Foods,
Journal Year:
2025,
Volume and Issue:
14(6), P. 998 - 998
Published: March 14, 2025
The
significant
demand
for
medicinal
plants
with
special
efficacy
has
prompted
us
to
adopt
appropriate
processing
methods
enhance
the
nutritional
quality
and
flavor
of
raw
materials.
This
study
evaluated
impacts
freeze-drying
(FD),
hot-air
drying
(HAD),
spray
(SD)
on
bioactive
compounds,
characteristics,
inhibition
starch
digestion
in
mulberry
leaf
ethanol
extract
(MLE).
Results
indicated
that
FDMLE
exhibited
highest
total
alkaloids
content
(TAC:
0.14
±
0.02
mg/g)
flavonoid
(TFC:
19.32
0.58
mg/g),
along
inhibitory
effects
hydrolysis
at
180
min
(starch
rate
<50%).
microstructure
HADMLE
was
closest
powder
(ML),
but
SD
better
preserved
color
ML
(ΔE
=
1.55
0.04).
Combined
electronic
nose
gas
chromatography-ion
mobility
spectrometry
(GC-IMS)
found
HAD
facilitated
conversion
precursors
into
Ethyl
formate,
rose
oxide,
(Z)-3-hexenol
(M).
SDMLE
contained
higher
levels
pentanal,
(E)-2-hexenal
(D),
(E)-2-pentanone,
3-Methyl-2-butenal
ethyl
butyrate,
1-penten-3-one
(D).
diversity
novel
volatile
compounds
(VOCs),
18
newly
identified
species.
In
conclusion,
FD
is
a
potential
method
effectively
reduce
degradation
MLE
during
process.
Biology,
Journal Year:
2022,
Volume and Issue:
11(2), P. 233 - 233
Published: Feb. 1, 2022
The
concept
of
ecosystem
services
is
widely
understood
as
the
and
benefits
thatecosystems
provide
to
humans,
they
have
been
categorised
into
provisioning,
regulating,
supporting,
cultural
services.
This
article
aims
an
updated
overview
that
honey
bee
Apis
mellifera
provides
humans
well
ecosystems.
We
revised
role
bees
pollinators
in
natural
ecosystems
preserve
restore
local
biodiversity
wild
plants;
agro-ecosystems,
this
species
used
enhance
crop
yield
quality,
meeting
increasing
food
demand.
Beekeeping
activity
not
only
with
high-quality
but
also
substances
raw
materials
pharmaceuticals,
polluted
areas,
convey
valuable
information
on
environmental
presence
pollutants
their
impact
human
health.
Finally,
symbolic
tradition,
mysticism,
values
habitats
are
presented.
Overall,
we
suggest
value
most
important
played
by
insect
species,
it
may
help
revitalise
strengthen
intimate
reciprocal
relationship
between
world,
avoiding
inaccuracy
considering
mere
providers
humans.
Molecules,
Journal Year:
2023,
Volume and Issue:
28(3), P. 1510 - 1510
Published: Feb. 3, 2023
Royal
jelly
(RJ)
has
been
one
of
the
most
widely
used
natural
products
in
alternative
medicine
for
centuries.
Being
produced
by
both
hypopharyngeal
and
mandibular
glands,
RJ
exhibits
an
extraordinary
complexity
terms
its
composition,
including
proteins,
lipids,
carbohydrates,
polyphenols,
vitamins,
hormones.
Due
to
heterogeneous
structure,
displays
various
functional
roles
honeybees,
being
involved
nutrition,
learning,
memory,
social
behavior.
Furthermore,
a
wide
range
studies
reported
therapeutic
properties,
anticancer,
anti-inflammatory,
antioxidant
activities,
name
few.
In
this
direction,
there
is
health-related
problems
which
medical
area
specialists
researchers
are
continuously
trying
find
cure,
such
as
cancer,
atherosclerosis,
or
infertility.
For
mentioned
diseases
more,
it
proven
that
key
player
finding
valuable
treatment.
review,
great
impact
agent
highlighted,
with
focus
on
activities.
Moreover,
we
link
apitherapeutic
potential
discussing
composition.
Herein,
discuss
novel
present
latest
research
work.
Molecules,
Journal Year:
2022,
Volume and Issue:
27(14), P. 4594 - 4594
Published: July 19, 2022
Propolis
has
gained
wide
popularity
over
the
last
decades
in
several
parts
of
world.
