Anodic
aluminum
oxide
(AAO)
films
have
a
wide
range
of
research
and
applications
in
the
field
nanoscience
technology.
Transparent
AAO
require
layer
to
be
peeled
off
from
substrate
which
it
is
attached,
involving
complex
preparation
process
immersion
variety
caustic
solutions,
resulting
prepared
that
are
very
prone
fragmentation
unfavorable
for
applications.
Here,
we
transparent
by
double-sided
anodization
method
with
secondary
anodization,
consists
porous
structure
spaced
barrier
layer.
These
can
bent
into
bow
shape
exhibit
good
toughness
under
action
external
forces
applied
at
both
ends.
Then,
were
subjected
thermal
shock
experiments,
changes
microstructure
before
after
analyzed.
The
relationship
between
they
was
also
investigated.
ACS Applied Materials & Interfaces,
Journal Year:
2024,
Volume and Issue:
16(30), P. 38989 - 39004
Published: July 22, 2024
Implant-associated
infections
and
excessive
immune
responses
are
two
major
postsurgical
issues
for
successful
implantation.
However,
conventional
strategies
including
antibiotic
treatment
inflammatory
regulation
always
compromised
due
to
the
comodification
of
various
biochemical
agents
instances
functional
interference.
It
is
imperative
provide
implant
surfaces
with
satisfactory
antibacterial
anti-inflammatory
properties.
Here,
a
dual-effect
nanostructured
polyetheretherketone
(PEEK)
surface
(NP@PDA/Zn)
bionic
mechano-bactericidal
nanopillars
immobilized
immunomodulatory
Zn2+
designed.
The
constructed
hybrid
display
remarkable
performance
against
Gram-negative
Gram-positive
strains
through
synergy
physical
chemical
bactericidal
effects
imposed
by
Zn2+.
Meanwhile,
immunoregulatory
property
evaluated
investigation
macrophage
polarization
both
in
vitro
vivo,
results
reveal
that
NP@PDA/Zn
could
downregulate
expression
M1-related
cytokines
decrease
M1
recruitment
lower
response.
Notably,
exhibited
exceptional
biocompatibility
discerning
biocidal
activity
between
bacterial
mammalian
cells
antioxidant
effectively
scavenges
ROS,
minimizing
potential
cytotoxicity.
Taken
together,
presents
convenient
promising
strategy
combining
synergistic
without
any
mutual
interference,
which
can
support
development
multifunctional
implant-associated
materials.
Nano Letters,
Journal Year:
2025,
Volume and Issue:
unknown
Published: March 15, 2025
Postcharging
antibacterials
have
shown
good
application
prospects
in
combating
bacterial
infections
through
electrical
interaction.
Herein,
manganese
oxide
nanosheets
situ
grown
on
carbon
fibers
(CM)
are
designed
to
perform
the
integration
of
mechanical
intervention
and
postcharging
therapy
for
efficient
killing.
This
electrode
disrupts
membranes
via
sharp-edged
microstructures.
After
charging
at
a
low
voltage
an
ultrashort
time,
charged
CM
affects
extracellular
electron
transfer
(EET)
bacteria
during
discharge
process
kill
bacteria.
Due
dual-antibacterial
mode,
after
−1
V
(vs
saturated
calomel
electrode,
SCE)
only
50.4
±
3
s,
lethality
rates
against
Escherichia
coli
Staphylococcus
aureus
within
0.5
h
both
exceed
98%.
Our
developed
ultrafast
negatively
exhibits
high
antibacterial
activity
cytotoxicity
fibroblast
cells,
providing
non-antibiotic
approach
combat
infection.
Nanomaterials,
Journal Year:
2023,
Volume and Issue:
13(20), P. 2799 - 2799
Published: Oct. 20, 2023
Bacterial
infections
and
antibiotic
resistance
remain
significant
contributors
to
morbidity
mortality
worldwide.
Despite
recent
advances
in
biomedical
research,
a
substantial
number
of
medical
devices
implants
continue
be
plagued
by
bacterial
colonisation,
resulting
severe
consequences,
including
fatalities.
The
development
nanostructured
surfaces
with
mechano-bactericidal
properties
has
emerged
as
promising
solution
this
problem.
These
employ
mechanical
rupturing
mechanism
lyse
cells,
effectively
halting
subsequent
biofilm
formation
on
various
materials
and,
ultimately,
thwarting
infections.
This
review
delves
into
the
prevailing
research
progress
within
realm
polymeric
surfaces.
It
also
investigates
diverse
fabrication
methods
for
developing
properties.
We
then
discuss
challenges
associated
each
approach
identify
gaps
that
warrant
exploration
future
studies,
emphasizing
potential
leverage
their
distinct
physical,
chemical,
over
traditional
like
metals.
Interdisciplinary Nursing Research,
Journal Year:
2024,
Volume and Issue:
3(2), P. 97 - 108
Published: May 6, 2024
Abstract
Nosocomial
infections,
as
the
most
common
adverse
event
in
health
care
environments,
have
become
an
urgent
global
challenge.
It
is
of
great
significance
solving
nosocomial
infections
to
improve
patient
survival
rates
and
reduce
economic
burden
on
patients.
Antibacterial
materials
play
a
crucial
role
prevention
treatment
infections.
Since
traditional
antibacterial
are
not
sufficient
satisfy
increasing
clinical
requirements,
advanced
widely
developed
biomedical
applications
hospital
fields,
aiming
at
achieving
more
efficient,
longer-lasting,
safer
antimicrobial
effects.
This
article
outlines
construction
strategies
mechanisms
materials,
including
bacterial
adhesion
prevention,
release
agents,
contact-kill
multistrategy-based
sterilization.
Meanwhile,
latest
progress
departments
public
environments
summarized
explored,
dressings,
medical
sutures,
implants,
bone
cements,
catheters,
plastics
products,
ceramics,
fiber
fabrics.
Finally,
challenges
future
directions
for
researches
translations
discussed,
providing
comprehensive
reference
guidance
development
system
applications.
