity have yet be summarized. Accordingly, this review examined how the two main forms intermittent fasting, i.e., time restricted eating (TRE) and alternate day (ADF), impact body key circulating (i.e., C-reactive protein (CRP), tumor necrosis factor-alpha (TNF-alpha), interleukin-6 (IL-6)), adults obesity. Results from reveal that TRE various window durations (4–10 h per day) no effect levels CRP, TNF-alpha or IL-6, 1–5% loss. As for ADF, reductions CRP concentrations were noted when >6% was achieved. However, ADF had IL-6 concentrations, degree Thus, little markers, more research warranted confirm these preliminary findings.
Язык: Английский
Процитировано
24
Trends in Endocrinology and Metabolism, Год журнала: 2024, Номер 35(9), С. 821 - 833
Опубликована: Май 8, 2024
Язык: Английский
Процитировано
12
iScience, Год журнала: 2024, Номер 27(2), С. 109000 - 109000
Опубликована: Янв. 26, 2024
Time-restricted eating (TRE) is an effective way to lose weight and improve metabolic health in animals. Yet whether how these benefits apply humans unclear. This systematic review meta-analysis examined the effect of TRE people with overweight obesity statuses. The results showed that led modest loss, lower waist circumference energy deficits. also improved body mass index, fat mass, lean systolic blood pressure, fasting glucose levels, insulin HbA1c%. Subgroup analysis demonstrated more improvements group than control under
Язык: Английский
Процитировано
8
Diabetes & Metabolic Syndrome Clinical Research & Reviews, Год журнала: 2024, Номер 18(2), С. 102952 - 102952
Опубликована: Фев. 1, 2024
Язык: Английский
Процитировано
8
Obesity, Год журнала: 2022, Номер 31(S1), С. 96 - 107
Опубликована: Дек. 14, 2022
Abstract Objective Data are mixed on whether intermittent fasting improves weight loss and cardiometabolic health. Here, the effects of time‐restricted eating (TRE) in participants who consistently adhered ≥5 d/wk every week were analyzed. Methods Ninety patients aged 25 to 75 years old with obesity randomized early TRE (eTRE; 8‐hour window from 07:00 15:00) or a control schedule (≥12‐hour window) for 14 weeks. A per‐protocol analysis loss, body composition, health, other end points was performed. Results Participants eTRE had greater improvements (−3.7 ± 1.2 kg; p = 0.003), fat (−2.8 1.3 0.04), heart rate (−7 3 beats/min; 0.02), insulin resistance (−2.80 1.36; 0.047), glucose (−9 5 mg/dL; 0.047) relative adherers group. They also experienced mood, including fatigue anger; however, they self‐reported sleeping less taking longer fall asleep. Conclusions For those can adhere at least d/wk, is valuable approach improving weight, fat, mood. Further research needed determine eTRE's shortening sleep but reducing healthful not.
Язык: Английский
Процитировано
32
Obesity, Год журнала: 2023, Номер 31(6), С. 1463 - 1485
Опубликована: Май 19, 2023
Abstract Objective This systematic scoping review aimed to map and synthesize research on feasibility of time‐restricted eating (TRE) in individuals with overweight, obesity, prediabetes, or type 2 diabetes, including recruitment rate, retention safety, adherence, participants' attitudes, experiences, perspectives. Methods The authors searched MEDLINE, Embase, Cumulative Index Nursing Allied Health Literature from inception November 22, 2022, supplemented by backward forward citation search. Results From 4219 identified records, 28 studies were included. In general, was easy median rate 95% among <12 weeks duration 89% ≥12 weeks. Median (range) adherence the target window for (75%–98%) 81% (47%–93%), respectively. Variation participants considerable, indicating that following TRE difficult some people intervention conditions influenced adherence. These findings supported qualitative data synthetized seven studies, determinants included calorie‐free beverages outside window, provision support, influence window. No serious adverse events reported. Conclusions is implementable, acceptable, safe populations but it should be accompanied support options individual adjustments.
Язык: Английский
Процитировано
18