In
parallel,
literature
about
propolis
composition
and
biological
properties
increased
markedly.
A
great
number
papers
have
demonstrated
that
from
different
world
is
composed
mainly
phenolic
substances,
frequently
flavonoids,
derived
plant
resins.
a
relevant
role
increasing
social
immunity
bee
hives.
Experimental
evidence
indicates
its
components
activity
against
bacteria,
fungi,
viruses.
Mechanisms
action
on
viruses
are
known
for
components.
Experiments
shown
may
act
synergistically
with
antibiotics,
antifungals,
antivirus
drugs,
permitting
administration
lower
doses
drugs
higher
antimicrobial
effects.
The
current
trend
growing
resistance
microbial
pathogens
to
available
encouraged
introduction
therapy
infectious
diseases.
Because
widely
variable,
standardized
extracts
been
produced.
Successful
clinical
trials
included
as
medicine
dentistry
an
adjuvant
treatment
patients
COVID-19.
Present
health
conditions
encourage
initiatives
toward
spread
niche
propolis,
not
only
traditional
alternative
but
also
protagonist
anti-infectious
therapy.
Production
other
apiary
products
environmentally
friendly
contribute
alleviating
crisis
decline
populations.
production
had
social-economic
relevance
Brazil,
providing
benefits
underprivileged
people.
Pharmaceuticals,
Journal Year:
2024,
Volume and Issue:
17(5), P. 646 - 646
Published: May 16, 2024
Beekeeping
provides
products
with
nutraceutical
and
pharmaceutical
characteristics.
These
are
characterized
by
abundance
of
bioactive
compounds.
For
different
reasons,
honey,
royal
jelly,
propolis,
venom,
pollen
beneficial
to
humans
animals
could
be
used
as
therapeutics.
The
pharmacological
action
these
is
related
many
their
constituents.
main
components
honey
include
oligosaccharides,
methylglyoxal,
jelly
proteins
(MRJPs),
phenolics
Royal
contains
jelleins,
royalisin
peptides,
MRJPs,
derivatives
hydroxy-decenoic
acid,
particularly
10-hydroxy-2-decenoic
acid
(10-HDA),
which
possess
antibacterial,
anti-inflammatory,
immunomodulatory,
neuromodulatory,
metabolic
syndrome-preventing,
anti-aging
properties.
Propolis
has
a
plethora
activities
that
referable
compounds
such
caffeic
phenethyl
ester.
Peptides
found
in
bee
venom
phospholipase
A2,
apamin,
melittin.
In
addition
being
vitamin-rich,
also
includes
unsaturated
fatty
acids,
sterols,
express
antiatherosclerotic,
antidiabetic,
anti-inflammatory
Therefore,
the
constituents
hive
particular
different.
All
have
been
investigated
for
properties
numerous
research
studies.
This
review
aims
provide
thorough
screening
chemicals
honeybee
biological
effects.
manuscript
may
impetus
branch
unconventional
medicine
goes
name
apitherapy.
Pharmaceutics,
Journal Year:
2022,
Volume and Issue:
14(4), P. 750 - 750
Published: March 30, 2022
Skin
tissue
regeneration
is
one
of
the
population’s
most
common
problems,
and
complications
that
may
appear
in
healing
process
can
have
detrimental
consequences.
An
alternative
to
conventional
treatments
could
be
represented
by
sustainable
materials
based
on
natural
products,
such
as
honey
its
derivates
(propolis,
royal
jelly,
bee
pollen,
beeswax,
venom).
They
exhibit
significant
inhibitory
activities
against
bacteria
great
potential
dermal
regeneration.
Research
pharmaceutical
field
demonstrates
medication
combined
with
products
deliver
better
results.
The
advantages
include
minimizing
side
effects
maintaining
same
effectiveness
using
low
concentrations
antibiotic,
anti-inflammatory,
or
chemotherapy
drugs.
Several
studies
suggested
replace
antimicrobial
activity
efficiency
antibiotics,
but
further
investigation
needed
establish
a
topical
mixture’s
potential,
including
honey,
propolis.
Bee
seem
complete
each
other’s
deficiencies,
their
mixture
impact
wound
process.
topic
addressed
this
paper
highlights
usefulness
propolis,
venom
re-epithelization
bacterial
infections.
