International Journal of Biological Macromolecules, Journal Year: 2024, Volume and Issue: unknown, P. 139082 - 139082
Published: Dec. 1, 2024
Language: Английский
Food Science and Biotechnology, Journal Year: 2025, Volume and Issue: 34(9), P. 1819 - 1834
Published: Jan. 6, 2025
Language: Английский
Citations
1
Discover Nano, Journal Year: 2025, Volume and Issue: 20(1)
Published: Jan. 14, 2025
Multifunctional membranes applied to biomedical materials become attractive support the biological agents and increase their properties. In this study, biopolymeric fibers based on polycaprolactone (PCL) pectin (PEC) were reinforced with faujasite zeolite (FAU) for cloxacillin antibiotic (CLX) loading. FAU a high specific surface area (347 ± 8 m2 g-1), crystallinity particles diameter of up 100 nm produced under optimized synthesis conditions (100 °C/4 h). Zeolites incorporated into polymeric nanofibers be carrier in wound treatment, using electrospinning as an efficient method. The showed good mechanical resistance incorporation CLX was proven by assays inhibit growth Staphylococcus aureus bacteria. controlled release different pH conditions, which simulate environment, carried out 229 h, achieving released concentration 6.18 0.02 mg L-1. These results prove that obtaining hybrid fiber (polymer-zeolite) incorporate drugs manner successfully achieved. bactericidal activity material shows its use measured applications could alternative conventional methods.
Language: Английский
Citations
1
Food Frontiers, Journal Year: 2024, Volume and Issue: unknown
Published: Sept. 25, 2024
Abstract Polysaccharides, also known as glycans, are biological macromolecules consisting of many monosaccharide units. Alongside proteins, nucleic acids, and lipids, they constitute the four fundamental substances crucial for life activities essential growth development living organisms. As natural products with inherent activity, polysaccharides widely available, nontoxic, possess numerous functional properties, holding immense potential advancement in food, medicine, cosmetics. Furthermore, exploration polysaccharide‐based drugs, an alternative to conventional therapies, emerges a promising avenue addressing future disease challenges. This article comprehensively reviews sources, structural characteristics, synthesis, degradation, functions, applications polysaccharides. The pharmacological applications, antitumor, antiaging, antioxidant, hypoglycemic, anti‐inflammatory, antiviral, anticoagulant is summarized. Additionally, role environmental protection discussed. It anticipated that this review will offer innovative strategic insights, serving theoretical foundation inspiration subsequent research on healthcare.
Language: Английский
Citations
8
Artificial Cells Nanomedicine and Biotechnology, Journal Year: 2024, Volume and Issue: 52(1), P. 564 - 586
Published: Dec. 5, 2024
Cancer has a high rate of incidence and mortality throughout the world. Although several conventional approaches have been developed for treatment cancer, such as surgery, chemotherapy, radiotherapy thermal therapy, they remarkable disadvantages which result in inefficient cancer. For example, immunogenicity, prolonged treatment, non-specificity, metastasis cost are considered major drawbacks chemotherapy. Therefore, there is fundamental requirement development breakthrough technologies cancer suppression. Polysaccharide-based drug delivery systems (DDSs) most reliable carriers therapy. Polysaccharides, kind practical biomaterials, divided into types, including chitosan, alginates, dextran, hyaluronic acid, cyclodextrin, pectin, etc. Polysaccharides extracted from different natural resources (like herbal, marine, microorganisms, etc.). The potential features polysaccharides made them candidates therapeutics to sites; simple purification, ease modification functionalization, hydrophilicity, serum stability, appropriate loading capacity, biocompatibility, bioavailability, biodegradability stimuli-responsive sustained release manner considerable aspects these biopolymers. This review highlights applications polysaccharides-based DDSs pharmaceutical science
Language: Английский
Citations
7
ACS Omega, Journal Year: 2024, Volume and Issue: 9(40), P. 41107 - 41129
Published: Sept. 16, 2024
This review examines the convergence of silver nanoparticles (AgNPs), three-dimensional (3D) printing, and wound healing, focusing on significant advancements in these fields. We explore unique properties AgNPs, notably their strong antibacterial efficacy potential applications enhancing recovery. Furthermore, delves into 3D printing technology, discussing its core principles, various materials employed, recent innovations. The integration AgNPs 3D-printed structures for regenerative medicine is analyzed, emphasizing benefits this combined approach identifying challenges that must be addressed. comprehensive overview aims to elucidate current state field direct future research toward developing more effective solutions healing.
Language: Английский
Citations
6
International Journal of Biological Macromolecules, Journal Year: 2024, Volume and Issue: 282, P. 137209 - 137209
Published: Nov. 4, 2024
Language: Английский
Citations
5
Current Pharmaceutical Design, Journal Year: 2024, Volume and Issue: 31(4), P. 244 - 260
Published: April 30, 2024
In recent years, advancements in chemistry have allowed the tailoring of materials at nanoscopic level as needed. There are mainly four main types nanomaterials used drug carriers:metal-based nanomaterials, organic inorganic and polymer nanomaterials. The a carrier showed advantages for decreased side effects with higher therapeutic index. stability compounds increased by encapsulation within nano-drug carriers, leading to systemic toxicity. Nano-drug carriers also controlled release system-made solubility characteristics nanoparticles surface coating surfactants. review focuses on different nanoparticle synthesis process, techniques purposes, applications prospects biomedical applications.
Language: Английский
Citations
4
Fitoterapia, Journal Year: 2025, Volume and Issue: 181, P. 106379 - 106379
Published: Jan. 6, 2025
Language: Английский
Citations
0
RSC Advances, Journal Year: 2025, Volume and Issue: 15(10), P. 7926 - 7937
Published: Jan. 1, 2025
Alginate nanoparticles (ALG-NPs) were synthesized in reverse micelles (RMs) as nanoreactors, exploring the role of interfacial charge on their structure, size, and encapsulation properties.
Language: Английский
Citations
0
Food Science & Nutrition, Journal Year: 2025, Volume and Issue: 13(3)
Published: March 1, 2025
ABSTRACT This study addresses the challenge of stabilizing vitamin D 3 , an unstable, fat‐soluble vitamin, whose efficacy is diminished by environmental factors. The objective was to encapsulate using pectin (1%–3% w/w) and whey protein concentrate (WPC) (1%–2% at varying ratios, facilitated Tween 80 surfactant (0.5% 2.5% w/w), through high‐pressure homogenization create oil‐in‐water (O/W) nanoemulsions. Optimization preparation conditions for both aqueous oil phases conducted experimental design. Characterization stability nanoemulsions were assessed scanning electron microscopy (SEM), dynamic light scattering (DLS), Fourier transform infrared spectroscopy (FTIR). Release kinetics vitamin‐D into sunflower monitored high‐performance liquid chromatography (HPLC) under various conditions. optimal encapsulation achieved with a 30:70 oil‐to‐aqueous phase ratio, comprising 27.5% in phase, 1% WPC 2% phase. nanoemulsion demonstrated over 60 days storage, z ‐average particle size 98.2 nm. HPLC analysis indicated 90% recovery encapsulated oil. These findings suggest promising approach developed enhancing bioavailability shelf life food applications.
Language: Английский
Citations
0