Polymers,
Journal Year:
2024,
Volume and Issue:
16(6), P. 794 - 794
Published: March 13, 2024
Probiotics
have
attracted
great
interest
from
many
researchers
due
to
their
beneficial
effects.
Encapsulation
of
probiotics
into
biopolymer
matrices
has
led
the
development
active
food
packaging
materials
as
an
alternative
traditional
ones
for
controlling
food-borne
microorganisms,
extending
shelf
life,
improving
safety,
and
achieving
health-promoting
The
challenges
low
survival
rates
during
processing,
storage,
delivery
gut
intestinal
colonization,
storage
stability,
controllability
greatly
limited
use
in
practical
food-preservation
applications.
encapsulation
with
a
protective
matrix
can
increase
resistance
harsh
environment
improve
rates,
making
appropriate
field.
Cellulose
extensive
attention
its
excellent
biocompatibility,
biodegradability,
environmental
friendliness,
renewability,
mechanical
strength.
In
this
review,
we
provide
brief
overview
main
types
cellulose
used
probiotic
encapsulation,
well
current
advances
different
encapsulating
strategies
cellulose,
grafted
cellulose-derived
materials,
including
electrospinning,
cross-linking,
in-situ
growth,
casting
strategies,
combinations.
effect
on
rate
patented
encapsulated
are
also
introduced.
addition,
applications
cellulose-encapsulated
industry
briefly
discussed.
Finally,
future
trends
toward
developing
improved
health
benefits
advanced
features
cellulose-based
Signal Transduction and Targeted Therapy,
Journal Year:
2024,
Volume and Issue:
9(1)
Published: Feb. 16, 2024
Abstract
The
human
gastrointestinal
tract
is
populated
with
a
diverse
microbial
community.
vast
genetic
and
metabolic
potential
of
the
gut
microbiome
underpins
its
ubiquity
in
nearly
every
aspect
biology,
including
health
maintenance,
development,
aging,
disease.
advent
new
sequencing
technologies
culture-independent
methods
has
allowed
researchers
to
move
beyond
correlative
studies
toward
mechanistic
explorations
shed
light
on
microbiome–host
interactions.
Evidence
unveiled
bidirectional
communication
between
central
nervous
system,
referred
as
“microbiota–gut–brain
axis”.
microbiota–gut–brain
axis
represents
an
important
regulator
glial
functions,
making
it
actionable
target
ameliorate
development
progression
neurodegenerative
diseases.
In
this
review,
we
discuss
mechanisms
As
provides
essential
cues
microglia,
astrocytes,
oligodendrocytes,
examine
communications
microbiota
these
cells
during
healthy
states
Subsequently,
diseases
using
metabolite-centric
approach,
while
also
examining
role
microbiota-related
neurotransmitters
hormones.
Next,
targeting
intestinal
barrier,
blood–brain
meninges,
peripheral
immune
system
counteract
dysfunction
neurodegeneration.
Finally,
conclude
by
assessing
pre-clinical
clinical
evidence
probiotics,
prebiotics,
fecal
transplantation
A
thorough
comprehension
will
foster
effective
therapeutic
interventions
for
management
Frontiers in Microbiology,
Journal Year:
2023,
Volume and Issue:
14
Published: Aug. 17, 2023
Probiotics,
like
lactic
acid
bacteria,
are
non-pathogenic
microbes
that
exert
health
benefits
to
the
host
when
administered
in
adequate
quantity.
Currently,
research
is
being
conducted
on
molecular
events
and
applications
of
probiotics.
The
suggested
mechanisms
by
which
probiotics
their
action
include;
competitive
exclusion
pathogens
for
adhesion
sites,
improvement
intestinal
mucosal
barrier,
gut
immunomodulation,
neurotransmitter
synthesis.
This
review
emphasizes
recent
advances
emerging
food
industry.
Due
capability
modulate
microbiota
attenuate
immune
system,
could
be
used
as
an
adjuvant
hypertension,
hypercholesterolemia,
cancer,
gastrointestinal
diseases.
Considering
functional
properties,
dairy,
beverage,
baking
industries.
After
developing
latest
techniques
researchers,
can
now
survive
within
harsh
processing
conditions
withstand
GI
stresses
quite
effectively.
