Royal Society of Chemistry eBooks,
Journal Year:
2024,
Volume and Issue:
unknown, P. 95 - 120
Published: Dec. 20, 2024
Fluorometric
sensors
and
devices
are
important
tools
for
the
detection
measurement
of
biomarkers,
which
indicators
biological
processes
diseases.
These
involve
emission
light
from
fluorescent
molecules
upon
interaction
with
target
biomolecules,
resulting
in
a
measurable
signal.
Fluorescence-based
techniques,
instance,
fluorescence
microscopy,
fluorometry,
resonance
energy
transfer
(FRET),
probes,
enable
researchers
to
study
high
sensitivity
specificity.
offer
numerous
benefits
over
conventional
methods,
like
higher
sensitivity,
selectivity,
versatility,
ability
sense
various
biomarkers
instantaneously.
In
this
chapter,
we
provide
an
overview
recent
developments
fluorometric
biomarker
detection,
including
design
principles,
sensing
mechanisms,
fabrication
techniques
developing
sensors.
The
challenges
future
directions
technology
also
discussed.
This
chapter
highlights
importance
these
advancing
our
understanding
systems
their
potential
improving
healthcare,
food
safety,
environmental
monitoring.
Chemical Engineering Journal Advances,
Journal Year:
2024,
Volume and Issue:
17, P. 100583 - 100583
Published: Jan. 6, 2024
Carbon
dots
(CDs)
are
nanostructures
containing
mainly
carbon
atoms
and
abundant
functional
groups.
With
remarkable
adjustable
physicochemical
properties,
CDs
have
excellent
hydrophilicity,
photoluminescence
(PL),
biocompatibility,
low
toxicity.
Although
the
numerous
advantages
make
a
research
target
for
synthesizing
advanced
materials,
some
limitations
pertinent
must
be
corrected.
Rare
earth
elements
(RE)
candidates
doping
CDs,
obtaining
hybrid
materials
called
RE-CDs
to
optimize
luminescence
applicability,
quantum
yields.
Hybrids
allow
combination
of
advantageous
characteristics
both
RE,
drastically
improving
their
luminous
magneto-optical
imaging
performance
opening
door
practical
technological
applications.
To
date,
no
studies
in
literature
provided
in-depth
analyses
methods
used
prepare
RE-CDs,
characterization
techniques
used,
challenges,
critical
analysis
what
could
improved
synthesis
by
proposing
solutions.
fill
this
gap,
review
initially
presents
detailed
survey
RE
separately.
Subsequently,
addressed,
as
well
obtainment,
commonly
characterizations,
recent
applications,
from
analyte
detection
functionality
medical
nanodevices.
Finally,
criticisms
suggestions
future
work
also
discussed
inspire
new
discoveries
about
potential
derived
RE-CDs.
RSC Advances,
Journal Year:
2024,
Volume and Issue:
14(4), P. 2380 - 2390
Published: Jan. 1, 2024
Cisplatin
(CIS)
and
etoposide
(ETP)
combination
therapy
is
highly
effective
for
treating
various
cancers.
However,
the
potential
pharmacokinetic
interactions
between
these
drugs
necessitates
selective
sensing
methods
to
quantitate
both
CIS
ETP
levels
in
patient's
plasma.
This
work
develops
a
dual
fluorescence
probe
strategy
using
glutathione-capped
copper
nanoclusters
(GSH-CuNCs)
nitrogen-doped
carbon
dots
(N-CDs)
simultaneous
analysis
of
ETP.
The
signal
GSH-CuNCs
at
615
nm
increased
linearly
with
concentration
while
N-CD
emission
480
remained
unaffected.
Conversely,
was
selectively
enhanced
by
no
interference
CuNC
fluorescence.
Extensive
materials
characterization
including
UV-vis,
spectroscopy,
XRD,
TEM
confirmed
synthesis
nanoprobes.
sensor
showed
high
sensitivity
limits
detection
6.95
ng
mL
