Published: Jan. 1, 2024
Language: Английский
Diabetes Care, Journal Year: 2023, Volume and Issue: 47(Supplement_1), P. S77 - S110
Published: Dec. 11, 2023
The American Diabetes Association (ADA) "Standards of Care in Diabetes" includes the ADA's current clinical practice recommendations and is intended to provide components diabetes care, general treatment goals guidelines, tools evaluate quality care. Members ADA Professional Practice Committee, an interprofessional expert committee, are responsible for updating Standards annually, or more frequently as warranted. For a detailed description standards, statements, reports, well evidence-grading system full list Committee members, please refer Introduction Methodology. Readers who wish comment on invited do so at professional.diabetes.org/SOC.
Language: Английский
Citations
145
Sleep Medicine Reviews, Journal Year: 2024, Volume and Issue: 75, P. 101926 - 101926
Published: March 21, 2024
The number of individuals experiencing sleep loss has exponentially risen over the past decades. Extrapolation laboratory findings to real world suggests that females are more affected by extended wakefulness and circadian misalignment than males are. Therefore, long-term effects such as metabolism disorders likely be prevalent in males. Despite emerging evidence for sex differences key aspects sleep-wake regulation, much remains unknown, often underrepresented research. This brief communication is intended highlight 1) how systematically impinge on regulation humans, 2) factors modulate metabolism, 3) meaning these precision medicine. Ultimately, justify factoring when optimizing individually targeted interventions humans.
Language: Английский
Citations
36
Diabetes Care, Journal Year: 2024, Volume and Issue: 48(Supplement_1), P. S86 - S127
Published: Dec. 9, 2024
The American Diabetes Association (ADA) "Standards of Care in Diabetes" includes the ADA's current clinical practice recommendations and is intended to provide components diabetes care, general treatment goals guidelines, tools evaluate quality care. Members ADA Professional Practice Committee, an interprofessional expert committee, are responsible for updating Standards annually, or more frequently as warranted. For a detailed description standards, statements, reports, well evidence-grading system full list Committee members, please refer Introduction Methodology. Readers who wish comment on invited do so at professional.diabetes.org/SOC.
Language: Английский
Citations
19
Nature Medicine, Journal Year: 2025, Volume and Issue: unknown
Published: Jan. 7, 2025
Language: Английский
Citations
2
Gut, Journal Year: 2023, Volume and Issue: 72(8), P. 1607 - 1619
Published: June 7, 2023
Non-alcoholic fatty liver disease (NAFLD) represents a major public health concern and is associated with substantial global burden of liver-related cardiovascular-related morbidity mortality. High total energy intake coupled unhealthy consumption ultra-processed foods saturated fats have long been regarded as dietary drivers NAFLD. However, there an accumulating body evidence demonstrating that the timing across day also important determinant individual risk for NAFLD metabolic conditions. This review summarises available observational epidemiological data describing associations between eating patterns disease, including negative effects irregular meal patterns, skipping breakfast night-time on health. We suggest these harmful behaviours deserve greater consideration in stratification management patients particularly 24-hour society continuous availability food up to 20% population now engaged shiftwork mistimed patterns. draw studies reporting liver-specific impact Ramadan, which unique real-world opportunity explore physiological fasting. By highlighting from preclinical pilot human studies, we present further biological rationale manipulating improve discuss how this may be mediated through restoration natural circadian rhythms. Lastly, comprehensively landscape trials intermittent fasting time-restricted offer look future about strategies benefit non-alcoholic steatohepatitis.
