Bacterial cellulose-based composites as vehicles for dermal and transdermal drug delivery: A review DOI
Sajad Mohammadi,

Farzaneh Jabbari,

Valiollah Babaeipour

et al.

International Journal of Biological Macromolecules, Journal Year: 2023, Volume and Issue: 242, P. 124955 - 124955

Published: May 26, 2023

Language: Английский

Adsorption of heavy metals from wastewater by chitosan: A review DOI Creative Commons
Ali Basem, Dheyaa J. Jasim, Hasan Sh. Majdi

et al.

Results in Engineering, Journal Year: 2024, Volume and Issue: 23, P. 102404 - 102404

Published: June 14, 2024

With the progress of human civilization, development technology and increasing population, world is currently facing an important problem called pollution, which threatens lives inhabitants planet, so that in every country, environmental protection a serious concern statesmen. Pollution caused by accumulation soil water from persistent toxic compounds such as chemicals, salts, heavy metals radioactive substances are causes diseases have inconsistent effects on growth health animals humans. The release environment due to industrialization expansion urbanization has brought great problems all over world, increase pollution concerns their carcinogenic properties, indestructibility biological accumulation. Adsorption industrial effluents one issues. So far, various methods been considered for adsorption these metals, use methods. There natural synthetic adsorption, each specific advantages, recently chitosan also composites used. Being economical terms economy, easy access compliance with standards among advantages method. In this study, basis performance, disadvantages different finally adsorbent nanofibers discussed.

Language: Английский

Citations

34

Polysaccharide mediated nanodrug delivery: A review DOI
Dinanath Gaikwad,

Ravina D Sutar,

Dhanashri Patil

et al.

International Journal of Biological Macromolecules, Journal Year: 2024, Volume and Issue: 261, P. 129547 - 129547

Published: Jan. 25, 2024

Language: Английский

Citations

25

Carbohydrate polymers based MnO2 nanostructures for catalytic and antibacterial activity; kinetic modeling and molecular docking analysis DOI
Muhammad Ikram, Sawaira Moeen, Anum Shahzadi

et al.

Materials Science in Semiconductor Processing, Journal Year: 2024, Volume and Issue: 181, P. 108633 - 108633

Published: June 24, 2024

Language: Английский

Citations

23

Advances in chitosan-based blends as potential drug delivery systems: A review DOI
Mohamed J. Saadh, Chou‐Yi Hsu, Mohammed Ahmed Mustafa

et al.

International Journal of Biological Macromolecules, Journal Year: 2024, Volume and Issue: 273, P. 132916 - 132916

Published: June 5, 2024

Language: Английский

Citations

19

Biogenic selenium nanoparticles and selenium/chitosan-Nanoconjugate biosynthesized by Streptomyces parvulus MAR4 with antimicrobial and anticancer potential DOI Creative Commons
Mervat G. Hassan,

Mariam T. Hawwa,

Dina M. Baraka

et al.

BMC Microbiology, Journal Year: 2024, Volume and Issue: 24(1)

Published: Jan. 12, 2024

Abstract Background As antibiotics and chemotherapeutics are no longer as efficient they once were, multidrug resistant (MDR) pathogens cancer presently considered two of the most dangerous threats to human life. In this study, Selenium nanoparticles (SeNPs) biosynthesized by Streptomyces parvulus MAR4, nano-chitosan (NCh), their nanoconjugate (Se/Ch-nanoconjugate) were suggested be efficacious antimicrobial anticancer agents. Results SeNPs MAR4 NCh successfully achieved conjugated. The spherical with a mean diameter 94.2 nm high stability. Yet, Se/Ch-nanoconjugate was semispherical 74.9 much higher SeNPs, NCh, showed significant activity against various microbial strong inhibitory effect on tested metabolic key enzymes [phosphoglucose isomerase (PGI), pyruvate dehydrogenase (PDH), glucose-6-phosphate (G6PDH) nitrate reductase (NR)]; powerful agent. Furthermore, revealed cytotoxicity HepG2 (IC 50 = 13.04 μg/ml) moderate toxicity Caki-1 (HTB-46) tumor cell lines 21.35 but low WI-38 normal line 85.69 μg/ml). Nevertheless, displayed substantial IC values 11.82 7.83 μg/ml, respectively. Consequently, may more easily absorbed both lines. However, it exhibited very 153.3 μg/ml. Therefore, presented activity. Conclusion convincingly recommended used in biomedical applications versatile potent agents ensuring notable levels biosafety, environmental compatibility, efficacy.

