Editorial: Advanced three-dimensional platforms for tissue regeneration: when the microenvironment matters DOI Creative Commons
Enrico Domenico Lemma, Antonella Motta, Alessio Bucciarelli

et al.

Frontiers in Bioengineering and Biotechnology, Journal Year: 2023, Volume and Issue: 11

Published: Aug. 9, 2023

EDITORIAL article Front. Bioeng. Biotechnol., 09 August 2023Sec. Biomaterials Volume 11 - 2023 | https://doi.org/10.3389/fbioe.2023.1265642

Language: Английский

3D printing of stimuli-responsive hydrogel materials: Literature review and emerging applications DOI Creative Commons
Zia Ullah Arif, Muhammad Yasir Khalid, Ali Tariq

et al.

Giant, Journal Year: 2023, Volume and Issue: 17, P. 100209 - 100209

Published: Nov. 15, 2023

Additive manufacturing (AM) aka three-dimensional (3D) printing has been a well-established and unparalleled technology, which is expanding the boundaries of materials science exhibiting an enormous potential to fabricate intricate geometries for healthcare, electronics, construction sectors. In contemporary era, combination AM technology stimuli-responsive hydrogels (SRHs) helps create dynamic functional structures with extreme accuracy, are capable changing their shape, functional, or mechanical properties in response environmental cues such as humidity, heat, light, pH, magnetic field, electric etc. 3D SRHs permits creation on-demand dynamically controllable shapes excellent control over various self-repair, self-assembly, multi-functionality, These accelerate researchers think unthinkable applications. Additively manufactured objects have shown applications like tissue engineering, drug delivery, soft robots, sensors, other biomedical devices. The current review provides recent progress SRHs, more focus on techniques, stimuli mechanisms, shape morphing behaviors, Finally, trends future roadmap additively smart different also presented, will be helpful research. This holds great promise providing fundamental knowledge about diverse

Language: Английский

Citations

71

Fish Collagen Cross‐Linking Strategies to Improve Mechanical and Bioactive Capabilities for Tissue Engineering and Regenerative Medicine DOI Creative Commons

Alexandria R. Leonard,

Mathew Cumming, Azam Ali

et al.

Advanced Functional Materials, Journal Year: 2024, Volume and Issue: 34(45)

Published: July 31, 2024

Abstract Collagen is the most abundant protein found in humans and fundamental to tissue structure function. products used biomedical research are primarily derived from mammals, despite being mainly responsible for providing strength native connective tissue, collagen hydrogels have comparatively low mechanical properties without use of additional cross‐linking strategies. Alternative sources collagen, like fish emerging as key biomaterials engineering regenerative medicine (TERM). By addressing cultural/religious concerns, ease extraction, absence mammalian‐derived allergens, retention functional motifs, has many promising characteristics that make it a suitable alternative mammalian collagen. Several physical chemical strategies explored create more stable resilient scaffolds variety TERM applications. This comprehensive review explores how these modifications optimized hydrogel systems. Herein, their reported research, well types treatments (including sterilization) alter structures functions, presented date.

Language: Английский

Citations

8

4D Printing of Physical Stimuli-Responsive Hydrogels for Localized Drug Delivery and Tissue Engineering DOI

Alireza Sadraei,

Seyed Morteza Naghib

Polymer Reviews, Journal Year: 2024, Volume and Issue: unknown, P. 1 - 65

Published: Nov. 20, 2024

The biomedical industry has witnessed a transformative evolution with the advent of 3D printing technology. However, inherent limitations, such as inability to produce dynamic human tissues due absence temporal dimension, have persisted, resulting in static and inanimate printed products. To address this challenge enable creation living constructs, concept 4D emerged, marking paradigm shift additive manufacturing. In printing, time becomes fourth breathing life into previously creations. This review paper explores journey from pivotal role manufacturing process. Specifically, it highlights integration time-dependent responsive materials, focusing on stimuli-responsive hydrogels, cornerstone advancements. These materials exhibit remarkable ability adapt respond various stimuli, encompassing physical, chemical, biological signals. delves recent publications synergy between these stimuli shedding light their intricate interactions potential applications. One primary areas interest lies medical applications, notably tissue engineering, where holds immense promise. utilization creating biomimetic scaffolds that can dynamically complex environments. Furthermore, discusses technical considerations prospects technology, emphasizing its revolutionize landscape. amalgamation opens new avenues for personalized medicine, localized drug delivery, regenerative therapies, bridging gap requirements modern healthcare. present offers complete examination evolution, challenges, paving way innovations field.

Language: Английский

Citations

6

Recent advances in three-dimensional printing in cardiovascular devices: Bench and bedside applications DOI Creative Commons

Yihong Shen,

Jie Cui, Yu Xiao

et al.