Thus,
potential
efficiently
utilized
a
commercial
scale
Applied Food Research,
Journal Year:
2022,
Volume and Issue:
3(1), P. 100248 - 100248
Published: Dec. 19, 2022
Consumer
interest
in
probiotics
is
significantly
growing
due
to
their
positive
impact
on
health.
Dairy
products
are
common
and
most
preferred
"delivery
vehicle"
the
food
industry.
However,
dairy
associated
with
increased
risk
people,
lactose
intolerance,
galactosemia,
allergy
milk
proteins,
high
cholesterol
levels.
For
such
cases,
non-dairy
based
probiotic
foods
could
offer
a
good
alternative.
Among
foods,
fruit
juice
more
dietary
inclusive,
convenient,
well
accepted
by
all
age
groups.
Therefore,
be
used
as
suitable
carrier
delivery.
Lactobacillus
Bifidobacterium
two
main
strains
commercially
worldwide
for
preparing
proven
health
benefits.
protecting
cells
key
formulation
order
guarantee
survival.
various
encapsulation
techniques,
cell
viability,
materials
downstream
processing
utilization
discussed
review.
different
spray
drying
emerged
an
alternative
technique
better
of
juices
possibilities
industrial
applications
cost-effective
continuous
process.
considered
efficient
industry
probiotification.
Nanomaterials,
Journal Year:
2023,
Volume and Issue:
13(15), P. 2185 - 2185
Published: July 27, 2023
Probiotics
have
garnered
significant
attention
in
recent
years
due
to
their
potential
advantages
diverse
biomedical
applications,
such
as
acting
antimicrobial
agents,
aiding
tissue
repair,
and
treating
diseases.
These
live
bacteria
must
exist
appropriate
quantities
precise
locations
exert
beneficial
effects.
However,
viability
activity
can
be
significantly
impacted
by
the
surrounding
tissue,
posing
a
challenge
maintain
stability
target
location
for
an
extended
duration.
To
counter
this,
researchers
formulated
various
strategies
that
enhance
of
probiotics
encapsulating
them
within
biomaterials.
This
approach
enables
site-specific
release,
overcoming
technical
impediments
encountered
during
processing
application
probiotics.
A
range
materials
utilized
probiotics,
several
methods
employed
this
encapsulation
process.
article
reviews
advancements
encapsulated
biomaterials,
examining
materials,
methods,
effects
encapsulation.
It
also
provides
overview
hurdles
faced
currently
available
biomaterial-based
probiotic
capsules
suggests
future
research
directions
field.
Despite
progress
achieved
date,
numerous
challenges
persist,
necessity
developing
efficient,
reproducible
Furthermore,
there
is
need
design
more
robust
targeted
delivery
vehicles.
Advanced Materials,
Journal Year:
2024,
Volume and Issue:
36(32)
Published: Jan. 21, 2024
Probiotics
with
diverse
and
crucial
properties
functions
have
attracted
broad
interest
from
many
researchers,
who
adopt
intestinal
delivery
of
probiotics
to
modulate
the
gut
microbiota.
However,
major
problems
faced
for
therapeutic
applications
are
viability
colonization
during
their
processing,
oral
intake,
subsequent
gut.
The
challenges
simple
(stability,
controllability,
targeting,
etc.)
greatly
limited
use
in
clinical
therapies.
Nanotechnology
can
endow
be
delivered
intestine
improved
survival
rate
increased
resistance
adverse
environment.
Additionally,
progress
synthetic
biology
has
created
new
opportunities
efficiently
purposefully
designing
manipulating
probiotics.
In
this
article,
a
brief
overview
types
delivery,
current
different
probiotic
encapsulation
strategies,
including
chemical,
physical,
genetic
strategies
combinations,
emerging
single-cell
using
nanocoating
methods,
is
presented.
action
mechanisms
that
responsible
eliciting
beneficial
effects
also
briefly
discussed.
Finally,
engineered
discussed,
future
trends
toward
developing
advanced
features
health
benefits
proposed.