Pharmaceutics,
Journal Year:
2022,
Volume and Issue:
14(6), P. 1142 - 1142
Published: May 27, 2022
Royal
jelly
(RJ)
is
one
of
the
most
valued
natural
products
and
known
for
its
health-promoting
properties.
Due
to
therapeutic
effects,
it
has
been
used
in
medicine
since
antiquity.
Nowadays,
several
studies
indicate
that
RJ
acts
as
a
powerful
antimicrobial
agent.
Indeed,
researchers
shed
light
on
antioxidant
anticancer
activity.
RJ’s
biological
properties
are
related
bioactive
compounds,
such
proteins,
peptides,
phenolic,
fatty
acids.
The
aim
this
review
highlight
recent
findings
main
compounds
correlated
with
available
literature
suggests
these
can
be
an
alternative
approach
order
enhance
human
health.
Moreover,
throughout
paper,
we
underline
prominent
antibacterial
effect
against
target
bacterial
strains.
In
addition,
briefly
discuss
other
activities,
antioxidative
outstanding
product.
Life,
Journal Year:
2023,
Volume and Issue:
13(7), P. 1573 - 1573
Published: July 17, 2023
Royal
jelly
(RJ),
a
highly
nutritious
natural
product,
has
gained
recognition
for
its
remarkable
health-promoting
properties,
leading
to
widespread
use
in
the
pharmaceutical,
food,
and
cosmetic
industries.
Extensive
investigations
have
revealed
that
RJ
possesses
broad
spectrum
of
therapeutic
effects,
including
anti-inflammatory,
antioxidant,
antitumor,
anti-aging,
antibacterial
activities.
Distinctive
among
bee
products,
exhibits
significantly
higher
water
relatively
lower
sugar
content.
It
is
characterized
by
substantial
protein
content,
making
it
valuable
source
this
essential
macronutrient.
Moreover,
contains
diverse
array
bioactive
substances,
such
as
lipids,
phenolic
compounds,
flavonoids,
organic
acids,
minerals,
vitamins,
enzymes,
hormones.
This
review
aims
provide
an
overview
current
research
on
components
present
their
associated
qualities.
According
existing
literature,
these
substances
hold
great
potential
alternative
approaches
enhancing
human
health.
Notably,
emphasizes
anti-inflammatory
properties
RJ,
particularly
relation
inflammatory
diseases,
multiple
sclerosis
(MS),
rheumatoid
arthritis
(RA),
bowel
diseases
(IBD).
Furthermore,
we
delve
into
antitumor
antioxidant
activities
aiming
deepen
our
understanding
biological
functions.
By
shedding
light
multifaceted
benefits
seeks
encourage
utilization
inspire
further
investigation
field.
Nutrients,
Journal Year:
2024,
Volume and Issue:
16(3), P. 393 - 393
Published: Jan. 29, 2024
Metabolic
disorders,
encompassing
diabetes
mellitus,
cardiovascular
diseases,
gastrointestinal
etc.,
pose
a
substantial
global
health
threat,
with
rising
morbidity
and
mortality
rates.
Addressing
these
disorders
is
crucial,
as
conventional
drugs
often
come
high
costs
adverse
effects.
This
review
explores
the
potential
of
royal
jelly
(RJ),
natural
bee
product
rich
in
bioactive
components,
an
alternative
strategy
for
managing
metabolic
diseases.
RJ
exhibits
diverse
therapeutic
properties,
including
antimicrobial,
estrogen-like,
anti-inflammatory,
hypotensive,
anticancer,
antioxidant
review’s
focus
on
investigating
how
its
components
impact
conditions
like
disease,
illnesses.
Evidence
suggests
that
serves
complementary
treatment
various
issues,
notably
demonstrating
cholesterol-
glucose-lowering
effects
diabetic
rats.
Specific
RJ-derived
metabolites,
such
10-hydroxy-2-decenoic
acid
(10-HDA),
also
known
“Queen
acid,”
show
promise
reducing
insulin
resistance
hyperglycemia.
Recent
research
highlights
RJ’s
role
modulating
immune
responses,
enhancing
anti-inflammatory
cytokines,
suppressing
key
inflammatory
mediators.
Despite
promising
findings,
further
needed
to
comprehensively
understand
mechanisms
underlying