Association between COVID-19 vaccination and menstruation: a state of the science review
BMJ Sexual & Reproductive Health,
Journal Year:
2024,
Volume and Issue:
50(3), P. 212 - 225
Published: June 10, 2024
Menstrual
health
is
a
key
patient-reported
outcome
beyond
its
importance
as
general
indicator
of
and
fertility.
However,
menstrual
function
was
not
measured
in
the
clinical
trials
COVID-19
vaccines.
The
purpose
this
review
to
synthesise
existing
literature
on
relationship
between
vaccination
outcomes.
Language: Английский
Menstrual disorders following COVID-19 vaccination: a review using a systematic search
Veerle R. Smaardijk,
No information about this author
Rana Jajou,
No information about this author
A. Kant
No information about this author
et al.
Frontiers in Drug Safety and Regulation,
Journal Year:
2024,
Volume and Issue:
4
Published: Jan. 31, 2024
Introduction:
Menstrual
disorders
are
commonly
reported
after
COVID-19
vaccination
and
heavy
menstrual
bleeding
was
added
to
the
product
information
of
vaccines
Moderna
Pfizer.
The
aim
this
review,
using
a
systematic
search,
is
provide
an
overview
available
literature
on
risk
vaccination.
Methods:
review
conducted
according
Preferred
Reporting
Items
for
Systematic
reviews
Meta-Analysis
(PRISMA)
guidelines.
A
PubMed
search
performed
15
August
2023,
including
solely
quantitative
studies
in
English
Dutch.
Results:
total
61
were
included,
which
40
cross-sectional
studies,
18
cohort
three
self-controlled
case
series.
Outcomes
included
wide
variety
disorders,
changes
cycle
length
(
n
=
54),
amount
44),
menses
30),
experience
(pre)menstrual
pain
21),
breakthrough
18).
All
found
higher
percentage
at
least
one
disorder
first
different
types
doses.
Discussion:
In
conclusion,
evidence
suggests
that
may
cause
women
reproductive
age.
However,
there
need
more
longitudinal
because
important
limitations
study
designs
many
studies.
Although
short-lived
predominantly
mild,
it
healthcare
professionals
be
informed
about
these
potential
adverse
reactions
assess
events
clinical
trials
vaccines.
Language: Английский
Adverse Menstrual Events Reported After and Before (or Without) COVID‐19 Vaccination: A Systematic Review and Meta‐Analysis of Comparative Observational Studies
Frank Peinemann,
No information about this author
Doris Oberle,
No information about this author
Ursula Drechsel‐Bäuerle
No information about this author
et al.
Pharmacoepidemiology and Drug Safety,
Journal Year:
2024,
Volume and Issue:
33(8)
Published: Aug. 1, 2024
ABSTRACT
Background
Reports
of
adverse
menstrual
events
emerged
during
the
COVID‐19
vaccination
campaign
in
multiple
countries.
This
raised
question
whether
these
reports
were
caused
by
vaccines.
The
aim
this
systematic
review
was
to
evaluate
comparative
studies
on
topic
(registered
at
PROSPERO
[CRD42022324973]).
Methods
We
included
observational
such
as
cohort
and
surveys
comparing
response
self‐reported
questionnaires
between
post‐
versus
pre‐vaccination
data.
PubMed
Cochrane
Library
searches
conducted
1
September
2023.
primary
outcome
incidence
any
prespecified
event,
measure
risk
ratio.
meta‐analysis
using
Mantel–Haenszel
method
random
effects
model.
summarized
results
factors
well
key
findings
included.
Results
retrieved
161
references
from
electronic
databases
additional
sources
lists.
Of
those,
we
considered
21
studies.
event
reported
12
resulted
a
pooled
estimate
(risk
ratio
1.13;
95%
CI,
0.96–1.31)
that
did
not
favor
group.
analysis
constrained
considerable
clinical
statistical
heterogeneity.
Risk
for
changes
history
infection,
concern
about
vaccines,
smoking,
previous
cycle
irregularities,
depression,
stress,
other
issues.
Conclusions
group
heterogeneity
prevalent
among
Most
suggested
temporary,
minor,
nonserious.
Language: Английский
Covid-19 vaccination and menstrual bleeding disturbances among women of fertile age: a Norwegian registry study
European Journal of Epidemiology,
Journal Year:
2024,
Volume and Issue:
39(10), P. 1127 - 1138
Published: Oct. 1, 2024
Abstract
This
study
evaluated
the
relationship
between
Covid-19
vaccination
and
menstrual
bleeding
disturbances
using
a
large
national
registry
linkage
including
666,467
women
20
40
years
of
age
residing
in
Norway
on
January
1st,
2019.
Information
vaccination—BNT162b2
mRNA-1273
—
was
obtained
from
Norwegian
registry.
Diagnoses
(absent/scanty,
excessive,
irregular/frequent
menstruation,
intermenstrual
bleeding)
general
practitioner
database.
We
examined
new-onset
Cox
regression
comparing
vaccinated
to
unvaccinated
women,
where
contributed
follow-up
time
as
until
day
vaccination.
In
addition,
we
conducted
self-controlled
case-series
analysis,
sensitivity
analysis
excluding
all
those
who
remained
throughout
pandemic,
evaluate
role
unmeasured
confounding.
observed
an
increased
risk
several
after
against
Covid-19,
ranging
adjusted
HR
(aHR)
1.18
(95%
CI:
1.04,
1.33)
for
1.29
1.23,
1.36)
periods.
However,
estimates
were
fully
attenuated
when
at
end
(aHRs
0.97
1.08).
No
differences
identified
according
vaccine
dose
or
type.
Our
case
series
confirmed
no
first
vaccination,
though
there
slightly
61
days
with
2.
conclusion,
modestly
appeared
reflect
confounding
by
never
received
vaccinations,
associations
did
not
remain
compared
before
among
ever
women.
Language: Английский
The Impact of the COVID-19 Pandemic on Menstrual Cycle in Saudi Females in Jeddah City
Nedaa Bahkali,
No information about this author
Reham Ahmad Alsharif,
No information about this author
Dana Sawan
No information about this author
et al.
International Journal of Women s Health and Reproduction Sciences,
Journal Year:
2023,
Volume and Issue:
12(4), P. 160 - 166
Published: Dec. 8, 2023
Objectives:
This
study
aimed
to
determine
the
impact
of
COVID-19
on
menstrual
cycle
Saudi
females
in
Jeddah
City.
Materials
and
Methods:
In
this
cross-sectional
study,
we
conducted
a
total
421
online
surveys
phone
call
interviews
with
participants
between
19
45
years
age,
living
City,
Arabia,
who
were
not
pregnant,
had
no
gynecological
problems
or
abnormalities.
Interviews
January
April
2022,
data
analyzed
using
SPSS
version
23.
Results:
Most
responders
single
normal
body
mass
index
(BMI).
During
pandemic,
majority
(75.8%)
did
have
heavy,
unpleasant
periods
(54.6%),
missed
(54.6%,
78.1%,
respectively).
The
reported
changes
observed
terms
premenstrual
symptoms
(PMS)
(61.5%),
libido/sex
drive
remained
unchanged
for
most
(88.1%).
Of
those
heavy
(n=125),
18.4%
(n=23)
changes.
239
experience
pain
before
COVID-19,
nine
(3.8%)
experiencing
it
during
pandemic.
Conclusions:
There
significant
period
women
bleeding,
painful
periods,
small
differences
psychological
challenges
Language: Английский