Language: Английский

Citations

18

Chitosan-Based Scaffolds Incorporated with Silver Nanoparticles for the Treatment of Infected Wounds DOI Creative Commons
Sibusiso Alven, Blessing A. Aderibigbe

Pharmaceutics, Journal Year: 2024, Volume and Issue: 16(3), P. 327 - 327

Published: Feb. 26, 2024

Bacterial infections are major problems in wound care due to their impact on the retarded process of healing, leading chronic wounds. Most presently utilized dressing products exhibit poor antimicrobial properties. Wound dressings formulated from chitosan have been reported be effective for treating infected wounds, resulting antibacterial properties chitosan. The chitosan-based can further enhanced by incorporating metallic nanoparticles into them, such as silver, zinc, titanium, etc. incorporation silver has widely explored design dressings. promotes accelerated wound-healing processes activity. healing these metal-based is via regulation re-epithelialization and inflammation without affecting viability normal cells. However, there few reports that evaluate infectious animal models prove efficacy. vivo toxicity still needs addressed, revealing need preclinical clinical trials. fabrication incorporated with not fully explored, especially wounds requiring immediate treatment. possible interactions between scaffolds result synergistic effects understood studied. This review provides a comprehensive report outcomes materials loaded managing

Language: Английский

Citations

18

Chitosan: A sustainable biobased material for diverse applications DOI

Azuka Nwabike Amitaye,

Elias E. Elemike,

Honesty Bamidele Akpeji

et al.

Journal of environmental chemical engineering, Journal Year: 2024, Volume and Issue: 12(4), P. 113208 - 113208

Published: June 1, 2024

Language: Английский

Citations

16

Adsorption of emerging pollutants utilizing chitosan derivatives: Recent advances and future perspective DOI
Prabhat Kumar Patel,

Ramagopal V.S. Uppaluri

International Journal of Biological Macromolecules, Journal Year: 2025, Volume and Issue: 299, P. 140203 - 140203

Published: Jan. 21, 2025

Language: Английский

Citations

2

A Review on Biomedical Application of Polysaccharide-Based Hydrogels with a Focus on Drug Delivery Systems DOI Open Access
Bahareh Farasati Far, Mohammad Reza Naimi‐Jamal,

Maryam Safaei

et al.

Polymers, Journal Year: 2022, Volume and Issue: 14(24), P. 5432 - 5432

Published: Dec. 12, 2022

Over the last years of research on drug delivery systems (DDSs), natural polymer-based hydrogels have shown many scientific advances due to their intrinsic properties and a wide variety potential applications. While efficacy cytotoxicity play key role, adopting proper DDS is crucial preserve along route administration possess desired therapeutic effect at targeted site. Thus, technology can be used overcome difficulties maintaining drugs physiologically related serum concentration for prolonged periods. Due outstanding biocompatibility, polysaccharides been thoroughly researched as biological material advancement. To formulate modified DDS, cross-link with different molecules, resulting in hydrogels. According our recent findings, certain spot occurs external stimulation such temperature, pH, glucose, or light. As an adjustable biomedical device, hydrogel has tremendous nanotech applications involved health areas pharmaceutical engineering. An overview characteristics functionalities provided this review. We focus discussing various kinds hydrogel-based effectively delivering that are made polysaccharides.

Language: Английский

Citations

62

Carbohydrate polymer-based nanocomposites for breast cancer treatment DOI
Farnaz Dabbagh Moghaddam, Golnaz Heidari, Ehsan Nazarzadeh Zare‬

et al.

Carbohydrate Polymers, Journal Year: 2022, Volume and Issue: 304, P. 120510 - 120510

Published: Dec. 29, 2022

Language: Английский

Citations

40