Synergistic applications of cyclodextrin-based systems and metal–organic frameworks in transdermal drug delivery for skin cancer therapy

Journal of Materials Chemistry B, Journal Year: 2024, Volume and Issue: 12(16), P. 3807 - 3839

Published: Jan. 1, 2024

This review article explores the innovative field of eco-friendly cyclodextrin-based coordination polymers and metal-organic frameworks (MOFs) for transdermal drug delivery in case skin cancer therapy. We critically examine significant advancements developing these nanocarriers, with a focus on their unique properties such as biocompatibility, targeted release, enhanced permeability. These attributes are instrumental addressing limitations inherent traditional treatments represent paradigm shift towards more effective patient-friendly therapeutic approaches. Furthermore, we discuss challenges faced optimizing synthesis process large-scale production while ensuring environmental sustainability. The also emphasizes immense potential clinical applications nanocarriers therapy, highlighting role facilitating targeted, controlled release which minimizes systemic side effects. Future could see being customized to individual patient profiles, potentially revolutionizing personalized medicine oncology. With further research trials, hold promise transforming landscape treatment. this study, aim provide comprehensive overview current state outline future directions advancing development application nanocarriers.

Language: Английский

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State-of-All-the-Art and Prospective Hydrogel-Based Transdermal Drug Delivery Systems

Applied Sciences, Journal Year: 2024, Volume and Issue: 14(7), P. 2926 - 2926

Published: March 30, 2024

Over the past few decades, notable advancements have been made in field of transdermal drug delivery systems (TDDSs), presenting a promising alternative to conventional oral administration. This comprehensive review aims enhance understanding this method by examining various techniques, skin’s role as barrier TDDS, factors affecting skin diffusion, and current challenges TDDSs. The primary focus analysis centers on TDDSs utilizing hydrogels. A thorough exploration hydrogel fundamentals, encompassing structure, properties, synthesis, is provided underscore importance hydrogels carriers delivery. concluding section delves into strategies for hydrogel-based delivery, addressing exploring future directions.

Language: Английский

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Statistical design and optimization of nano-transfersomes based chitosan gel for transdermal delivery of cefepime

Drug Development and Industrial Pharmacy, Journal Year: 2024, Volume and Issue: 50(6), P. 511 - 523

Published: May 8, 2024

Objectives: This research aimed to overcome challenges posed by cefepime excessive elimination rate and poor patient compliance developing transdermal delivery system using nano-transfersomes based chitosan gel.

Language: Английский

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Recent progress of microneedles in transdermal immunotherapy: A review

International Journal of Pharmaceutics, Journal Year: 2024, Volume and Issue: 662, P. 124481 - 124481

Published: July 23, 2024

Language: Английский

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Dissolving microneedle synergistic rocaglamide-loaded liposome to regulate abnormal neutrophils for anti-psoriasis

International Journal of Pharmaceutics, Journal Year: 2025, Volume and Issue: 670, P. 125180 - 125180

Published: Jan. 5, 2025

Language: Английский

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