Journal of Hazardous Materials, Journal Year: 2024, Volume and Issue: unknown, P. 135789 - 135789
Published: Sept. 1, 2024
Language: Английский
Journal of Hazardous Materials, Journal Year: 2024, Volume and Issue: unknown, P. 135789 - 135789
Published: Sept. 1, 2024
Language: Английский
Journal of Hazardous Materials, Journal Year: 2023, Volume and Issue: 463, P. 132865 - 132865
Published: Oct. 27, 2023
Language: Английский
Citations
27The Science of The Total Environment, Journal Year: 2023, Volume and Issue: 892, P. 164541 - 164541
Published: May 31, 2023
Language: Английский
Citations
23Journal of Hazardous Materials, Journal Year: 2024, Volume and Issue: 466, P. 133585 - 133585
Published: Jan. 22, 2024
Language: Английский
Citations
15The Science of The Total Environment, Journal Year: 2023, Volume and Issue: 889, P. 164242 - 164242
Published: May 17, 2023
Language: Английский
Citations
20Environmental Research, Journal Year: 2023, Volume and Issue: 243, P. 117870 - 117870
Published: Dec. 9, 2023
Language: Английский
Citations
17Environmental Pollution, Journal Year: 2024, Volume and Issue: 349, P. 123968 - 123968
Published: April 15, 2024
Language: Английский
Citations
7Chemosphere, Journal Year: 2023, Volume and Issue: 327, P. 138489 - 138489
Published: March 28, 2023
Language: Английский
Citations
14Environmental Science & Technology, Journal Year: 2023, Volume and Issue: 57(50), P. 21348 - 21357
Published: Dec. 5, 2023
As the first isopropanol chiral triazole fungicide, mefentrifluconazole has broad prospects for application. In this study, stereoselective stability, bioactivity, fate, and biotoxicity were systematically investigated. Our results indicated that stability of enantiomers differed between environmental media, they stable in water sediment dark. The bactericidal activity R-mefentrifluconazole against four target pathogens was 4.6–43 times higher than S-mefentrifluconazole. water-sediment system, S-mefentrifluconazole dissipated faster water; however, its accumulation capacity zebrafish. S-Mefentrifluconazole induced more differentially expressed genes (DEGs) proteins (DEPs) zebrafish did R-mefentrifluconazole. Multiomics sequencing showed enhanced antioxidant, detoxification, immune, metabolic functions by interacting with related proteins. Based on AlphaFold2 modeling molecular docking, had different binding modes key zebrafish, which may be main reason differences bioactivity biotoxicity. excellent low biotoxicity, R-enantiomer can developed to improve reduce risk mefentrifluconazole.
Language: Английский
Citations
14Journal of Hazardous Materials, Journal Year: 2024, Volume and Issue: 469, P. 134020 - 134020
Published: March 13, 2024
Language: Английский
Citations
5The Science of The Total Environment, Journal Year: 2024, Volume and Issue: 944, P. 174014 - 174014
Published: June 15, 2024
Language: Английский
Citations
5