Recent advances in biomaterials for tissue-engineered constructs: Essential factors and engineering techniques DOI Creative Commons

Shiva Norouzi,

Nikoo Saveh Shemshaki,

Ehsan Norouzi

et al.

Materials Today Chemistry, Journal Year: 2024, Volume and Issue: 37, P. 102016 - 102016

Published: April 1, 2024

Tissue-engineered constructs can replicate the structural and physiological properties of natural tissues. The be designed to address transplantation issues affected by shortage donor tissues organs. One major concerns in tissue engineering is design development structures that improve interaction between materials cells provide an ideal platform for form functional tissue. Several contributing factors need considered fabricate constructs, including biomaterials, biological, topographical, biophysical, morphological either alone or combination. Here, we review application, advancement, future directions these essential designing developing regeneration. In particular, focus on original approaches tools construct parameters engineering.

Language: Английский

Biopolymeric sustainable materials and their emerging applications DOI
Zia Ullah Arif, Muhammad Yasir Khalid, Muhammad Fahad Sheikh

et al.

Journal of environmental chemical engineering, Journal Year: 2022, Volume and Issue: 10(4), P. 108159 - 108159

Published: June 28, 2022

Language: Английский

Citations

200

Smart and Multifunctional Materials Based on Electroactive Poly(vinylidene fluoride): Recent Advances and Opportunities in Sensors, Actuators, Energy, Environmental, and Biomedical Applications DOI Creative Commons
Carlos M. Costa, Vanessa F. Cardoso, P. Martins

et al.

Chemical Reviews, Journal Year: 2023, Volume and Issue: 123(19), P. 11392 - 11487

Published: Sept. 20, 2023

From scientific and technological points of view, poly(vinylidene fluoride), PVDF, is one the most exciting polymers due to its overall physicochemical characteristics. This polymer can crystalize into five crystalline phases be processed in form films, fibers, membranes, specific microstructures, being physical properties controllable over a wide range through appropriate chemical modifications. Moreover, PVDF-based materials are characterized by excellent chemical, mechanical, thermal, radiation resistance, for their outstanding electroactive properties, including high dielectric, piezoelectric, pyroelectric, ferroelectric response, best among systems thus noteworthy an increasing number technologies. review summarizes critically discusses latest advances PVDF copolymers, composites, blends, main characteristics processability, together with tailorability implementation areas sensors, actuators, energy harvesting storage devices, environmental microfluidic, tissue engineering, antimicrobial applications. The conclusions, challenges future trends concerning application also presented.

Language: Английский

Citations

149

Additive manufacturing of smart polymeric composites: Literature review and future perspectives DOI Creative Commons
Hamid Ikram, Ans Al Rashid, Muammer Koç‬

et al.

Polymer Composites, Journal Year: 2022, Volume and Issue: 43(9), P. 6355 - 6380

Published: Aug. 12, 2022

Abstract The latest developments in smart systems for improved human lives with advanced biomedical devices have evolved out of multi‐disciplinary scientific studies, including medicine, biology, material sciences, design, manufacturing, artificial intelligence, microelectronics, and so forth. growth such intelligent is primarily possible innovative materials, which demonstrate the response to various external stimuli like temperature, heat, moisture, light, electromagnetic field, chemical alteration. Such materials been recently fabricated using different additive manufacturing techniques devise personalized unique, complex, novel structures that can adjust conditions over time are specifically attributed 4D printing. Novel further improve continued be explored employed. This review paper investigates functional polymer nanocomposites, offer compliant flexible processes high strength, low cost, long‐term stability. study aims deliver a comprehensive deep understanding fundamental mechanisms involved, future possibilities this area research.

Language: Английский

Citations

91

3D/4D printed bio-piezoelectric smart scaffolds for next-generation bone tissue engineering DOI Creative Commons
Annan Chen, Jin Su,

Yinjin Li

et al.

International Journal of Extreme Manufacturing, Journal Year: 2023, Volume and Issue: 5(3), P. 032007 - 032007

Published: May 24, 2023

Abstract Piezoelectricity in native bones has been well recognized as the key factor bone regeneration. Thus, bio-piezoelectric materials have gained substantial attention repairing damaged by mimicking tissue’s electrical microenvironment (EM). However, traditional manufacturing strategies still encounter limitations creating personalized scaffolds, hindering their clinical applications. Three-dimensional (3D)/four-dimensional (4D) printing technology based on principle of layer-by-layer forming and stacking discrete demonstrated outstanding advantages fabricating scaffolds a more complex-shaped structure. Notably, 4D functionality-shifting can provide time-dependent programmable tissue EM response to external stimuli for In this review, we first summarize physicochemical properties commonly used (including polymers, ceramics, composites) representative biological findings Then, discuss latest research advances 3D terms feedstock selection, process, induction strategies, potential Besides, some related challenges such scalability, resolution, stress-to-polarization conversion efficiency, non-invasive ability after implantation put forward. Finally, highlight shape/property/functionality-shifting smart engineering (BTE). Taken together, review emphasizes appealing utility 3D/4D printed piezoelectric next-generation BTE implants.

Language: Английский

Citations

91

Piezoelectric Effect Polyvinylidene Fluoride (PVDF): From Energy Harvester to Smart Skin and Electronic Textiles DOI
Zhangbin Feng, Ziquan Zhao, Yanan Liu

et al.