Nutrients,
Journal Year:
2024,
Volume and Issue:
16(5), P. 636 - 636
Published: Feb. 25, 2024
Nanotechnology
in
human
nutrition
represents
an
innovative
advance
increasing
the
bioavailability
and
efficiency
of
bioactive
compounds.
This
work
delves
into
multifaceted
dietary
contributions
nanoparticles
(NPs)
their
utilization
for
improving
nutrient
absorption
ensuring
food
safety.
NPs
exhibit
exceptional
solubility,
a
significant
surface-to-volume
ratio,
diameters
ranging
from
1
to
100
nm,
rendering
them
invaluable
applications
such
as
tissue
engineering
drug
delivery,
well
elevating
quality.
The
encapsulation
vitamins,
minerals,
antioxidants
within
introduces
approach
counteract
nutritional
instabilities
low
promoting
health.
Nanoencapsulation
methods
have
included
production
nanocomposites,
nanofibers,
nanoemulsions
benefit
delivery
Nutrition-based
nanotechnology
nanoceuticals
are
examined
economic
viability
potential
increase
absorption.
Although
advancement
demonstrates
promising
results,
some
limitations
concerns
related
safety
regulation
need
be
widely
discussed
future
research.
Thus,
could
open
new
paths
advances
food,
benefiting
nutrition.
International Journal of Molecular Sciences,
Journal Year:
2024,
Volume and Issue:
25(11), P. 5842 - 5842
Published: May 27, 2024
This
study
provides
a
brief
discussion
of
the
major
nanopharmaceuticals
formulations
as
well
impact
nanotechnology
on
future
pharmaceuticals.
Effective
and
eco-friendly
strategies
biofabrication
are
also
highlighted.
Modern
approaches
to
designing
pharmaceutical
nanoformulations
(e.g.,
3D
printing,
Phyto-Nanotechnology,
Biomimetics/Bioinspiration,
etc.)
outlined.
paper
discusses
need
use
natural
resources
for
“green”
design
new
with
therapeutic
efficiency.
Nanopharmaceuticals
research
is
still
in
its
early
stages,
preparation
nanomaterials
must
be
carefully
considered.
Therefore,
safety
long-term
effects
not
overlooked.
The
testing
represents
an
essential
point
their
further
applications.
Vegetal
scaffolds
obtained
by
decellularizing
plant
leaves
represent
valuable,
bioinspired
model
nanopharmaceutical
that
avoids
using
animals.
Nanoformulations
critical
various
fields,
especially
pharmacy,
medicine,
agriculture,
material
science,
due
unique
properties
advantages
over
conventional
allows
improved
solubility,
bioavailability,
targeted
drug
delivery,
controlled
release,
reduced
toxicity.
have
transitioned
from
experimental
stages
being
vital
component
clinical
practice,
significantly
improving
outcomes
medical
fields
cancer
treatment,
infectious
diseases,
neurological
disorders,
personalized
advanced
diagnostics.
Here
key
points
highlighting
importance.
significant
challenges,
opportunities,
directions
mentioned
final
section.
Nano Letters,
Journal Year:
2024,
Volume and Issue:
24(4), P. 1081 - 1089
Published: Jan. 16, 2024
Oral
administration
of
probiotics
orchestrates
the
balance
between
intestinal
microbes
and
immune
response.
However,
effective
delivery
in
situ
colonization
are
limited
by
harsh
environment
gastrointestinal
tract.
Herein,
we
provide
a
microfluidics-derived
encapsulation
strategy
to
address
this
problem.
A
novel
synergistic
system
composed
EcN
Nissle
1917
prebiotics,
including
alginate
sodium
inulin
gel,
for
treating
inflammatory
bowel
disease
colitis-associated
colorectal
cancer
is
proposed.
We
demonstrated
that
EcN@AN
microparticles
yielded
promising
resistance
on-demand
probiotic
colon-retentive
capability.
efficiently
ameliorated
inflammation
modulated
gut
microbiome
experimental
colitis.
Moreover,
prebiotic
composition
enhanced
fermentation
relative
short-chain
fatty
acid
metabolites,
kind
postbiotics,
exert
anti-inflammatory
tumor-suppressive
effects
murine
models.
This
microfluidcis-based
approach
coordinated
prebiotics
may
have
broad
implications
bacteriotherapy
applications.
