Polyphenols and their applications: An approach in food chemistry and innovation potential

Food Chemistry, Journal Year: 2020, Volume and Issue: 338, P. 127535 - 127535

Published: July 9, 2020

Polyphenols are compounds naturally present in fruits and vegetables that gaining more attention due to their therapeutic effects potential technological applications. In this review, we intend demonstrate the importance of some phenolic compounds, addressing biological for applications various industrial fields. The intake these appropriate concentrations can promising prevention diseases such as diabetes, obesity, Parkinson's, Alzheimer's, others. They also be used improve physicochemical properties starch, preservation foods, natural dyes, prebiotic ingredients, hydrogels nanocomplexes. addition, have innovation most diverse fields, including organic fine chemistry, basic materials pharmaceuticals, food chemical engineering, etc.

Language: Английский

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Health benefits of polyphenols: A concise review

Journal of Food Biochemistry, Journal Year: 2022, Volume and Issue: 46(10)

Published: June 13, 2022

Plants produce polyphenols, which are considered highly essential functional foods in our diet. They classified into several groups according to their diverse chemical structures. Flavanoids, lignans, stilbenes, and phenolic acids the four main families of polyphenols. Several vivo vitro research have been conducted so far evaluate health consequences. Polyphenols serve a vital function protection organism from external stimuli eliminating reactive oxygen species (ROS), instigators illnesses. present tea, chocolate, fruits, vegetables with potential positively influence human health. For instance, cocoa flavan-3-ols associated decreased risk myocardial infarction, stroke, diabetes. diet also help improve lipid profiles, blood pressure, insulin resistance, systemic inflammation. Quercetin, flavonoid, resveratrol, stilbene, linked improved cardiovascular Dietary polyphenols elicit therapeutic effects might be attributed, at least part, bidirectional association gut microbiome. This is because known affect microbiome composition ways that lead better Specifically, converts bioactive compounds effects. In this review, antioxidant, cytotoxicity, anti-inflammatory, antihypertensive, anti-diabetic actions described based on findings experimental trials. Practical applications The non-communicable diseases (NCDs) burden has increasing worldwide due sedentary lifestyle other factors such as smoking, junk food, etc. Scientific literature evidence supports use plant-based food agents could alleviate NCD's burden. Thus, consuming polyphenolic natural sources an effective solution mitigate NCDs concerns. It discussed how antioxidants medicinal plants prevent or repair damage caused by free radicals, oxidative stress.

Language: Английский

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The Two-Way Polyphenols-Microbiota Interactions and Their Effects on Obesity and Related Metabolic Diseases

Frontiers in Nutrition, Journal Year: 2019, Volume and Issue: 6

Published: Dec. 20, 2019

Metabolic diseases can change the gut microbiota composition and function, pathogenic bacteria contribute to development of metabolic disorders. Polyphenols may act in favor increase beneficial hamper bacteria. In addition, on polyphenols their bioavailability. This two-way interaction between could affect human metabolism reduce cardiometabolic risk. Despite possible benefits for health through modulating microbiome, studies are scarce present several limitations. review provides an overview polyphenol–microbiota its effects

Language: Английский

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Effects of Synbiotic Supplement on Human Gut Microbiota, Body Composition and Weight Loss in Obesity

Nutrients, Journal Year: 2020, Volume and Issue: 12(1), P. 222 - 222

Published: Jan. 15, 2020

Targeting gut microbiota with synbiotics (probiotic supplements containing prebiotic components) is emerging as a promising intervention in the comprehensive nutritional approach to reducing obesity. Weight loss resulting from low-carbohydrate high-protein diets can be significant but has also been linked potentially negative health effects due increased bacterial fermentation of undigested protein within colon and subsequent changes composition. Correcting obesity-induced disruption more effective than supplementation probiotics alone because components support growth survival positive bacteria therein. The purpose this placebo-controlled clinical trial was evaluate synbiotic supplement on composition, richness diversity associations microbial species body composition parameters biomarkers obesity human subjects participating weight program. probiotic component used study contained Lactobacillus acidophilus, Bifidobacterium lactis, longum, bifidum galactooligosaccharide mixture. results showed no statistically differences (body mass, BMI, fat percentage, lean bone mineral content) between placebo groups at end (3-month intervention, 20 based low-carbohydrate, high-protein, reduced energy diet). Synbiotic abundance associated effects, especially Lactobacillus, it appeared increase richness. A decreasing trend observed trial, which may imply effect diet Regression analysis performed correlate following found an association decrease over time blood glucose abundance, particularly group. However, waist circumstance, mass abundance. obtained conclusion that modulates by increasing beneficial species.

