Unveiling the role of functional foods with emphasis on prebiotics and probiotics in human health: A review

Journal of Functional Foods, Journal Year: 2024, Volume and Issue: 119, P. 106337 - 106337

Published: July 6, 2024

Functional foods particularly prebiotics and probiotics have attracted a lot of attention due to their ability alter gut microbiota an impact on number health disease-related factors, in relation human recent years. are that provide benefits beyond simple sustenance. They contain biologically active ingredients offer additional when consumed regular basis as part balanced diet. Prebiotics, which indigestible fibers specifically promote the growth activity beneficial bacteria, probiotics, live microorganisms upon consumption sufficient amount, shown great promise modifying composition function microbiota. The identified review problem involves clarifying precise impacts immune system function, composition, metabolic health, disease prevention. This emphasizes numerous advantages preserving balance microbiota, boosting immunity, enhancing parameters, reducing risk diseases. also insight advances formulation functional mitigating conditions synergy between prebiotics.

Language: Английский

---

Understanding the Interplay between Dietary Fiber, Polyphenols, and Digestive Enzymes

Food Hydrocolloids, Journal Year: 2025, Volume and Issue: unknown, P. 111310 - 111310

Published: Feb. 1, 2025

Language: Английский

---

Grain bound polyphenols: Molecular interactions, release characteristics, and regulation mechanisms of postprandial hyperglycemia

Food Research International, Journal Year: 2025, Volume and Issue: 208, P. 116291 - 116291

Published: March 16, 2025

Language: Английский

---

Conjugation of coconut protein with ferulic acid promotes interfacial adsorption and mitigates lipid oxidation in O/W emulsion

Food Hydrocolloids, Journal Year: 2024, Volume and Issue: 156, P. 110371 - 110371

Published: June 29, 2024

Language: Английский

---

Structural characterization and antioxidant activity mechanism of the ferulic acid-rich subfraction from sugar beet pectin

Carbohydrate Polymers, Journal Year: 2024, Volume and Issue: 347, P. 122691 - 122691

Published: Aug. 30, 2024

Language: Английский

---

The effects of inulin on solubilizing and improving anti-obesity activity of high polymerization persimmon tannin

International Journal of Biological Macromolecules, Journal Year: 2024, Volume and Issue: 270, P. 132232 - 132232

Published: May 9, 2024

Language: Английский

---

The gut-liver axis in fatty liver disease: role played by natural products

Frontiers in Pharmacology, Journal Year: 2024, Volume and Issue: 15

Published: April 15, 2024

Fatty liver disease, a condition characterized by fatty degeneration of the liver, mainly classified as non-alcoholic disease (NAFLD) and alcoholic (ALD), has become leading cause cirrhosis, cancer death. The gut-liver axis is bidirectional relationship between gut its microbiota liver. can communicate with through bile ducts, while portal vein transports products flora to intestinal metabolites directly indirectly regulate hepatic gene expression, an imbalance in thus contributing development disease. Utilizing natural for prevention treatment various metabolic diseases prevalent practice, it anticipated represent forthcoming trend drugs combating NAFLD/ALD. This paper discusses mechanism enterohepatic summarizes important role plant regulating axis, provides theoretical basis subsequent new clinical research.

Language: Английский

---

The regulation of glucose and lipid metabolism through the interaction of dietary polyphenols and polysaccharides via the gut microbiota pathway

Food & Function, Journal Year: 2024, Volume and Issue: 15(16), P. 8200 - 8216

Published: Jan. 1, 2024

Interactions of polyphenols and polysaccharides regulate glycolipid metabolism through the gut microbiota, which is achieved regulation metabolites, intestinal barrier function, signaling pathways.

Language: Английский

---

The Role of Diet, Additives, and Antibiotics in Metabolic Endotoxemia and Chronic Diseases

Metabolites, Journal Year: 2024, Volume and Issue: 14(12), P. 704 - 704

Published: Dec. 13, 2024

Background/Objectives: Dietary patterns, including high-fat and high-carbohydrate diets (HFDs HCDs), as well non-dietary factors such food additives antibiotics, are strongly linked to metabolic endotoxemia, a critical driver of low-grade chronic inflammation. This review explores the mechanisms through which these impair intestinal permeability, disrupt gut microbial balance, facilitate lipopolysaccharide (LPS) translocation into bloodstream, contributing disorders obesity, type 2 diabetes mellitus, inflammatory bowel disease. Methods: The analysis integrates findings from recent studies on effects dietary components microbiota interactions barrier function systemic Focus is given experimental designs assessing permeability using biochemical histological methods, alongside profiling in both human animal models. Results: HFDs HCDs were shown increase LPS levels, inducing dysbiosis compromising integrity. resulting endotoxemia promoted state inflammation, disrupting regulation pathogenesis various diseases. Food antibiotics further exacerbated by altering composition increasing permeability. Conclusions: Diet-induced alterations dysfunction emerge key mediators related disorders. Addressing patterns their impact health crucial for developing targeted interventions. Further research warranted standardize methodologies elucidate translating clinical applications.

Language: Английский

---

Feruloylacetone and Its Analog Demethoxyferuloylacetone Mitigate Obesity-Related Muscle Atrophy and Insulin Resistance in Mice

Journal of Agricultural and Food Chemistry, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 4, 2025

Obesity-induced muscle alterations, such as inflammation, metabolic dysregulation, and myosteatosis, lead to a decline in mass function, often resulting sarcopenic obesity. Currently, there are no definitive treatments for obesity beyond lifestyle changes dietary supplementation. Feruloylacetone (FER), thermal degradation product of curcumin, its analog demethoxyferuloylacetone (DFER), derived from the bisdemethoxycurcumin, have shown potential antiobesity effects previous studies. This study investigates impact FER DFER on obesity-related glucose intolerance atrophy. High-fat diet (HFD) feeding resulted reduction increased intramuscular triglyceride accumulation, both which were mitigated by The supplements activated PI3K/Akt/mTOR signaling pathway, enhanced protein synthesis, decreased markers degradation. Additionally, supplementation improved homeostasis HFD-fed mice. also promoted formation gut microbial consortium comprising Blautia intestinalis, Dubosiella newyorkensis, Faecalicatena fissicatena, Waltera Clostridium viride, Caproiciproducens galactitolivorans, contributed obesity-induced chronic inflammation. These findings suggest, first time, that may prevent complications, including atrophy insulin resistance, thereby warranting further research into their long-term efficacy safety.

Language: Английский

---