Impact of the COVID-19 Pandemic on the Diagnosis of Tuberculosis in Brazil: Is the WHO End TB Strategy at Risk?

Frontiers in Pharmacology, Journal Year: 2022, Volume and Issue: 13

Published: June 29, 2022

Background: In 2014, the World Health Organization (WHO) launched "post-2015 End TB strategy", that aims to end global tuberculosis (TB) epidemic by 2030. However, COVID-19 pandemic has severely impacted public health and strict measures control coronavirus spread can affect management of other diseases, such as TB. Herein, we aimed assess impact on diagnosis in Brazil, during 2020. Methods: We carried out an ecological population-based study, using spatial analysis techniques. The variables used were new cases TB, pulmonary (PTB), also baciloscopy-positive (BP) Brazil between 2015 percentage changes (% change) was calculated verify if there increase or decrease 2020, along with time trend analyses given Joinpoint regression model. Also, interrupted series before after onset Brazil. Spatial distribution maps elaborated, considering % change each Brazilian state. Findings: Data showed a reduction (-8.3%) PTB (-8.1%) irruption pandemic. Likewise, 22 states depicted diagnosis. An expressive BP (-17.1%) observed. Interestingly, decline diagnoses from March revealed all had progressive PB cases, on, highest percentages December (-100% -75%). Interpretation: Taken together, our demonstrated its regions, signaling serious WHO "End Strategy" plan.

Language: Английский

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Impact of the COVID-19 Pandemic Surveillance of Visceral Leishmaniasis in Brazil: An Ecological Study

Infectious Disease Reports, Journal Year: 2024, Volume and Issue: 16(1), P. 116 - 127

Published: Feb. 9, 2024

The aim of the study was to assess impact COVID-19 pandemic on notification new VL cases in Brazil 2020. It is an ecological and time-series (2015–2020) with spatial analysis techniques, whose units were 5570 Brazilian municipalities. population consisted all recorded between 2015 P-score calculated estimate percentage variation cases. Global local univariate Moran’s Indices retrospective space–time scan statistics used analyses, respectively. expected that there would be 3627 2020, but 1932 reported (−46.73%). All regions presented a negative registration cases, Southeast (−54.70%), North (−49.97%), Northeast (−44.22%) standing out. There dependence disease nationwide both periods, before during first year pandemic. significant reduction incidence These findings reinforce need for better preparedness health system, especially situations epidemics.

Language: Английский

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Impact of the COVID-19 pandemic on the actions of the Schistosomiasis Control Program in an endemic area in Northeastern Brazil

Acta Tropica, Journal Year: 2023, Volume and Issue: 240, P. 106859 - 106859

Published: Feb. 11, 2023

Language: Английский

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Impact of COVID-19 on the neglected tropical diseases: a scoping review

Infectious Diseases of Poverty, Journal Year: 2024, Volume and Issue: 13(1)

Published: July 29, 2024

Abstract Background This study investigates the impact of COVID-19 pandemic on prevalence, management, and control neglected tropical diseases (NTDs) highlighting current or prospective research development funding for, execution of, NTD programmes. review was conducted to determine if, how, NTDs were affected by COVID-19, whether those effects will delay elimination goals Sustainable Development goals. Methods Using open-source available data from policy documentation official websites relevant stakeholders including but not limited World Health Organization (WHO) documents policies, government foreign aid documents, Policy Cures G-Finder reports, this scoping explored ongoing challenges supporting (R&D) for in maintaining programs; examined constraints posed management disruptions healthcare services, reduction finance potential long-term implications consequences poorer, populations low middle income-countries (LMICs). done a literature search, publications subject an initial practical screening step ensure most selected full screening, with focus designated topic NTDs. We further undertook evaluation socio-economic factors exacerbating burden. Results Multiple setbacks, likely affect programmes progress towards their targets identified study. R&D AIDs TB has declined since high point 2019, malaria 2018. Significant changes allocation within are observed post pandemic, because prioritization among donors. Diseases which least investment reported place, prior (mycetoma, taeniasis/cysticercosis, trachoma Buruli ulcer) have been particularly impacted pandemic. specific schistosomiasis, leprosy, rabies that caused programs. Pandemic restrictions disrupted essential medical supply manufacturing distribution impacting immunization programs hindered efforts spread infectious diseases. experienced numerous setbacks delays mass drug administration (e.g. schistosomiasis), cancelled delayed vaccination rabies) closure testing facilities resulted reduced diagnosis, treatment, disease all Lockdowns clinic closures causing disruption services restricted surveillance treatment Community fears around contracting exacerbated service delivery. Disparities global vaccine widened LMICs facing access vaccines Finally, led increased poverty poor marginalized communities, nutrition, education long term control. Conclusions The profoundly health equity. Attention diverted sectors, significantly affecting set out Organization’s Roadmaps. Ongoing funding, economic crises, logistics chain as well deepening put strain already weak systems LMIC challenges. In particular, long-reaching need cooperation renewed roadmap back track. Targets milestones unlikely be met without significant recovery, place. Graphical

Language: Английский

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Effects of Covid-19 Pandemic in the Surveillance and Control of Neglected Tropical Diseases and Malaria: A Systematic Review

Current Tropical Medicine Reports, Journal Year: 2025, Volume and Issue: 12(1)

Published: Feb. 5, 2025

Language: Английский

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NOVAS PROPOSTAS DE ANÁLISE ESPACIAL E ESPAÇO-TEMPORAL DA DETECÇÃO GERAL DE HANSENÍASE E DOS CASOS NOVOS COM GRAU 2 DE INCAPACIDADE FÍSICA NA PARAÍBA: ESTUDO ECOLÓGICO, 2016 - 2020

