Selective enhancement of 1H signal from water and oil in porous media at low field with Overhauser DNP DOI Creative Commons
Devin M. Morin, Naser Ansaribaranghar,

Benjamin Nicot

et al.

Journal of Magnetic Resonance, Journal Year: 2024, Volume and Issue: 368, P. 107793 - 107793

Published: Oct. 31, 2024

In porous media MR studies, discriminating between oil and water presents a challenge because lifetimes are often similar spectra overlap. Low saturations might suggest an experimental strategy of increasing the static field for increased sensitivity, but susceptibility effects exacerbated at higher field. Overhauser dynamic nuclear polarization, effective low field, was employed with oil-soluble nitroxide to selectively enhance signals. We employ home-built 2 MHz ceramic magnet achieve selective enhancement oil, in bulk, rock core. For imaging, we 705 kHz 4 gauss/cm constant gradient configuration image hyperpolarized signal. A core flooding experiment undertaken highlight advantages enhancement. simple phase cycling technique may be cancel thermally polarized

Language: Английский

Zero- to ultralow-field nuclear magnetic resonance DOI Creative Commons
Danila A. Barskiy, John W. Blanchard, Dmitry Budker

et al.

Progress in Nuclear Magnetic Resonance Spectroscopy, Journal Year: 2025, Volume and Issue: unknown, P. 101558 - 101558

Published: Feb. 1, 2025

Language: Английский

Citations

2
Live magnetic observation of parahydrogen hyperpolarization dynamics DOI Creative Commons
James Eills, Morgan W. Mitchell,

Irene Marco Rius

et al.

Proceedings of the National Academy of Sciences, Journal Year: 2024, Volume and Issue: 121(43)

Published: Oct. 15, 2024

Hyperpolarized nuclear spins in molecules exhibit high magnetization that is unachievable by classical polarization techniques, making them widely used as sensors physics, chemistry, and medicine. The state of a hyperpolarized material, however, typically only studied indirectly with partial destruction magnetization, due to the nature conventional detection resonant-pickup NMR spectroscopy or imaging. Here, we establish atomic magnetometers sub-pT sensitivity an alternative modality detect real time complex dynamics materials without disturbing interrupting magnetogenesis process. As example are impossible means, examine parahydrogen-induced 1 H 13 C during adiabatic eigenbasis transformations at μ T-field avoided crossings. Continuous but nondestructive magnetometry reveals previously unseen spin dynamics, fidelity limits, backaction effects. second example, apply observe chemical-exchange-driven hyperpolarization [1– C]-pyruvate—the most important tracer for clinical metabolic approach can be readily combined other high-sensitivity applicable broader range general observation scenarios involving production, transport, systems interaction compounds.

Language: Английский

Citations

6
Open-source compact time-domain hydrogen (1H) NMR System for Field Deployment DOI Creative Commons

Winford Janvrin,

Jacob Martin,

Daniel Hancock

et al.

HardwareX, Journal Year: 2025, Volume and Issue: unknown, P. e00651 - e00651

Published: April 1, 2025

Language: Английский

Citations

0
Polarization losses from the nonadiabatic passage of hyperpolarized solutions through metallic components DOI Creative Commons
James Eills, Marc Azagra,

David Gómez-Cabeza

et al.

Journal of Magnetic Resonance Open, Journal Year: 2024, Volume and Issue: 18, P. 100144 - 100144

Published: Jan. 13, 2024

From complex-mixture analysis to in vivo molecular imaging, applications of liquid-state nuclear spin hyperpolarization have expanded widely over recent years. In most cases, hyperpolarized solutions are generated ex situ and transported from the polarization instrument measurement device. The sample usually survives this transport, since changes magnetic fields that external typically adiabatic (slow) with respect internal dynamics. passage polarized samples through weakly components such as stainless steel syringe needles ferrules is not always adiabatic, which can lead near-complete destruction magnetization. To avoid effect becoming "folklore" field NMR, we present a systematic investigation highlight problem investigate possible solutions. Experiments were carried out on: (i) dissolution-DNP-polarized [1-13C]pyruvate NMR detection at 1.4 T, (ii) 1.5-T-polarized H2O 2.5 μT. We show degree adiabaticity passing metal parts intrinsically unpredictable, likely depending on many factors solution flow rate, remanent ferromagnetism metal, species. However, magnetization effects be suppressed by application an order 0.1–10 mT.

Language: Английский

Citations

1
DETECTION OF METRONIDAZOLE AND FAMPRIDINE BY NMR AT ZERO AND ULTRALOW MAGNETIC FIELD DOI
Dudari B. Burueva, James Eills, Román Picazo‐Frutos

et al.

Журнал Экспериментальной и Теоретической Физики, Journal Year: 2024, Volume and Issue: 166(4), P. 566 - 570

Published: Nov. 1, 2024

Language: Английский

Citations

1
Automated test apparatus for bench-testing the magnetic field homogeneity of NMR transceiver coils DOI Creative Commons
Jose L. Uribe,

Matthew D. Jimenez,

Jessica I. Kelz

et al.