Language: Английский
Citations
38
Translational Neurodegeneration, Journal Year: 2024, Volume and Issue: 13(1)
Published: April 2, 2024
Abstract Huntington's disease (HD) is a devastating neurodegenerative disorder caused by aggregation of the mutant huntingtin (mHTT) protein, resulting from CAG repeat expansion in gene HTT . HD characterized variety debilitating symptoms including involuntary movements, cognitive impairment, and psychiatric disturbances. Despite considerable efforts, effective disease-modifying treatments for remain elusive, necessitating exploration novel therapeutic approaches, lifestyle modifications that could delay symptom onset progression. Recent studies suggest time-restricted eating (TRE), form intermittent fasting involving daily caloric intake within limited time window, may hold promise treatment diseases, HD. TRE has been shown to improve mitochondrial function, upregulate autophagy, reduce oxidative stress, regulate sleep–wake cycle, enhance function. In this review, we explore potential role HD, focusing on its underlying physiological mechanisms. We discuss how might clearance mHTT, recover striatal brain-derived neurotrophic factor levels, function stress-response pathways, synchronize circadian rhythm activity. Understanding these mechanisms critical development targeted interventions mitigate pathology patient outcomes. While benefits animal models are encouraging, future comprehensive clinical trials will be necessary evaluate safety, feasibility, efficacy persons with
Language: Английский
Citations
11
Nutrients, Journal Year: 2024, Volume and Issue: 16(3), P. 357 - 357
Published: Jan. 25, 2024
The efficacy of intermittent fasting (IF), as an emerging weight management strategy, in improving cardiometabolic health has been evaluated various populations, but that among Chinese individuals not systematically studied. A comprehensive search on multiple databases was performed to identify eligible randomized controlled trials (RCTs) up October 2022. primary outcome post-intervention loss, and secondary outcomes included changes indicators. Effect estimates were meta-analyzed using a random-effects model. In total, nine RCTs with 899 participants included. Time-restricted eating the most adopted IF protocol this study (six out nine), followed by alternate-day fasting. intervention significantly reduced body weight, mass index, fat mass, homeostatic model assessment insulin resistance, low-density lipoprotein cholesterol, triglycerides when compared control groups. However, no statistically significant reductions waist circumference, total high-density glucose, systolic blood pressure, diastolic pressure found. To sum up, can be strategy may improve adults, more long-term different strategies are required generate robust evidence its efficacy.
Language: Английский
Citations
9
Diabetes & Metabolic Syndrome Clinical Research & Reviews, Journal Year: 2024, Volume and Issue: 18(2), P. 102952 - 102952
Published: Feb. 1, 2024
Language: Английский
Citations
8
Annals of Internal Medicine, Journal Year: 2024, Volume and Issue: 177(5), P. 549 - 558
Published: April 19, 2024
Time-restricted eating (TRE) lowers body weight in many studies. Whether TRE induces loss independent of reductions calorie intake, as seen rodent studies, is unknown.
Language: Английский
Citations
8
Nutrients, Journal Year: 2025, Volume and Issue: 17(1), P. 169 - 169
Published: Jan. 2, 2025
Aims: To evaluate the effectiveness of a dual approach involving time-restricted eating (TRE) at different times day combined with physical activity (PA) on functional capacity and metabolic health in overweight or obese women. Methods: Random allocation sixty-one participants into four groups: early plus (ETRE-PA, n = 15, 31.8 ± 10.76 years, 89.68 13.40 kg, 33.5 5.53 kg/m2), late (LTRE-PA, 30.60 7.94 94.45 15.36 34.37 7.09 only (LTRE, 27.93 9.79 88.32 10.36 32.71 5.15 kg/m2) control group (CG, 36.25 11.52 89.01 11.68 33.66 6.18 kg/m2). The intervention lasted for 12 weeks all groups. Both ETRE-PA LTRE-PA groups engaged rigorous aerobic resistance-training program. Results: Significant reductions body weight mass index were observed compared to CG LTRE post-intervention (p < 0.0005). Only exhibited significant decrease fat 0.02), low-density lipoprotein cholesterol 0.01), aspartate aminotransferase 0.002). alanine levels 0.004) 0.02) These two latter achieved higher performances 6-min walking test, bench press, 30-s squat, crunch vertical jump 0.0005 both), leg extension 0.02 both) when Conclusion: integration TRE PA leads greater improvements composition, lipid profile, performance, no differences between approaches. This strategy offers promising solution
Language: Английский
Citations
1