Advanced Materials Technologies, Journal Year: 2023, Volume and Issue: 8(14)

Published: May 5, 2023

Abstract With the great demand for flexible self‐powered sensors and nanogenerators, polyvinylidene fluoride (PVDF) is widely investigated outstanding piezoelectric dielectric constant. In pursuit increasing β content, electrospinning exhibited to be an effective method without external high voltage pooling or mechanical stretching thus considered a cost‐effective simple method, because molecular dipoles in PVDF can aligned during process of with field stretching. The methods improving characteristics are briefly introduced this review, fibers including uniaxial fibers, highly core–shell Janus revealed, research on theoretical modeling carried out efficiency design nanogenerator. Last, studies prospective applications based electrospun its copolymer PVDF‐TrFE, from smart skin, energy harvesters electronic textiles, being conducted.

Language: Английский

Citations

73

Piezoelectric Biomaterials Inspired by Nature for Applications in Biomedicine and Nanotechnology DOI
Siying Chen, Xiaoyu Tong,

Yehong Huo

et al.

Advanced Materials, Journal Year: 2024, Volume and Issue: 36(35)

Published: June 22, 2024

Bioelectricity provides electrostimulation to regulate cell/tissue behaviors and functions. In the human body, bioelectricity can be generated in electromechanically responsive tissues organs, as well biomolecular building blocks that exhibit piezoelectricity, with a phenomenon known piezoelectric effect. Inspired by natural bio-piezoelectric phenomenon, efforts have been devoted exploiting high-performance synthetic biomaterials, including molecular materials, polymeric ceramic composite materials. Notably, biomaterials polarize under mechanical strain generate electrical potentials, which used fabricate electronic devices. Herein, review article is proposed summarize design research progress of devices toward bionanotechnology. First, functions regulating electrophysiological activity from cellular tissue level are introduced. Next, recent advances structure-property relationship various provided detail. following part, applications engineering, drug delivery, biosensing, energy harvesting, catalysis systematically classified discussed. Finally, challenges future prospects presented. It believed this will provide inspiration for development innovative fields biomedicine nanotechnology.

Language: Английский

Citations

40

Recent progress in electrospun polyvinylidene fluoride (PVDF)-based nanofibers for sustainable energy and environmental applications DOI Creative Commons
Fatemeh Mokhtari, Akbar Samadi, Ahmed O. Rashed

et al.

Progress in Materials Science, Journal Year: 2024, Volume and Issue: unknown, P. 101376 - 101376

Published: Sept. 1, 2024

Language: Английский

Citations

21

The potential of organic piezoelectric materials for next-generation implantable biomedical devices DOI Creative Commons
Arshad Khan, Ravindra Joshi, Manish Kumar Sharma

et al.

Nano Trends, Journal Year: 2024, Volume and Issue: 6, P. 100032 - 100032

Published: March 21, 2024

Piezoelectricity or piezoelectric effect is a phenomenon by which mechanical energy converted into electrical and vice versa. Piezoelectric has been observed in several organic materials. Therefore, past few years materials have received significant research interests biomedical applications specifically for fabrication of implantable devices because their high performance, excellent biocompatibility biodegradability, superior properties, cheap process. This article provides comprehensive review the recent progress on It extensively covers properties preparation methods different including amino acids, peptides, proteins, polysaccharides, polymers (such as PVDF, PLLA, PHB), well representative device namely biosensing, tissue regeneration, drug delivery. Finally, discusses challenges future directions this field.

Language: Английский

Citations

18

Review on Polyvinylidene Fluoride-Based Triboelectric Nanogenerators for Applications in Health Monitoring and Energy Harvesting DOI

Amrutha Bindhu,

Arun Anand Prabu, Madhvesh Pathak

et al.

ACS Applied Electronic Materials, Journal Year: 2024, Volume and Issue: 6(1), P. 47 - 72

Published: Jan. 3, 2024

To meet future demands for sustainable and environmentally friendly technology, many research groups are focusing on triboelectric nanogenerators (TENGs), which can scavenge convert the available mechanical energy into electrical energy. Researchers working to comprehend influence of material surfaces as well properties that play an important role in determining overall output performance TENGs. The selection tribonegative tribopositive materials based charge triboseries different processes manufacturing triboactive its surface modification roles attaining optimal TENG performance. most significant is polyvinylidene fluoride (PVDF), electroactive polar β-crystalline phase responsible higher However, PVDF has some intrinsic limitations such lower conductivity dipole moment nonpolar α-crystalline at room temperature. Interestingly, these main factors determine applications harvesting wearable sensors. In this review, we have mainly focused varying processing methods like solution casting, 3-D printing, spin coating, electrospinning PVDF-based effect nanoscale crystalline also studied detail. Additionally, extensive analysis recent advancements health monitoring, sensors, TENGs included.

Language: Английский

Citations

17

The potential application of electrical stimulation in tendon repair: a review DOI Creative Commons
Xiao Yu,

Yihong Shen,

Jie Cui

et al.

Med-X, Journal Year: 2025, Volume and Issue: 3(1)

Published: March 4, 2025

Language: Английский

Citations

2