Language: Английский

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Curcumin, Quercetin, Catechins and Metabolic Diseases: The Role of Gut Microbiota

Nutrients, Journal Year: 2021, Volume and Issue: 13(1), P. 206 - 206

Published: Jan. 12, 2021

Polyphenols (PPs) are the naturally occurring bioactive components in fruits and vegetables, they most abundant antioxidant human diet. Studies suggesting that ingestion of PPs might be helpful to ameliorate metabolic syndromes may contribute prevention several chronic disorders like diabetes, obesity, hypertension, colon cancer. have structural diversity which impacts their bioavailability as accumulate large intestine extensively metabolized through gut microbiota (GM). Intestinal transforms into metabolites make them bioactive. Interestingly, not only GM act on metabolize but also modulate composition GM. Thus, change from pathogenic beneficial ones health associated diseases. However, overcome low PPs, various approaches been developed improve solubility transportation gut. In this review, we present evidence supporting changes occur after reactions (curcumin, quercetin, catechins) effect leads improving overall helping disorders.

Language: Английский

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Polyphenols—Gut Microbiota Interrelationship: A Transition to a New Generation of Prebiotics

Nutrients, Journal Year: 2021, Volume and Issue: 14(1), P. 137 - 137

Published: Dec. 28, 2021

The present review summarizes the studies carried out on this topic in last five years. According to new definitions, among all compounds included group of prebiotics, polyphenols are probably most important secondary metabolites produced by plant kingdom. Many these types have low bioavailability, therefore reaching colon unaltered form. Once colon, interact with intestinal microbes bidirectionally modulating them and, consequently, releasing metabolites. Despite much research various metabolites, little is known about chemistry metabolic routes used different bacteria species. In context, aims investigate prebiotic effect preclinical and clinical studies, highlighting that consumption leads an increase beneficial bacteria, as well production valuable conclusion, there evidence supporting polyphenols, but further needed humans.

Language: Английский

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Dietary polyphenols to combat the metabolic diseases via altering gut microbiota

Trends in Food Science & Technology, Journal Year: 2019, Volume and Issue: 93, P. 81 - 93

Published: Sept. 10, 2019

Language: Английский

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Interaction of dietary polyphenols and gut microbiota: Microbial metabolism of polyphenols, influence on the gut microbiota, and implications on host health

Food Frontiers, Journal Year: 2020, Volume and Issue: 1(2), P. 109 - 133

Published: June 1, 2020

Abstract The human gastrointestinal tract is inhabited by a vast number of microorganisms that are called as the microbiota. Each individual harbors unique gut microbial composition, this composition evolves throughout host's lifetime and it easily affected internal or external changes. It has been shown microbiota plays crucial role in health complex community ability to interact with each other immune system, presence absence some major species can affect homeostasis. Diet be considered one pivotal factors modulating functionality, integrity, first organ exposed components diet. In review, we have focused on effects polyphenols, key compounds healthy diet several biological activities, their biotransformation microbiota, effect reciprocal interactions disease.

Language: Английский

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Desulfovibrio vulgaris, a potent acetic acid-producing bacterium, attenuates nonalcoholic fatty liver disease in mice

Gut Microbes, Journal Year: 2021, Volume and Issue: 13(1)

Published: Jan. 1, 2021

The emerging evidence supports the use of prebiotics like herb-derived polysaccharides for treating nonalcoholic fatty liver disease (NAFLD) by modulating gut microbiome. present study was initiated on microbiota-dependent anti-NAFLD effect Astragalus (APS) extracted from mongholicus Bunge in high-fat diet (HFD)-fed mice. However, exact mechanisms underlying beneficial effects APS NAFLD formation remain poorly understood.Co-housing experiment used to assess microbiota dependent APS. Then, targeted metabolomics and metagenomics were adopted determining short-chain acids (SCFAs) bacteria that specifically enriched Further vitro carried out test capacity SCFAs-producing identified bacterium. Finally, efficacy bacterium tested HFD-fed mice.Our results first demonstrated mice contribution microbiota. Moreover, our indicated SCFAs, predominantly acetic acid elevated APS-supplemented ex vivo experiment. Metagenomics revealed D. vulgaris Desulfovibrio genus not only APS, but also a potent generator acid, which showed significant In addition, modulated hepatic gene expression pattern lipids metabolism, particularly suppressed synthase (FASN) CD36 protein expression.Our demonstrate is effective attenuating steatosis possibly through producing modulation metabolism studies are warranted explore long-term impacts host mechanism.

Language: Английский

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Immune boosting functional foods and their mechanisms: A critical evaluation of probiotics and prebiotics

Biomedicine & Pharmacotherapy, Journal Year: 2020, Volume and Issue: 130, P. 110625 - 110625

Published: Aug. 10, 2020

Comprehensive studies conducted on the link between gut microbiome and immunity in recent decades have correspondingly led to ever increasing interests functional foods, especially probiotics prebiotics. Probiotics prebiotics play crucial roles managing intestinal microbiota order improve host health, even though their influence other body sites are being investigated. Different colonic bacteria metabolize dietary produce beneficial metabolites, short chain fatty acids (SCFAs) that luminal contents performance, while positively affecting overall physiology. Thus, this review provides a general perspective of immune system, system its microbiota. The also evaluates foods with critical but comprehensive perspectives into prebiotics, boosting mechanisms action. It is recommended further mechanistic translational promote social life empower poverty-stricken communities.

Language: Английский

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