Hygeia - Revista Brasileira de Geografia Médica e da Saúde, Journal Year: 2025, Volume and Issue: 21, P. e2109 - e2109

Published: Feb. 7, 2025

Objetivo: Propor a Razão de Taxas Espacial e Médias Espaço-Temporal aplicar sobre os casos novos hanseníase com Grau Incapacidade Física 2 na Paraíba. Métodos: Estudo ecológico tendo como lócus municípios do estado da Paraíba (2016 2020). Foram aplicadas estatística descritiva análise espacial por meio Espaço Temporal. Resultados: Evidenciou-se igual ou maior 1,0 em todo estado, maiores valores 6,2 (2016); 10,5 (2017); 11,3 (2018); 10,3 (2019); 7,6 (2020) relacionadas Taxa Detecção Geral, 29,8 24,3 22,0 33,2 41,8(2020) referentes Casos Incapacidade. Quanto Temporal variou 0 67,2 para Geral 15,5 Física, no período estudo, o que atesta heterogeneidade distribuição entre analisados. Conclusão: Constata-se utilização das análises propostas foi possível identificar contribuem formas diferenciadas frente à Paraíba, desta forma, deve-se se planejar ações mais fidedignas às necessidades cada município.

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Perfil clínico-epidemiológico dos casos de hanseníase dos estados da região Nordeste do Brasil no período de 2018-2022

Hansenologia Internationallis hanseníase e outras doenças infecciosas, Journal Year: 2025, Volume and Issue: 50, P. e40505 - e40505

Published: Feb. 25, 2025

Introdução: um dos desafios para o controle da hanseníase no Brasil é a falta de reconhecimento do panorama local doença na análise perfil sociodemográfico e clínico. Objetivo: analisar clínico-epidemiológico casos estados região Nordeste período 2018-2022. Métodos: este estudo ecológico foi realizado utilizando dados Sistema Informação Agravos Notificação População Residente disponibilizados pelo Departamento Informática Único Saúde. Foram selecionados notificados Brasil, seus estados, durante 2018 2022. Resultados: obteve maior número doença. Mais 50% ocorreram em homens, pessoas pardas faixa etária entre 20-59 anos. Foi observada queda considerável prevalência 2020 com aumento nos anos subsequentes. Os obtiveram características semelhantes. Maranhão apresentou absolutos prevalência. Conclusão: os resultados revelaram compatibilidade outras regiões endêmicas, destacando necessidade fortalecer vigilância epidemiológica promover ações educativas direcionadas às populações vulnerabilizadas, visando ampliar acesso ao diagnóstico precoce tratamento adequado.

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The Epidemiological Impact of Community-Based Skin Camps on Leprosy Control in East Hararghe Zone, Ethiopia: a Modelling Study

Journal of Epidemiology and Global Health, Journal Year: 2025, Volume and Issue: 15(1)

Published: March 4, 2025

Language: Английский

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Time trend and identification of risk areas for physical disability due to leprosy in Brazil: An ecological study, 2001-2022

BMC Infectious Diseases, Journal Year: 2025, Volume and Issue: 25(1)

Published: March 6, 2025

Leprosy is a chronic infectious disease that affects the peripheral nerves, leading to neurological damage and physical disability. This study analyzed temporal trend in rate of new leprosy cases with grade 2 disability Brazil identified spatial clusters risk for an ecological all (G2D) at diagnosis between 2001 2022 Brazil, macro-regions, states municipalities. Data were extracted from National System Notifiable Diseases Brazilian Institute Geography Statistics. Sociodemographic clinical variables such as age, sex, race/colour, education form analyzed, well time per million inhabitants. analysis was divided into three stages: 1- Descriptive socio-demographic profile; 2- Time series analysis: In this stage, joint-point regression model used; 3- Spatial analysis, using global local Moran statistics. There 50,466 G2D during period studied, 97.4% aged > 14 years, 70.2% male, 45.7% brown, 87.6% low education, 90.2% multibacillary 47.5% dimorphic form. downward detection 2, average annual reduction 2.8% (13.6/1 9.1/1 2022). The southeast, south north regions showed trend. A total 4 capitals decrease rate, most significant being Roraima (-11.0%/year). Tocantins only state upward (3.2%/year). 635 (14.1%) municipalities high-high quadrant. These belong 12 accounted 30% (n = 15,139) recorded country over 22 years analyzed. results suggest overall highlight geographical disparities occurrence Interventions promote early should be targeted areas highest

Language: Английский

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An interrupted time series study of the leprosy case detection in Brazil after the COVID-19 pandemic

Scientific Reports, Journal Year: 2025, Volume and Issue: 15(1)

Published: March 21, 2025

COVID-19 pandemics affected several health systems processes, including leprosy care. This study aimed to estimate the impact of pandemic on case detection rate in Brazil from 2017 2022. Data was retrieved Sinan, a Brazilian notification system, and monthly overall population individuals under 15 years age were main outcomes. The series interrupted February 2020, when public emergency declared Brazil. data analysed via Prais–Winsten regression. Over 72 months analysed, led an immediate 0.55 reduction (95% CI 0.48–0.62) rate, with subsequent increase 1.01 1.00–1.02). For age, caused 0.48 0.40–0.57), followed by 1.01–1.02) after onset pandemic. Subnational analysis revealed that most federative units trend for but high heterogeneity observed regarding age. Therefore, it is urgent target strategies minimize delayed diagnosis long-term consequences leprosy.

Language: Английский

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