Smart Materials in Medicine, Journal Year: 2023, Volume and Issue: 5(1), P. 36 - 51

Published: July 17, 2023

Three-dimensional (3D) printing is emerging as an innovative technology, which widely used in cardiovascular disease at bench and bedside. During the last decade, with development of 3D industry, many printed models have been clinic, because it can provide advantage haptic feedback, direct manipulation, enhanced doctors' understanding anatomy underlying pathologies. In addition to preparation models, technology also shows great application potential regenerative medicine has advantages integrating cells, cytokines materials. Although still a gap between bedside, this gradually narrowing new materials recently. review, we firstly analyze characteristics clinical needs diseases, introduce concept category technology. Secondly, summarize stents, vascular graft, network, heart organs end, discuss challenges future perspectives diseases.

Language: Английский

Citations

15

Organ bioprinting: progress, challenges and outlook DOI
Yang Wu,

Minghao Qin,

Xue Yang

et al.

Journal of Materials Chemistry B, Journal Year: 2023, Volume and Issue: 11(43), P. 10263 - 10287

Published: Jan. 1, 2023

Bioprinting, as a groundbreaking technology, enables the fabrication of biomimetic tissues and organs with highly complex structures, multiple cell types, mechanical heterogeneity, diverse functional gradients. With growing demand for organ transplantation limited number donors, bioprinting holds great promise addressing shortage by manufacturing completely organs. While complete remains distant goal, there has been considerable progress in development bioprinted transplantable regenerative medicine. This review article recapitulates current achievements 3D bioprinting, primarily encompassing five important human body (i.e., heart, kidneys, liver, pancreas, lungs). Challenges from cellular techniques, biomanufacturing technologies, maturation techniques are also deliberated broad application bioprinting. In addition, integration other cutting-edge technologies including machine learning, organoids, microfluidics is envisioned, which strives to offer reader prospect constructing

Language: Английский

Citations

11

Biopolymer-chitin products by direct ink writing (DIW): A review DOI Creative Commons

Varsha Antanitta S,

Jigar Patadiya, Balasubramanian Kandasubramanian

et al.

Hybrid Advances, Journal Year: 2023, Volume and Issue: 5, P. 100115 - 100115

Published: Dec. 1, 2023

The role of chitin has been focused in the domain biochemistry, materials science, medicine, and environmental science due to its non-toxicity, biodegradability, thermostability, biocompatibility. projection period between 2023 2033 is predicted have a significant Compounded Annual Growth Rate (CAGR) 12.3 % worldwide market according reports, Young's modulus crystals 150 GPa, which comparable cellulose (134 GPa). In comparison other fabrication techniques like electrospinning solvent casting, DIW method more effective for producing complex 3D geometries. flexible technique that covers range substances, such as natural polymers (carrageenan, cellulose, silk, chitin), synthetic (polyurethane, polyvinylalcohol, acrylonitrile butadiene styrene), ceramics composites form ink. present review provides an insight into based products by approach introduces key essential acquaintance biopolymer-based ink creation variety forms, including nanofibers, whiskers, followed polymer stripes patterned on films with ability transform intricate multidimensional architectures using process, also highlighted crucial critical understanding utilization engineering bone tissue, shape-morphing film, skin bearing architecture their possible future abundance industries.

Language: Английский

Citations

11

Application of 3D Printing Technology in Dentistry: A Review DOI Open Access

Yangqing Chen,

Junchao Wei

Polymers, Journal Year: 2025, Volume and Issue: 17(7), P. 886 - 886

Published: March 26, 2025

Three-dimensional (3D) printing is a cutting-edge technology that widely used in biomedical fields to construct various commercial products or scaffolds for theoretical research. In this review, 3D technologies with different principles are briefly introduced, including selective laser melting (SLM), sintering (SLS), fused deposition modeling (FDM), stereolithography (SLA), and digital light processing (DLP). addition, the applications of dentistry, such as dental implantology, prosthodontics, orthodontics, maxillofacial surgery, tissue regeneration, were summarized. Furthermore, perspective challenges also addressed help readers obtain clear map development dentistry.

Language: Английский

Citations

0

AI tool for prediction of ECM mimics hydrogel formulations via click chemistry DOI
Francesca Cadamuro, Marco Piazzoni,

Elia Gamba

et al.

Biomaterials Advances, Journal Year: 2025, Volume and Issue: unknown, P. 214323 - 214323

Published: April 1, 2025

Language: Английский

Citations

0

3D Digital Light Process Bioprinting: Cutting-Edge Platforms for Resolution of Organ Fabrication DOI Creative Commons

Yun Geun Jeong,

James J. Yoo, Sang Jin Lee

et al.

Materials Today Bio, Journal Year: 2024, Volume and Issue: 29, P. 101284 - 101284

Published: Oct. 2, 2024

Language: Английский

Citations

3

Plasma-Treated Collagen Functionalized With Chondroitin Sulfate as Bioactive and Nanostructured Extracellular Matrix Mimics DOI Creative Commons
Federica Barbugian, Francesca Cadamuro, Francesco Nicotra

et al.

Nanomedicine, Journal Year: 2024, Volume and Issue: 19(9), P. 799 - 810

Published: Feb. 22, 2024

Cell microenvironment contains a plethora of information that influences cell modulation. Indeed, the extracellular matrix plays central role in tissue development. Reproducing cell-extracellular crosstalk able to recapitulate both physical and biochemical signals is crucial obtain functional models or regenerative strategies.

Language: Английский

Citations

2