Journal of Magnetic Resonance Open, Journal Year: 2023, Volume and Issue: 18, P. 100142 - 100142

Published: Dec. 21, 2023

We describe an automated hands-off bench testing method for measuring the magnetic field profile of transceiver coils nuclear resonance (NMR). The scattering parameter (S-parameter) data is measured using a portable network analyzer, and results are automatically exported to computer plotting viewing. This assay dramatically reduces time needed measure (B1) homogeneity coil while also improving accuracy relative manual operation. Here, we demonstrate on saddle solution-state NMR probe in comparison profiles obtained spectroscopy measurements. axial radial variable-pitch solenoid.

Language: Английский

Citations

2
Optically detected nuclear magnetic resonance above and far below earth's magnetic field: spin dynamics and relaxation in unconventional regimes DOI Creative Commons
Sven Bodenstedt

Published: Feb. 15, 2024

(English) This thesis describes theoretical background, simulations, experimental apparatus and measurements of nuclear spin dynamics via optically pumped magnetometers in unconventional magnetic field regimes. It is divided into four parts: Magnetometry, Nuclear Magnetic Resonance Spectroscopy, Relaxation Dispersion, Spin Control, each looking at different aspects this topic. The magnetometry section how through integration techniques from DC spin-exchange relaxation-free rf magnetometers, a widely tunable magnetometer developed that offers nearly flat response up to few kHz with sensitivity less than 20 fT √Hz. Within range, it surpasses the capabilities inductive detection methods eliminates necessity for cryogenic temperatures are required superconducting quantum interference devices (SQUIDs). subsequent part employs conducting resonance spectroscopy experiments involving coupled systems. A comprehensive analysis undertaken ascertain optimal yields most precise determination J-coupling constant. shown some systems ultra-low regime advantages compared zero- high-field regime. key factor choosing relaxation’s strong dependency, explored thesis’s third part. thoroughly examines subject discussing long-lived coherences impact long correlations molecular dynamics. experimentally investigates by adapting established fast-field cycling method fields combining optical detection. thesis’ s final focuses on enhancing manipulation advanced ensure selective, efficient, accurate, fault-tolerant control. Ultra-low possess unique attributes, making even basic like spin-selective resonant pulses challenging implement. To address this, novel concepts were devised, enabling effective control rivaling or surpassing counterparts. efficiency these improved pulse sequences demonstrated dynamical decoupling, polarimetry, spectral filtering experiments. (Català) Aquesta tesi doctoral descriu la teoria, simulacions, aparell i mesuraments de dinàmiques espín per mitjà magnetòmetres bombeig òptic en règims magnètics no convencionals. està dividida quatre magnetometria, espectroscòpia ressonància magnètica nuclear, dispersió relaxació nuclear. La secció magnetometria com, mitjançant integració les tècniques d’intercanvi lliure RF, s’ha desenvolupat un magnetòmetre àmpliament ajustable que ofereix una resposta gairebé plana des fins uns pocs amb sensibilitat menys En aquest rang, sobrepassa capacitats mètodes detecció inductiva elimina necessitat criogèniques necessàries aparells superconductors d'interferència quàntica o SQUIDs (per sigles anglès). següent s'empra el realitzar d'espectroscòpia sistemes espines nuclears acoblats. Es fa anàlisi exhaustiva trobar camp magnètic dóna determinació més precisa constant J d'acoblament. demostra alguns règim camps ultra baixos ofereixen avantatges quan es comparen els zero y alt règim. Un clau triar és forta dependència l'espín camp. s'explora tercera d'aquesta al rang convencional baixos, discussió sobre coherències persistents llarga vida l'impacte correlacions esteses moleculars. Aquest estudi realitza experimentalment adaptant mètode establert rotació ràpida (fast cycling) combinant-ho òptica. s'enfoca millorar manipulació d'espín avançats asseguren selectiu, eficient, exacte prova d'errors. Els tenen atributs únics fan tot bàsiques com polsos ressonants selectius siguin difícils d'implementar. Per resoldre això, s'han nous conceptes permeten efectiu similars millors contraparts alts. L'eficàcia d'aquestes seqüències millorades desacoblament dinàmic, polarimetria filtratge espectral.

Citations

0
Selective enhancement of 1H signal from water and oil in porous media at low field with Overhauser DNP DOI Creative Commons
Devin M. Morin, Naser Ansaribaranghar,

Benjamin Nicot

et al.

Journal of Magnetic Resonance, Journal Year: 2024, Volume and Issue: 368, P. 107793 - 107793

Published: Oct. 31, 2024

In porous media MR studies, discriminating between oil and water presents a challenge because lifetimes are often similar spectra overlap. Low saturations might suggest an experimental strategy of increasing the static field for increased sensitivity, but susceptibility effects exacerbated at higher field. Overhauser dynamic nuclear polarization, effective low field, was employed with oil-soluble nitroxide to selectively enhance signals. We employ home-built 2 MHz ceramic magnet achieve selective enhancement oil, in bulk, rock core. For imaging, we 705 kHz 4 gauss/cm constant gradient configuration image hyperpolarized signal. A core flooding experiment undertaken highlight advantages enhancement. simple phase cycling technique may be cancel thermally polarized

Language: Английский

Citations

0